AU596804B2 - A granular delayed-release form of pharmaceutically active substances - Google Patents

A granular delayed-release form of pharmaceutically active substances Download PDF

Info

Publication number
AU596804B2
AU596804B2 AU60685/86A AU6068586A AU596804B2 AU 596804 B2 AU596804 B2 AU 596804B2 AU 60685/86 A AU60685/86 A AU 60685/86A AU 6068586 A AU6068586 A AU 6068586A AU 596804 B2 AU596804 B2 AU 596804B2
Authority
AU
Australia
Prior art keywords
pharmaceutically active
release form
active substance
process according
granular
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU60685/86A
Other languages
English (en)
Other versions
AU6068586A (en
Inventor
Kimon Ventouras
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Haleon CH SARL
Original Assignee
Haleon CH SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haleon CH SARL filed Critical Haleon CH SARL
Publication of AU6068586A publication Critical patent/AU6068586A/en
Application granted granted Critical
Publication of AU596804B2 publication Critical patent/AU596804B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU60685/86A 1985-07-31 1986-07-30 A granular delayed-release form of pharmaceutically active substances Ceased AU596804B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8519310 1985-07-31
GB858519310A GB8519310D0 (en) 1985-07-31 1985-07-31 Granular active substances

Publications (2)

Publication Number Publication Date
AU6068586A AU6068586A (en) 1987-02-05
AU596804B2 true AU596804B2 (en) 1990-05-17

Family

ID=10583125

Family Applications (1)

Application Number Title Priority Date Filing Date
AU60685/86A Ceased AU596804B2 (en) 1985-07-31 1986-07-30 A granular delayed-release form of pharmaceutically active substances

Country Status (23)

Country Link
US (1) US4728513A (OSRAM)
JP (1) JPS6229514A (OSRAM)
AT (1) AT392901B (OSRAM)
AU (1) AU596804B2 (OSRAM)
BE (1) BE905200A (OSRAM)
CH (1) CH670566A5 (OSRAM)
DE (1) DE3625458A1 (OSRAM)
DK (1) DK361786A (OSRAM)
ES (1) ES2000577A6 (OSRAM)
FI (1) FI863074A7 (OSRAM)
FR (1) FR2585570B1 (OSRAM)
GB (2) GB8519310D0 (OSRAM)
GR (1) GR862017B (OSRAM)
HU (1) HU196304B (OSRAM)
IL (1) IL79537A (OSRAM)
IT (1) IT1195985B (OSRAM)
LU (1) LU86523A1 (OSRAM)
NL (1) NL8601961A (OSRAM)
NZ (1) NZ217028A (OSRAM)
PH (1) PH23531A (OSRAM)
PT (1) PT83093B (OSRAM)
SE (1) SE8603247L (OSRAM)
ZA (1) ZA865691B (OSRAM)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622254B2 (en) * 1989-01-03 1992-04-02 Sterling Drug Inc. Controlled-release, low dose aspirin

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4726952A (en) * 1983-08-11 1988-02-23 Mission Pharmacal Slow-release sodium fluoride tablet, method of making, and method of treatment of osteoporosis
JPH0830005B2 (ja) * 1985-09-25 1996-03-27 ゲルゲリイ、ゲルハルト 崩壊性錠剤とその製造方法
CH669523A5 (OSRAM) * 1986-06-25 1989-03-31 Mepha Ag
US4859467A (en) * 1986-09-25 1989-08-22 Colgate-Palmotive Company Sustained release fluoride composition
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
DE3712095A1 (de) * 1987-04-10 1988-10-20 Lentia Gmbh Bindemittelfreies granulat mit verzoegerter wirkstoffabgabe
US5178868A (en) * 1988-10-26 1993-01-12 Kabi Pharmacia Aktiebolaq Dosage form
IT1227899B (it) * 1988-12-23 1991-05-14 Poli Ind Chimica Spa Rivestimento totale o parziale di principi attivi farmaceutici e relative composizioni
US4970081A (en) * 1989-01-03 1990-11-13 Sterling Drug Inc. Controlled-release, low-dose aspirin formulation and method of treating vascular occlusive disease therewith
US5084287A (en) * 1990-03-15 1992-01-28 Warner-Lambert Company Pharmaceutically useful micropellets with a drug-coated core and controlled-release polymeric coat
US5013728A (en) * 1990-05-04 1991-05-07 Colgate - Palmolive Company Composition for treating osteoporosis and hormonal imbalance
US5153005A (en) * 1990-12-11 1992-10-06 Colgate-Palmolive Company Composition and method for preventing fluorosis
ES2109362T3 (es) 1991-06-21 1998-01-16 Univ Cincinnati Unas proteinas administrables oralmente y metodo para hacerlas.
US6613332B1 (en) 1991-06-21 2003-09-02 The University Of Cincinnati Oral administration of therapeutic proteins
US5266331A (en) * 1991-11-27 1993-11-30 Euroceltique, S.A. Controlled release oxycodone compositions
US5958459A (en) * 1991-12-24 1999-09-28 Purdue Pharma L.P. Opioid formulations having extended controlled released
US5273760A (en) * 1991-12-24 1993-12-28 Euroceltigue, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5286493A (en) * 1992-01-27 1994-02-15 Euroceltique, S.A. Stabilized controlled release formulations having acrylic polymer coating
US5968551A (en) * 1991-12-24 1999-10-19 Purdue Pharma L.P. Orally administrable opioid formulations having extended duration of effect
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US7070806B2 (en) * 1992-01-27 2006-07-04 Purdue Pharma Lp Controlled release formulations coated with aqueous dispersions of acrylic polymers
FI101039B (fi) * 1992-10-09 1998-04-15 Eeva Kristoffersson Menetelmä lääkepellettien valmistamiseksi
US20080075781A1 (en) * 1992-11-25 2008-03-27 Purdue Pharma Lp Controlled release oxycodone compositions
SG52402A1 (en) * 1992-12-22 1998-09-28 Univ Cincinnati Oral administration of immunologically active biomolecules and other therapeutic proteins
DE4319649A1 (de) * 1993-03-18 1994-09-22 Asta Medica Ag Feste Flupirtin enthaltende orale Darreichungsformen mit kontrollierter Wirkstoffabgabe
US20070275062A1 (en) * 1993-06-18 2007-11-29 Benjamin Oshlack Controlled release oxycodone compositions
US7740881B1 (en) 1993-07-01 2010-06-22 Purdue Pharma Lp Method of treating humans with opioid formulations having extended controlled release
IL110014A (en) * 1993-07-01 1999-11-30 Euro Celtique Sa Solid controlled-release oral dosage forms of opioid analgesics
US5879705A (en) * 1993-07-27 1999-03-09 Euro-Celtique S.A. Sustained release compositions of morphine and a method of preparing pharmaceutical compositions
US5843480A (en) * 1994-03-14 1998-12-01 Euro-Celtique, S.A. Controlled release diamorphine formulation
US20020006438A1 (en) * 1998-09-25 2002-01-17 Benjamin Oshlack Sustained release hydromorphone formulations exhibiting bimodal characteristics
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
FR2760190B1 (fr) * 1997-02-28 1999-04-09 Adir Composition pharmaceutique pour la liberation programmee de dexfenfluramine
WO1999001111A1 (en) 1997-07-02 1999-01-14 Euro-Celtique, S.A. Stabilized sustained release tramadol formulations
US6806294B2 (en) 1998-10-15 2004-10-19 Euro-Celtique S.A. Opioid analgesic
FR2785539B1 (fr) * 1998-11-06 2004-04-09 Prographarm Laboratoires Particules enrobees d'ibuprofene cristallin granule
DE19928312A1 (de) * 1999-06-16 2000-12-21 Schering Ag Arzneimittelzubereitung mit verzögerter Wirkstoffabgabe
DE60036874T2 (de) 1999-09-02 2008-06-26 Nostrum Pharmaceuticals Inc. Pellet formulierung mit gesteuerter freisetzung
ATE526950T1 (de) 1999-10-29 2011-10-15 Euro Celtique Sa Hydrocodon-formulierungen mit gesteuerter freisetzung
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
EP2283829A1 (en) 2000-10-30 2011-02-16 Euro-Celtique S.A. Controlled release hydrocodone formulations
US20110104214A1 (en) 2004-04-15 2011-05-05 Purdue Pharma L.P. Once-a-day oxycodone formulations
UA81224C2 (uk) * 2001-05-02 2007-12-25 Euro Celtic S A Дозована форма оксикодону та її застосування
US6884619B2 (en) 2001-07-17 2005-04-26 Yale University Inhibition of BEHAB cleavage and primary central nervous system (CNS) tumors
DE10152469A1 (de) * 2001-10-24 2003-06-26 Gruenenthal Gmbh 3-(3-Dimethylamino-1-ethyl-2-methyl-propyl)phenol enthaltendes Arzneimittel mit verzögerter Wirkstofffreisetzung
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
US7410965B2 (en) * 2002-05-29 2008-08-12 Gruenenthal Gmbh Delayed release pharmaceutical composition containing 1-dimethyl-amino-3-(3-methoxyphenyl)-2-methyl-pentan-3-ol
US20050100577A1 (en) * 2003-11-10 2005-05-12 Parker Theodore L. Expandable medical device with beneficial agent matrix formed by a multi solvent system
US7387793B2 (en) 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
US7611630B2 (en) * 2004-03-30 2009-11-03 Bend Research, Inc. Method and device for evaluation of pharmaceutical compositions
DE102004035938A1 (de) * 2004-07-23 2006-02-16 Röhm GmbH & Co. KG Verfahren zur Herstellung von überzogenen Arzneiformen mit stabilem Wirkstofffreigabeprofil
JPWO2006059716A1 (ja) * 2004-12-03 2008-06-05 武田薬品工業株式会社 固形製剤
EP2275088B2 (en) * 2005-02-25 2018-09-26 Takeda Pharmaceutical Company Limited Method for producing granules
US20080075768A1 (en) * 2006-07-21 2008-03-27 Vaughn Jason M Hydrophobic opioid abuse deterrent delivery system using opioid antagonists
DE102006051020A1 (de) * 2006-10-26 2008-04-30 Evonik Röhm Gmbh Verwendung von (Meth)acrylat-Copolymeren in Retard-Arzneiformen zur Verringerung des Einflusses von Ethanol auf die Wirkstofffreisetzung
US20100062073A1 (en) * 2006-11-29 2010-03-11 Ronald Arthur Beyerinck Pharmaceutical compositions comprising nanoparticles comprising enteric polymers casein
US20100119612A1 (en) * 2007-04-17 2010-05-13 Bend Research, Inc Nanoparticles comprising non-crystalline drug
WO2008135852A2 (en) * 2007-05-03 2008-11-13 Pfizer Products Inc. Pharmaceutical compositions comprising nanoparticles and casein
US8703204B2 (en) * 2007-05-03 2014-04-22 Bend Research, Inc. Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer
US8309129B2 (en) * 2007-05-03 2012-11-13 Bend Research, Inc. Nanoparticles comprising a drug, ethylcellulose, and a bile salt
US20080279930A1 (en) * 2007-05-07 2008-11-13 Bernd Terhaag Controlled-Release Flupirtine Compositions, Compacts, Kits and Methods of Making and Use Thereof
EP2162120B1 (en) * 2007-06-04 2016-05-04 Bend Research, Inc Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer
WO2008149230A2 (en) 2007-06-04 2008-12-11 Pfizer Products Inc. Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate
EP2178518A2 (en) * 2007-07-13 2010-04-28 Bend Research, Inc Nanoparticles comprising ionizable, poorly water soluble cellulosic polymers
US8765187B2 (en) * 2007-07-17 2014-07-01 Asahi Kasei Chemicals Corporation Aqueous composition
EP2240162A4 (en) * 2007-12-06 2013-10-09 Bend Res Inc NANOTE PARTICLES WITH A NON-IONIZABLE POLYMER AND AN AMIN-FUNCTIONALIZED METHACRYLATE COPOLYMER
EP2231169B1 (en) * 2007-12-06 2016-05-04 Bend Research, Inc. Pharmaceutical compositions comprising nanoparticles and a resuspending material
CN103432093B (zh) * 2013-08-31 2015-03-25 西南大学 甲磺酸普立地诺骨架缓释片及其制备方法
CA2936741C (en) 2014-10-31 2018-11-06 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4028785A (en) * 1984-03-23 1985-09-26 Ciba-Geigy Ag Storage-stable, quick disintegrating pressed shapes containing pharmaceutical active substances
AU5894486A (en) * 1985-06-24 1987-01-08 Novartis Ag Solid, stable dosage forms with an elastic film coating
AU6203386A (en) * 1985-08-29 1987-03-05 Zyma S.A. Controlled release tablet

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US904848A (en) * 1908-05-27 1908-11-24 William W Devore Artificial whirlpool.
AT64577B (de) * 1913-04-28 1914-04-25 Carl Georg Rodeck Volksbelustigungsvorrichtung mit sich drehenden Plattformen.
US1689138A (en) * 1927-10-15 1928-10-23 Playground & Gymnasium Equipme Bathers' inclined rotary water platform
NL280825A (OSRAM) * 1962-07-11
DE2010110A1 (de) * 1970-03-04 1971-09-16 Farbenfabriken Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung von Mikrokapseln mit Hilfe von synthetischen Koazervaten
DE2336218C3 (de) * 1973-07-17 1985-11-14 Byk Gulden Lomberg Chemische Fabrik Gmbh, 7750 Konstanz Orale Arzneiform
JPS52139715A (en) * 1976-05-14 1977-11-21 Nippon Kayaku Co Ltd Coated granules of alkali polyacrylate
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
JPS5867616A (ja) * 1981-10-15 1983-04-22 Tanabe Seiyaku Co Ltd 腸溶性マイクロカプセル
US4543886A (en) * 1983-03-09 1985-10-01 Intamin Inc. Amusement ride including a rotating loading terminal
DK62184D0 (da) * 1984-02-10 1984-02-10 Benzon As Alfred Diffusionsovertrukket polydepotpraeparat

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU4028785A (en) * 1984-03-23 1985-09-26 Ciba-Geigy Ag Storage-stable, quick disintegrating pressed shapes containing pharmaceutical active substances
AU5894486A (en) * 1985-06-24 1987-01-08 Novartis Ag Solid, stable dosage forms with an elastic film coating
AU6203386A (en) * 1985-08-29 1987-03-05 Zyma S.A. Controlled release tablet

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU622254B2 (en) * 1989-01-03 1992-04-02 Sterling Drug Inc. Controlled-release, low dose aspirin

Also Published As

Publication number Publication date
JPS6229514A (ja) 1987-02-07
IL79537A0 (en) 1986-10-31
GB2178313A (en) 1987-02-11
DK361786D0 (da) 1986-07-30
IT1195985B (it) 1988-11-03
HUT41630A (en) 1987-05-28
HU196304B (en) 1988-11-28
NL8601961A (nl) 1987-02-16
SE8603247D0 (sv) 1986-07-29
PT83093B (pt) 1989-01-30
CH670566A5 (OSRAM) 1989-06-30
ATA205686A (de) 1990-12-15
IT8648323A0 (it) 1986-07-29
LU86523A1 (fr) 1987-02-04
FR2585570A1 (fr) 1987-02-06
FI863074L (fi) 1987-02-01
DK361786A (da) 1987-02-01
GR862017B (en) 1986-12-23
NZ217028A (en) 1989-08-29
PH23531A (en) 1989-08-25
IL79537A (en) 1991-01-31
SE8603247L (sv) 1987-02-01
ZA865691B (en) 1987-03-25
FI863074A7 (fi) 1987-02-01
FR2585570B1 (fr) 1990-03-23
AU6068586A (en) 1987-02-05
BE905200A (fr) 1987-01-30
AT392901B (de) 1991-07-10
GB8519310D0 (en) 1985-09-04
FI863074A0 (fi) 1986-07-28
US4728513A (en) 1988-03-01
PT83093A (en) 1986-08-01
GB2178313B (en) 1989-08-23
ES2000577A6 (es) 1988-03-01
GB8618153D0 (en) 1986-09-03
DE3625458A1 (de) 1987-02-12

Similar Documents

Publication Publication Date Title
US4728513A (en) Granular delayed-release form of pharmaceutically active substances
US5283065A (en) Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
US4784858A (en) Controlled release tablet
CA1255223A (en) Pellet formulation
AU603624B2 (en) Galenical formulation
US4666703A (en) Storage-stable, quick-disintegrating pressed shapes containing pharmaceutical active substances
US5215758A (en) Controlled release matrix suppository for pharmaceuticals
US6576260B2 (en) Sustained-release form of administration containing tramadol saccharinate
KR880002673B1 (ko) 진통 캡슐제와 그 제조방법
KR101141508B1 (ko) 판토프라졸 복합 미립자 제형
GB2087235A (en) A granular delayed-release form of pharmaceutical active substances
CN103315965B (zh) 一种适用于婴幼儿及儿童的口服固体颗粒及其制备方法
BG65398B1 (bg) Ентерично покрит фармацевтичен състав и метод за получаване
US20100183730A1 (en) High dose composition of ursodeoxycholic acid
JP2004507487A (ja) 腸疾患治療薬
JPH03500288A (ja) 徐放性ニフェジピン製剤
CN106822907B (zh) 一种含消旋卡多曲的双相释放制剂及其制备方法
IE62643B1 (en) Synergistic combination of decarboxylase inhibitors and L-dopa pellets
GB2324962A (en) Chromone compositions for bio-availability to the small intestine
WO1998051300A1 (en) Treatment of allergic conditions
HU191102B (en) Process for producing pharmaceutical compositions of regulated dissolution of the active agents containing water-soluble inorganic pharmacons