AU646977B2 - Imidazolyl-propenoic acid derivatives - Google Patents

Imidazolyl-propenoic acid derivatives

Info

Publication number
AU646977B2
AU646977B2 AU26023/92A AU2602392A AU646977B2 AU 646977 B2 AU646977 B2 AU 646977B2 AU 26023/92 A AU26023/92 A AU 26023/92A AU 2602392 A AU2602392 A AU 2602392A AU 646977 B2 AU646977 B2 AU 646977B2
Authority
AU
Australia
Prior art keywords
imidazolyl
acid derivatives
propenoic acid
propenoic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU26023/92A
Other languages
English (en)
Other versions
AU2602392A (en
Inventor
Martin Dr. Beuck
Jurgen Dr. Dressel
Rudolf Dr. Hanko
Walter Dr. Hubsch
Stanislav Prof. Dr. Kazda
Andreas Dr. Knorr
Thomas Dr. Kramer
Ulrich Dr. Muller
Matthias dr. Muller-Gliemann
Johannes-Peter Dr. Stasch
Stefan Dr. Wohlfeil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2602392A publication Critical patent/AU2602392A/en
Application granted granted Critical
Publication of AU646977B2 publication Critical patent/AU646977B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU26023/92A 1991-10-01 1992-09-29 Imidazolyl-propenoic acid derivatives Ceased AU646977B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4132631A DE4132631A1 (de) 1991-10-01 1991-10-01 Imidazolyl-propensaeurederivate
DE4132631 1991-10-01

Publications (2)

Publication Number Publication Date
AU2602392A AU2602392A (en) 1993-04-08
AU646977B2 true AU646977B2 (en) 1994-03-10

Family

ID=6441873

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26023/92A Ceased AU646977B2 (en) 1991-10-01 1992-09-29 Imidazolyl-propenoic acid derivatives

Country Status (15)

Country Link
US (1) US5294633A (cs)
EP (1) EP0535463A1 (cs)
JP (1) JPH05213938A (cs)
KR (1) KR930007936A (cs)
AU (1) AU646977B2 (cs)
CA (1) CA2079281A1 (cs)
CZ (1) CZ298892A3 (cs)
DE (1) DE4132631A1 (cs)
FI (1) FI924354L (cs)
HU (1) HUT62577A (cs)
IL (1) IL103291A0 (cs)
MX (1) MX9205436A (cs)
NO (1) NO923579L (cs)
TW (1) TW208701B (cs)
ZA (1) ZA927501B (cs)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
AT398202B (de) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
AU684916B2 (en) * 1994-03-16 1998-01-08 Sankyo Company Limited Ocular tension depressant
EP0754042A4 (en) * 1994-03-29 2004-06-23 Merck & Co Inc TREATING ATHEROSCLEROSIS WITH IMIDAZOLES BLOCKING THE ANGIOTENSIN II RECEPTOR
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
US20100120694A1 (en) 2008-06-04 2010-05-13 Synergy Pharmaceuticals, Inc. Agonists of Guanylate Cyclase Useful for the Treatment of Gastrointestinal Disorders, Inflammation, Cancer and Other Disorders
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (es) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2014151200A2 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
AU2014274812B2 (en) 2013-06-05 2018-09-27 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase C, method of making and using same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8043691A (en) * 1990-08-09 1992-02-13 Zeneca Limited Process for the manufacture of biphenylcarbonitriles
AU2602492A (en) * 1991-10-01 1993-04-08 Bayer Aktiengesellschaft Substituted imidazolyl-propenoic acid derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
DK0955294T3 (da) * 1989-06-14 2004-02-02 Smithkline Beecham Corp Imidazolylalkensyre
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
WO1991000277A1 (en) * 1989-06-30 1991-01-10 E.I. Du Pont De Nemours And Company Substituted imidazoles
HU215834B (hu) * 1989-06-30 1999-04-28 E. I. Du Pont De Nemours And Co. Eljárás aromás csoporttal szubsztituált imidazolszármazékok, valamint ezeket hatóanyagként tartalmazó gyógyszerkészítmények előállítására
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8043691A (en) * 1990-08-09 1992-02-13 Zeneca Limited Process for the manufacture of biphenylcarbonitriles
AU2602492A (en) * 1991-10-01 1993-04-08 Bayer Aktiengesellschaft Substituted imidazolyl-propenoic acid derivatives

Also Published As

Publication number Publication date
NO923579L (no) 1993-04-02
JPH05213938A (ja) 1993-08-24
US5294633A (en) 1994-03-15
KR930007936A (ko) 1993-05-20
AU2602392A (en) 1993-04-08
HU9203124D0 (en) 1992-12-28
FI924354A0 (fi) 1992-09-29
EP0535463A1 (de) 1993-04-07
CA2079281A1 (en) 1993-04-02
NO923579D0 (no) 1992-09-15
ZA927501B (en) 1993-05-03
MX9205436A (es) 1993-04-01
FI924354A7 (fi) 1993-04-02
HUT62577A (en) 1993-05-28
IL103291A0 (en) 1993-02-21
CZ298892A3 (en) 1993-04-14
FI924354L (fi) 1993-04-02
DE4132631A1 (de) 1993-04-08
TW208701B (cs) 1993-07-01

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