AU614497B2 - Factor viii-c analogs - Google Patents

Factor viii-c analogs Download PDF

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Publication number
AU614497B2
AU614497B2 AU79816/87A AU7981687A AU614497B2 AU 614497 B2 AU614497 B2 AU 614497B2 AU 79816/87 A AU79816/87 A AU 79816/87A AU 7981687 A AU7981687 A AU 7981687A AU 614497 B2 AU614497 B2 AU 614497B2
Authority
AU
Australia
Prior art keywords
cat
ccc
factor viii
analog
act
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
AU79816/87A
Other languages
English (en)
Other versions
AU7981687A (en
Inventor
William N. Dorhan
Nava Sarver
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rorer International Overseas Inc
Original Assignee
Rorer International Overseas Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rorer International Overseas Inc filed Critical Rorer International Overseas Inc
Publication of AU7981687A publication Critical patent/AU7981687A/en
Application granted granted Critical
Publication of AU614497B2 publication Critical patent/AU614497B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU79816/87A 1986-10-15 1987-10-14 Factor viii-c analogs Expired - Fee Related AU614497B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91915386A 1986-10-15 1986-10-15
US919153 1986-10-15

Publications (2)

Publication Number Publication Date
AU7981687A AU7981687A (en) 1988-04-21
AU614497B2 true AU614497B2 (en) 1991-09-05

Family

ID=25441601

Family Applications (1)

Application Number Title Priority Date Filing Date
AU79816/87A Expired - Fee Related AU614497B2 (en) 1986-10-15 1987-10-14 Factor viii-c analogs

Country Status (7)

Country Link
EP (1) EP0265778A1 (de)
JP (1) JPS6456696A (de)
AU (1) AU614497B2 (de)
DK (1) DK539587A (de)
FI (1) FI874546A (de)
IL (1) IL84168A0 (de)
NO (1) NO874292L (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
US5198349A (en) * 1986-01-03 1993-03-30 Genetics Institute, Inc. Method for producing factor VIII:C and analogs
US5595886A (en) * 1986-01-27 1997-01-21 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
US6060447A (en) * 1987-05-19 2000-05-09 Chiron Corporation Protein complexes having Factor VIII:C activity and production thereof
US6346513B1 (en) 1987-06-12 2002-02-12 Baxter Trading Gmbh Proteins with factor VIII activity: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
IE69026B1 (en) * 1987-06-12 1996-08-07 Immuno Ag Novel proteins with factor VIII activity process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
EP0294910B1 (de) * 1987-06-12 1996-09-11 Immuno Ag Proteine mit Faktor-VIII-Aktivität, Verfahren zu deren Herstellung unter Verwendung von genetisch modifizierten Zellen und diese enthaltende pharmazeutische Zusammensetzungen
FR2619314B1 (fr) * 1987-08-11 1990-06-15 Transgene Sa Analogue du facteur viii, procede de preparation et composition pharmaceutique le contenant
JP2810744B2 (ja) * 1989-07-04 1998-10-15 ノボ ノルディスク アクティーゼルスカブ F▲viii▼活性を有する蛋白質および/またはf▲viii▼誘導体の製造法
DK53792D0 (da) * 1992-04-24 1992-04-24 Novo Nordisk As Fremgangsmaade til fremstilling af proteiner
EP1707634A1 (de) 2005-03-29 2006-10-04 Octapharma AG Verfahren zur Isolierung von rekombinant hergestellten Proteinen
EP1739179A1 (de) 2005-06-30 2007-01-03 Octapharma AG Serumfreie stabile Transfektion und Produktion von rekombinanten humanen Proteinen in humanen Zelllinien
WO2011095604A1 (en) 2010-02-04 2011-08-11 Octapharma Biopharmaceuticals Gmbh Half-life prolongation of proteins
KR20140084208A (ko) 2011-10-18 2014-07-04 시에스엘 리미티드 정제된 인자 viii의 재구성 후의 안정성을 향상시키는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE122004000028I1 (de) * 1984-01-12 2004-09-30 Chiron Corp F}r Faktor-VIIIc kodierende DNA-Sequenzen und verwandte DNA-Konstruktionen.
ATE72838T1 (de) * 1985-04-12 1992-03-15 Genetics Inst Neue prokoagulierungsproteine.
IL83192A (en) * 1986-07-18 1992-11-15 Gist Brocades Nv Method for the preparation of proteins with factor viii activity by microbial host cells;expression vectors,host cells,antibodies

Also Published As

Publication number Publication date
FI874546A (fi) 1988-04-16
AU7981687A (en) 1988-04-21
IL84168A0 (en) 1988-03-31
FI874546A0 (fi) 1987-10-15
DK539587A (da) 1988-04-16
EP0265778A1 (de) 1988-05-04
DK539587D0 (da) 1987-10-15
NO874292D0 (no) 1987-10-14
JPS6456696A (en) 1989-03-03
NO874292L (no) 1988-04-18

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