AU6418396A - Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide - Google Patents

Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide

Info

Publication number
AU6418396A
AU6418396A AU64183/96A AU6418396A AU6418396A AU 6418396 A AU6418396 A AU 6418396A AU 64183/96 A AU64183/96 A AU 64183/96A AU 6418396 A AU6418396 A AU 6418396A AU 6418396 A AU6418396 A AU 6418396A
Authority
AU
Australia
Prior art keywords
5alp
17beta
androst
phenylprop
epimers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64183/96A
Other languages
English (en)
Inventor
Enrico Di Salle
Marcella Nesi
Achille Panzeri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Pharmacia and Upjohn SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia and Upjohn SpA filed Critical Pharmacia and Upjohn SpA
Publication of AU6418396A publication Critical patent/AU6418396A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J73/00—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms
    • C07J73/001—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom
    • C07J73/005—Steroids in which the cyclopenta[a]hydrophenanthrene skeleton has been modified by substitution of one or two carbon atoms by hetero atoms by one hetero atom by nitrogen as hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU64183/96A 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide Abandoned AU6418396A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI95A1587 1995-07-21
IT95MI001587A IT1275594B1 (it) 1995-07-21 1995-07-21 Epimeri del (22rs)-n-(1,1,1-trifluoro-2-fenilprop-2-il)-3-osso -4-aza-5alfa-androst-1-ene-17beta-carbossammide
PCT/EP1996/002830 WO1997004002A1 (en) 1995-07-21 1996-06-28 EPIMERS OF (22RS)-N-(1,1,1-TRIFLUORO-2-PHENYLPROP-2-YL)-3-OXO-4-AZA-5α-ANDROST-1-ENE-17β-CARBOXAMIDE

Publications (1)

Publication Number Publication Date
AU6418396A true AU6418396A (en) 1997-02-18

Family

ID=11372032

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64183/96A Abandoned AU6418396A (en) 1995-07-21 1996-06-28 Epimers of (22RS)-N-(1,1,1-trifluoro-2-phenylprop-2-yl)-3-ox-4-aza-5alp ha-androst-1-ene-17beta-carboxamide

Country Status (17)

Country Link
EP (1) EP0782582A1 (no)
JP (1) JPH10506411A (no)
KR (1) KR970706298A (no)
CN (1) CN1159195A (no)
AR (1) AR003967A1 (no)
AU (1) AU6418396A (no)
BR (1) BR9606527A (no)
CA (1) CA2199273A1 (no)
EA (1) EA199700045A1 (no)
HU (1) HUP9702465A3 (no)
IL (1) IL120343A0 (no)
IT (1) IT1275594B1 (no)
MX (1) MX9701948A (no)
NO (1) NO971196L (no)
PL (1) PL319351A1 (no)
WO (1) WO1997004002A1 (no)
ZA (1) ZA965678B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000013509A1 (en) * 1998-09-09 2000-03-16 Merck & Co., Inc. Method of determining and reducing the risk of bph-related urologic events
EP1146873B1 (en) * 1999-01-25 2005-03-16 Smithkline Beecham Corporation Anti-androgens and methods for treating disease
CN100355772C (zh) * 2005-12-28 2007-12-19 天津大学 具有5α－还原酶抑制活性的甾体化合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9216284D0 (en) * 1992-07-31 1992-09-16 Erba Carlo Spa Fluorinated 17beta-substituted 4-aza-5alpha-androstane-3-one derivatives

Also Published As

Publication number Publication date
ITMI951587A1 (it) 1997-01-21
NO971196D0 (no) 1997-03-14
CA2199273A1 (en) 1997-02-06
ITMI951587A0 (it) 1995-07-21
IL120343A0 (en) 1997-06-10
BR9606527A (pt) 1997-12-23
PL319351A1 (en) 1997-08-04
ZA965678B (en) 1997-01-24
HUP9702465A2 (hu) 1998-05-28
JPH10506411A (ja) 1998-06-23
MX9701948A (es) 1997-06-28
CN1159195A (zh) 1997-09-10
HUP9702465A3 (en) 1998-11-30
IT1275594B1 (it) 1997-08-06
EA199700045A1 (ru) 1997-12-30
EP0782582A1 (en) 1997-07-09
AR003967A1 (es) 1998-09-30
WO1997004002A1 (en) 1997-02-06
NO971196L (no) 1997-03-14
KR970706298A (ko) 1997-11-03

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