AU646977B2 - Imidazolyl-propenoic acid derivatives - Google Patents
Imidazolyl-propenoic acid derivativesInfo
- Publication number
- AU646977B2 AU646977B2 AU26023/92A AU2602392A AU646977B2 AU 646977 B2 AU646977 B2 AU 646977B2 AU 26023/92 A AU26023/92 A AU 26023/92A AU 2602392 A AU2602392 A AU 2602392A AU 646977 B2 AU646977 B2 AU 646977B2
- Authority
- AU
- Australia
- Prior art keywords
- imidazolyl
- acid derivatives
- propenoic acid
- propenoic
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- ZLSNPZVGNMESDB-UHFFFAOYSA-N 2-(1h-imidazol-2-yl)prop-2-enoic acid Chemical class OC(=O)C(=C)C1=NC=CN1 ZLSNPZVGNMESDB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4132631A DE4132631A1 (de) | 1991-10-01 | 1991-10-01 | Imidazolyl-propensaeurederivate |
DE4132631 | 1991-10-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2602392A AU2602392A (en) | 1993-04-08 |
AU646977B2 true AU646977B2 (en) | 1994-03-10 |
Family
ID=6441873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU26023/92A Ceased AU646977B2 (en) | 1991-10-01 | 1992-09-29 | Imidazolyl-propenoic acid derivatives |
Country Status (15)
Country | Link |
---|---|
US (1) | US5294633A (cs) |
EP (1) | EP0535463A1 (cs) |
JP (1) | JPH05213938A (cs) |
KR (1) | KR930007936A (cs) |
AU (1) | AU646977B2 (cs) |
CA (1) | CA2079281A1 (cs) |
CZ (1) | CZ298892A3 (cs) |
DE (1) | DE4132631A1 (cs) |
FI (1) | FI924354L (cs) |
HU (1) | HUT62577A (cs) |
IL (1) | IL103291A0 (cs) |
MX (1) | MX9205436A (cs) |
NO (1) | NO923579L (cs) |
TW (1) | TW208701B (cs) |
ZA (1) | ZA927501B (cs) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4132633A1 (de) * | 1991-10-01 | 1993-04-08 | Bayer Ag | Cyclisch substituierte imidazolyl-propensaeurederivate |
AT398202B (de) * | 1991-10-04 | 1994-10-25 | Chem Pharm Forsch Gmbh | Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung |
ATE266402T1 (de) * | 1994-03-16 | 2004-05-15 | Sankyo Co | Okulares hypotonikum |
CA2186606A1 (en) * | 1994-03-29 | 1995-10-05 | Edward B. Nelson | Treatment of atherosclerosis with angiotensin ii receptor blocking imidazoles |
CN103601792B (zh) | 2007-06-04 | 2016-06-29 | 协同医药品公司 | 有效用于胃肠功能紊乱、炎症、癌症和其他疾病治疗的鸟苷酸环化酶激动剂 |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
WO2009149279A2 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
US9486494B2 (en) | 2013-03-15 | 2016-11-08 | Synergy Pharmaceuticals, Inc. | Compositions useful for the treatment of gastrointestinal disorders |
WO2014151206A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
CA2913737A1 (en) | 2013-06-05 | 2014-12-11 | Synergy Pharmaceuticals, Inc. | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8043691A (en) * | 1990-08-09 | 1992-02-13 | Zeneca Limited | Process for the manufacture of biphenylcarbonitriles |
AU2602492A (en) * | 1991-10-01 | 1993-04-08 | Bayer Aktiengesellschaft | Substituted imidazolyl-propenoic acid derivatives |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5138069A (en) * | 1986-07-11 | 1992-08-11 | E. I. Du Pont De Nemours And Company | Angiotensin II receptor blocking imidazoles |
CA2018443A1 (en) * | 1989-06-14 | 1990-12-14 | Joseph A. Finkelstein | Imidazolyl-alkenoic acids |
DK0955294T3 (da) * | 1989-06-14 | 2004-02-02 | Smithkline Beecham Corp | Imidazolylalkensyre |
WO1991000281A2 (en) * | 1989-06-30 | 1991-01-10 | E.I. Du Pont De Nemours And Company | Fused-ring aryl substituted imidazoles |
DK0479903T3 (da) * | 1989-06-30 | 1996-03-18 | Du Pont | Substituerede imidazoler og deres anvendelse som angiotensin II hæmmere |
AU640417B2 (en) * | 1989-10-25 | 1993-08-26 | Smithkline Beecham Corporation | Substituted 5-((tetrazolyl)alkenyl)imidazoles |
-
1991
- 1991-10-01 DE DE4132631A patent/DE4132631A1/de not_active Withdrawn
-
1992
- 1992-09-14 TW TW081107193A patent/TW208701B/zh active
- 1992-09-15 NO NO92923579A patent/NO923579L/no unknown
- 1992-09-18 EP EP92115970A patent/EP0535463A1/de not_active Withdrawn
- 1992-09-21 US US07/947,869 patent/US5294633A/en not_active Expired - Fee Related
- 1992-09-24 MX MX9205436A patent/MX9205436A/es unknown
- 1992-09-25 JP JP4279236A patent/JPH05213938A/ja active Pending
- 1992-09-25 IL IL103291A patent/IL103291A0/xx unknown
- 1992-09-28 CA CA002079281A patent/CA2079281A1/en not_active Abandoned
- 1992-09-29 AU AU26023/92A patent/AU646977B2/en not_active Ceased
- 1992-09-29 FI FI924354A patent/FI924354L/fi not_active Application Discontinuation
- 1992-09-30 CZ CS922988A patent/CZ298892A3/cs unknown
- 1992-09-30 ZA ZA927501A patent/ZA927501B/xx unknown
- 1992-09-30 KR KR1019920017891A patent/KR930007936A/ko not_active Withdrawn
- 1992-10-01 HU HU9203124A patent/HUT62577A/hu unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU8043691A (en) * | 1990-08-09 | 1992-02-13 | Zeneca Limited | Process for the manufacture of biphenylcarbonitriles |
AU2602492A (en) * | 1991-10-01 | 1993-04-08 | Bayer Aktiengesellschaft | Substituted imidazolyl-propenoic acid derivatives |
Also Published As
Publication number | Publication date |
---|---|
CA2079281A1 (en) | 1993-04-02 |
EP0535463A1 (de) | 1993-04-07 |
FI924354A0 (fi) | 1992-09-29 |
AU2602392A (en) | 1993-04-08 |
ZA927501B (en) | 1993-05-03 |
HU9203124D0 (en) | 1992-12-28 |
IL103291A0 (en) | 1993-02-21 |
TW208701B (cs) | 1993-07-01 |
NO923579D0 (no) | 1992-09-15 |
KR930007936A (ko) | 1993-05-20 |
HUT62577A (en) | 1993-05-28 |
JPH05213938A (ja) | 1993-08-24 |
US5294633A (en) | 1994-03-15 |
MX9205436A (es) | 1993-04-01 |
FI924354A7 (fi) | 1993-04-02 |
NO923579L (no) | 1993-04-02 |
DE4132631A1 (de) | 1993-04-08 |
FI924354L (fi) | 1993-04-02 |
CZ298892A3 (en) | 1993-04-14 |
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