AU622101B2 - Oral administration capsule with a nicotine-containing fluid medium - Google Patents
Oral administration capsule with a nicotine-containing fluid medium Download PDFInfo
- Publication number
- AU622101B2 AU622101B2 AU81712/87A AU8171287A AU622101B2 AU 622101 B2 AU622101 B2 AU 622101B2 AU 81712/87 A AU81712/87 A AU 81712/87A AU 8171287 A AU8171287 A AU 8171287A AU 622101 B2 AU622101 B2 AU 622101B2
- Authority
- AU
- Australia
- Prior art keywords
- nicotine
- capsule
- document
- fluid medium
- date
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 title claims abstract description 64
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 title claims abstract description 63
- 229960002715 nicotine Drugs 0.000 title claims abstract description 63
- 239000002775 capsule Substances 0.000 title claims abstract description 46
- 239000012530 fluid Substances 0.000 title claims abstract description 22
- 230000000391 smoking effect Effects 0.000 claims abstract description 11
- 239000000654 additive Substances 0.000 claims abstract description 7
- 210000002200 mouth mucosa Anatomy 0.000 claims description 11
- 235000019504 cigarettes Nutrition 0.000 claims description 10
- 238000000034 method Methods 0.000 claims description 10
- 238000010521 absorption reaction Methods 0.000 claims description 9
- 210000004369 blood Anatomy 0.000 claims description 8
- 239000008280 blood Substances 0.000 claims description 8
- 239000000779 smoke Substances 0.000 claims description 7
- 230000000694 effects Effects 0.000 claims description 4
- 235000019640 taste Nutrition 0.000 claims description 4
- 210000004556 brain Anatomy 0.000 claims description 3
- 210000001519 tissue Anatomy 0.000 claims description 3
- 230000002035 prolonged effect Effects 0.000 claims description 2
- 230000009747 swallowing Effects 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000003801 milling Methods 0.000 claims 1
- 206010012335 Dependence Diseases 0.000 abstract description 2
- 239000000796 flavoring agent Substances 0.000 abstract description 2
- 235000019634 flavors Nutrition 0.000 abstract description 2
- 235000003642 hunger Nutrition 0.000 abstract description 2
- 239000003814 drug Substances 0.000 description 5
- 229940079593 drug Drugs 0.000 description 3
- 108010009685 Cholinergic Receptors Proteins 0.000 description 2
- 102000034337 acetylcholine receptors Human genes 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 241001136792 Alle Species 0.000 description 1
- 208000024827 Alzheimer disease Diseases 0.000 description 1
- 208000019901 Anxiety disease Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 101100048372 Human cytomegalovirus (strain AD169) H301 gene Proteins 0.000 description 1
- 101100048373 Human cytomegalovirus (strain Merlin) UL18 gene Proteins 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 208000018737 Parkinson disease Diseases 0.000 description 1
- 101150037769 TRX2 gene Proteins 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 239000000443 aerosol Substances 0.000 description 1
- 235000019606 astringent taste Nutrition 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- OEYIOHPDSNJKLS-UHFFFAOYSA-N choline Chemical compound C[N+](C)(C)CCO OEYIOHPDSNJKLS-UHFFFAOYSA-N 0.000 description 1
- 229960001231 choline Drugs 0.000 description 1
- 230000001713 cholinergic effect Effects 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 210000003928 nasal cavity Anatomy 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 210000000653 nervous system Anatomy 0.000 description 1
- 239000002858 neurotransmitter agent Substances 0.000 description 1
- 210000001331 nose Anatomy 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 230000003204 osmotic effect Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 239000011505 plaster Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 208000009999 tuberous sclerosis Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/465—Nicotine; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/006—Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/34—Tobacco-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Addiction (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863639418 DE3639418A1 (de) | 1986-11-18 | 1986-11-18 | Nikotinhaltiges mittel |
| DE3639418 | 1986-11-18 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU8171287A AU8171287A (en) | 1988-06-16 |
| AU622101B2 true AU622101B2 (en) | 1992-04-02 |
Family
ID=6314221
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU81712/87A Ceased AU622101B2 (en) | 1986-11-18 | 1987-11-06 | Oral administration capsule with a nicotine-containing fluid medium |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0324794B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2602043B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN87107852A (cg-RX-API-DMAC7.html) |
| AT (1) | ATE72114T1 (cg-RX-API-DMAC7.html) |
| AU (1) | AU622101B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR8707879A (cg-RX-API-DMAC7.html) |
| DE (3) | DE3645036A1 (cg-RX-API-DMAC7.html) |
| DK (1) | DK173353B1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO1988003803A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5549906A (en) | 1993-07-26 | 1996-08-27 | Pharmacia Ab | Nicotine lozenge and therapeutic method for smoking cessation |
| US5362496A (en) * | 1993-08-04 | 1994-11-08 | Pharmetrix Corporation | Method and therapeutic system for smoking cessation |
| DE4440563A1 (de) * | 1994-11-12 | 1996-05-15 | Herzog Sen Rolf | Verfahren und Mittel zum Genuß von Tabak - Nikotin unter Vermeidung schädlicher Verbrennungs - Derivate |
| US5604231A (en) * | 1995-01-06 | 1997-02-18 | Smith; Carr J. | Pharmaceutical compositions for prevention and treatment of ulcerative colitis |
| US5846983A (en) * | 1996-02-09 | 1998-12-08 | Mayo Foundation For Medical Education And Research | Colonic delivery of nicotine to treat inflammatory bowel disease |
| AU2340397A (en) * | 1996-03-21 | 1997-10-10 | Mayo Foundation For Medical Education And Research | Use of nicotine to treat liver disease |
| GB9614902D0 (en) | 1996-07-16 | 1996-09-04 | Rhodes John | Sustained release composition |
| AUPO108596A0 (en) * | 1996-07-18 | 1996-08-08 | Collier, Gregory | Treatment of obesity |
| US6211194B1 (en) | 1998-04-30 | 2001-04-03 | Duke University | Solution containing nicotine |
| US6268386B1 (en) * | 1998-06-25 | 2001-07-31 | Marshall Anlauf Thompson | Nicotine beverage |
| GB2338896B (en) * | 1998-07-02 | 2003-05-21 | Reckitt & Colmann Prod Ltd | Chewable Capsules |
| DK1202736T3 (da) | 1999-07-28 | 2008-12-15 | Univ Leland Stanford Junior | Nikotin i terapeutisk angiogenese og vasculogenese |
| US8188043B2 (en) | 1999-07-28 | 2012-05-29 | The Board Of Trustees Of The Leland Stanford Jr. University | Nicotine in therapeutic angiogenesis and vasculogenesis |
| AT409219B (de) * | 1999-08-13 | 2002-06-25 | Red Bull Gmbh | Verwendung von nikotin zum herstellen von arzneimitteln |
| SE0104388D0 (sv) | 2001-12-27 | 2001-12-27 | Pharmacia Ab | New formulation and use and manufacture thereof |
| US20040002520A1 (en) * | 2002-07-01 | 2004-01-01 | Soderlund Patrick L. | Composition and method for cessation of Nicotine cravings |
| FI3473251T3 (fi) | 2002-12-20 | 2024-01-09 | Niconovum Ab | Nikotiini-selluloosa-kombinaatio |
| IL155666A (en) | 2003-04-29 | 2013-12-31 | Neurim Pharma 1991 | Insomnia treatment |
| US9119846B2 (en) | 2003-04-29 | 2015-09-01 | Neurim Pharmaceuticals (1991) Ltd. | Method and composition for enhancing cognition in alzheimer's patients |
| WO2005007068A1 (en) * | 2003-07-22 | 2005-01-27 | The Kiwigel Company Limited | Nicotine packaging system |
| NO20042835D0 (no) * | 2004-07-05 | 2004-07-05 | Nils-Erik Skeide | Innkapslet tobakksroyk |
| US8252321B2 (en) | 2004-09-13 | 2012-08-28 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like |
| US7780981B2 (en) | 2004-09-13 | 2010-08-24 | Chrono Therapeutics, Inc. | Biosynchronous transdermal drug delivery |
| AU2007224584A1 (en) | 2006-03-16 | 2007-09-20 | Niconovum Ab | Improved snuff composition |
| ES2521494T3 (es) * | 2007-04-02 | 2014-11-12 | Parkinson's Institute | Métodos y composiciones para la reducción de los efectos secundarios de tratamientos terapéuticos |
| CN101249130B (zh) * | 2008-04-11 | 2011-06-15 | 桂林商源植物制品有限公司 | 一种戒烟并缓解戒烟综合症的药用或保健组合物 |
| EP2729148A4 (en) | 2011-07-06 | 2015-04-22 | Parkinson S Inst | COMPOSITIONS AND METHOD FOR THE TREATMENT OF SYMPTOMS IN PATIENTS WITH MORBUS PARKINSON |
| JP2018511355A (ja) | 2015-01-28 | 2018-04-26 | クロノ セラピューティクス インコーポレイテッドＣｈｒｏｎｏ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． | 薬剤送達方法及びシステム |
| US10679516B2 (en) | 2015-03-12 | 2020-06-09 | Morningside Venture Investments Limited | Craving input and support system |
| US10568852B2 (en) | 2015-05-22 | 2020-02-25 | Helmholtz Zentrum Munchen - Deutsches Forschungszentrum Fur Gesundheit Und Umwelt (Gmbh) | Combination compositions and their use in methods for treating obesity and obesity-related disorders |
| CN105341990A (zh) * | 2015-12-16 | 2016-02-24 | 浙江中烟工业有限责任公司 | 一种提升电子烟生理满足感的电子烟烟液 |
| CA3049529A1 (en) | 2017-01-06 | 2018-07-12 | Chrono Therapeutics Inc. | Transdermal drug delivery devices and methods |
| US11596779B2 (en) | 2018-05-29 | 2023-03-07 | Morningside Venture Investments Limited | Drug delivery methods and systems |
| CA3119992A1 (en) | 2018-11-16 | 2020-05-22 | Morningside Venture Investments Limited | Thermally regulated transdermal drug delivery system |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5173585A (en) * | 1984-12-25 | 1986-07-03 | Tyroler, J. | Flavour capsule |
| AU5427586A (en) * | 1985-03-05 | 1986-10-16 | Ciba-Geigy Ag | Device and methods for treating memory impairment |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU432703A3 (cg-RX-API-DMAC7.html) * | 1971-08-24 | 1974-06-15 | Фридрих Боссерт, Вульф Фатер, Курт Бауер | |
| US3870794A (en) * | 1974-02-20 | 1975-03-11 | Foundation For Behavioral Rese | Treatment of certain emotional disorders with nicotine compounds |
| GB1528391A (en) * | 1976-01-05 | 1978-10-11 | Gildemeister V | Aerosol compositions |
| DE3241437A1 (de) * | 1982-11-10 | 1984-05-10 | Ferdinand Prof. Dr.med. 6901 Wilhelmsfeld Schmidt | Mittel zum zwecke der raucherentwoehnung und/oder fuer nebenwirkungsfreien nikotingenuss bei suchtrauchern |
| GB8301659D0 (en) * | 1983-01-21 | 1983-02-23 | Leo Ab | Smoking substitutes |
| BE899037A (fr) * | 1984-02-29 | 1984-06-18 | Trenker Ady | Composition a sucer permettant de cesser de fumer |
| DE3438284A1 (de) * | 1984-10-16 | 1985-03-07 | Hans-Harald von 2400 Lübeck Tilly | Nikotinhaltiges depotpflaster |
-
1986
- 1986-11-18 DE DE19863645036 patent/DE3645036A1/de active Granted
- 1986-11-18 DE DE19863639418 patent/DE3639418A1/de active Granted
-
1987
- 1987-11-06 DE DE8787907302T patent/DE3776574D1/de not_active Expired - Fee Related
- 1987-11-06 BR BR8707879A patent/BR8707879A/pt not_active Application Discontinuation
- 1987-11-06 AU AU81712/87A patent/AU622101B2/en not_active Ceased
- 1987-11-06 WO PCT/DE1987/000507 patent/WO1988003803A1/de not_active Ceased
- 1987-11-06 AT AT87907302T patent/ATE72114T1/de not_active IP Right Cessation
- 1987-11-06 EP EP87907302A patent/EP0324794B1/de not_active Expired - Lifetime
- 1987-11-06 JP JP62506732A patent/JP2602043B2/ja not_active Expired - Lifetime
- 1987-11-18 CN CN87107852A patent/CN87107852A/zh active Pending
-
1988
- 1988-07-08 DK DK198803858A patent/DK173353B1/da not_active IP Right Cessation
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU5173585A (en) * | 1984-12-25 | 1986-07-03 | Tyroler, J. | Flavour capsule |
| AU5427586A (en) * | 1985-03-05 | 1986-10-16 | Ciba-Geigy Ag | Device and methods for treating memory impairment |
Also Published As
| Publication number | Publication date |
|---|---|
| ATE72114T1 (de) | 1992-02-15 |
| EP0324794A1 (de) | 1989-07-26 |
| CN87107852A (zh) | 1988-06-22 |
| DE3776574D1 (de) | 1992-03-12 |
| EP0324794B1 (de) | 1992-01-29 |
| DK385888A (da) | 1988-07-08 |
| BR8707879A (pt) | 1989-10-03 |
| JP2602043B2 (ja) | 1997-04-23 |
| DE3639418C2 (cg-RX-API-DMAC7.html) | 1989-08-03 |
| WO1988003803A1 (fr) | 1988-06-02 |
| DE3639418A1 (de) | 1988-06-09 |
| DE3645036A1 (de) | 1989-01-05 |
| AU8171287A (en) | 1988-06-16 |
| DK385888D0 (da) | 1988-07-08 |
| JPH02501304A (ja) | 1990-05-10 |
| DK173353B1 (da) | 2000-08-07 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |