AU5915100A - Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies - Google Patents
Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologiesInfo
- Publication number
- AU5915100A AU5915100A AU59151/00A AU5915100A AU5915100A AU 5915100 A AU5915100 A AU 5915100A AU 59151/00 A AU59151/00 A AU 59151/00A AU 5915100 A AU5915100 A AU 5915100A AU 5915100 A AU5915100 A AU 5915100A
- Authority
- AU
- Australia
- Prior art keywords
- glycation
- albumin
- treatment
- prevent
- related pathologies
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/40—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/42—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to carbon atoms of at least one six-membered aromatic ring and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton with carboxyl groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by saturated carbon chains
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/349,853 US6355680B1 (en) | 1996-02-20 | 1999-07-08 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
US09349853 | 1999-07-08 | ||
PCT/US2000/018449 WO2001003684A2 (en) | 1999-07-08 | 2000-07-06 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5915100A true AU5915100A (en) | 2001-01-30 |
Family
ID=23374238
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU59151/00A Abandoned AU5915100A (en) | 1999-07-08 | 2000-07-06 | Albumin-binding compounds that prevent nonenzymatic glycation and that may be used for treatment of glycation-related pathologies |
Country Status (9)
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU767724B2 (en) * | 2000-02-07 | 2003-11-20 | Novartis Ag | Dibenzo (B,F) azepine intermediates |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9922830D0 (en) * | 1999-09-27 | 1999-11-24 | Novartis Ag | Processes |
CA2420576C (en) * | 2000-08-29 | 2005-06-14 | Nobex Corporation | Immunoregulatory compounds, derivatives thereof and their use |
US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
US7220749B2 (en) | 2002-06-11 | 2007-05-22 | Nitromed, Inc. | Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use |
US7632866B2 (en) * | 2002-10-21 | 2009-12-15 | Ramot At Tel Aviv University | Derivatives of N-phenylanthranilic acid and 2-benzimidazolone as potassium channel and/or neuron activity modulators |
PE20040844A1 (es) * | 2002-11-26 | 2004-12-30 | Novartis Ag | Acidos fenilaceticos y derivados como inhibidores de la cox-2 |
PL1773767T3 (pl) | 2004-07-07 | 2016-07-29 | Biocon Ltd | Synteza azowo związanych związków immunoregulacyjnych |
JP2007275193A (ja) * | 2006-04-04 | 2007-10-25 | Fujifilm Corp | 光プローブおよび光断層画像化装置 |
AR061623A1 (es) | 2006-06-26 | 2008-09-10 | Novartis Ag | Derivados de acido fenilacetico |
US20080255236A1 (en) * | 2007-04-12 | 2008-10-16 | Glycadia, Inc. | Methods and Composition Comprising 2-[(3-Chlorophenyl)Amino] Phenylacetic Acid for Alzheimer's Disease |
CN101868443A (zh) * | 2007-09-20 | 2010-10-20 | 特拉维夫大学拉莫特有限公司 | N-苯基邻氨基苯甲酸衍生物及其用途 |
US20100035993A1 (en) * | 2008-08-06 | 2010-02-11 | Cohen Margo P | Methods and compositions comprising 2-[(3-chlorophenyl) amino] phenylacetic acid for hyperpermeability and neovascularization disorders of the retina |
WO2011090943A1 (en) * | 2010-01-22 | 2011-07-28 | Baylor College Of Medicine | Removal of pathological albumin from a subject's plasma |
US8962020B2 (en) * | 2012-07-26 | 2015-02-24 | Glycadia Inc. | Long-acting and controlled release formulations of 2-[(3-chlorophenyl) amino] phenylacetic acid |
EP4083029A1 (en) * | 2013-08-20 | 2022-11-02 | University of Washington through its Center for Commercialization | Novel and specific inhibitors of cytochrome p450 26 retinoic acid hydroxylase |
US20170157010A1 (en) * | 2015-12-08 | 2017-06-08 | Glycadia, Inc. | Methods and compositions for treatment of disorders associated with damage induced by free radicals |
CN109694330B (zh) * | 2017-10-24 | 2023-10-20 | 乳源瑶族自治县东阳光生物科技有限公司 | 一种酸的制备方法 |
CN107793323A (zh) * | 2017-11-23 | 2018-03-13 | 华中科技大学 | 一种双氯芬酸甲酯的合成方法 |
CN108047072A (zh) * | 2017-11-23 | 2018-05-18 | 深圳华中科技大学研究院 | 一种双氯芬酸钠的合成方法 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3558690A (en) * | 1965-04-08 | 1971-01-26 | Gelgy Chemical Corp | Substituted derivatives of 2-anilinophenylacetic acids and a process of preparation |
NL133740C (US20010034359A1-20011025-C00009.png) * | 1965-04-08 | |||
NO125724B (US20010034359A1-20011025-C00009.png) * | 1967-12-20 | 1972-10-23 | Ciba Geigy Ag | |
US3652762A (en) * | 1970-04-14 | 1972-03-28 | Ciba Geigy Corp | Pharmaceutical compositions and methods employing substituted derivatives of 2-anilinophenylacetic acids and esters |
NO134946C (US20010034359A1-20011025-C00009.png) * | 1970-09-09 | 1977-01-12 | Ciba Geigy Ag | |
JPS5259131A (en) * | 1975-11-10 | 1977-05-16 | Daito Koeki | Production of substituted phenyl acetic acids and salts |
JPS5283425A (en) * | 1975-12-30 | 1977-07-12 | Daito Koeki | Production of substituted anilinophenyl acetic acid |
DE3026402A1 (de) * | 1980-07-11 | 1982-02-04 | Syntex Corp., Palo Alto, Calif. | Die verwendung analgetischer und nicht-hormonaler, entzuendungshemmender mittel bei der behandlung von mikrovaskulaeren erkrankungen |
JPS5920256A (ja) * | 1982-07-27 | 1984-02-01 | Hokuriku Seiyaku Co Ltd | 2−(2,6−ジフルオロアニリノ)フエニル酢酸誘導体 |
US5223392A (en) * | 1988-01-25 | 1993-06-29 | Exocell, Inc. | Monoclonal antibodies against glycated albumin, hybrid cell lines producing these antibodies, and use therefore |
US5021576A (en) * | 1989-10-27 | 1991-06-04 | American Home Products Corporation | 2-Anilino phenylacetic acid derivatives |
IT1256345B (it) * | 1992-08-20 | 1995-12-01 | Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione | |
US5518720A (en) * | 1992-12-30 | 1996-05-21 | Exocell, Inc. | Treatment of complications of diabetes with substances reactive with the fructosyl-lysine structure in glycated albumin |
US5994401A (en) * | 1996-02-20 | 1999-11-30 | Exocell, Inc. | In Vivo Methods to reduce hypercholesterolemia and improve vascular dysfunction |
JP2002515031A (ja) * | 1996-02-20 | 2002-05-21 | エグゾセル・インコーポレーテッド | タンパク質グリコシル化の阻害および血管疾患の予防 |
JP2003119142A (ja) * | 1997-03-31 | 2003-04-23 | Mitsubishi Pharma Corp | 糖化蛋白変性物質生成阻害剤 |
-
1999
- 1999-07-08 US US09/349,853 patent/US6355680B1/en not_active Expired - Lifetime
-
2000
- 2000-07-06 KR KR1020077022640A patent/KR100817443B1/ko active IP Right Grant
- 2000-07-06 JP JP2001508965A patent/JP4833468B2/ja not_active Expired - Lifetime
- 2000-07-06 AU AU59151/00A patent/AU5915100A/en not_active Abandoned
- 2000-07-06 AT AT00945171T patent/ATE298568T1/de not_active IP Right Cessation
- 2000-07-06 DE DE60021113T patent/DE60021113T2/de not_active Expired - Lifetime
- 2000-07-06 EP EP00945171A patent/EP1242069B1/en not_active Expired - Lifetime
- 2000-07-06 KR KR1020027000280A patent/KR20020033725A/ko active Application Filing
- 2000-07-06 CA CA2378456A patent/CA2378456C/en not_active Expired - Lifetime
- 2000-07-06 WO PCT/US2000/018449 patent/WO2001003684A2/en active IP Right Grant
-
2001
- 2001-03-27 US US09/817,940 patent/US6552077B2/en not_active Expired - Lifetime
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU767724B2 (en) * | 2000-02-07 | 2003-11-20 | Novartis Ag | Dibenzo (B,F) azepine intermediates |
Also Published As
Publication number | Publication date |
---|---|
KR100817443B1 (ko) | 2008-03-27 |
JP2003504328A (ja) | 2003-02-04 |
JP4833468B2 (ja) | 2011-12-07 |
KR20020033725A (ko) | 2002-05-07 |
ATE298568T1 (de) | 2005-07-15 |
DE60021113T2 (de) | 2006-06-01 |
US6355680B1 (en) | 2002-03-12 |
WO2001003684A2 (en) | 2001-01-18 |
EP1242069B1 (en) | 2005-06-29 |
US6552077B2 (en) | 2003-04-22 |
CA2378456C (en) | 2012-04-10 |
KR20070104478A (ko) | 2007-10-25 |
US20010034359A1 (en) | 2001-10-25 |
CA2378456A1 (en) | 2001-01-18 |
DE60021113D1 (de) | 2005-08-04 |
WO2001003684A3 (en) | 2002-06-06 |
EP1242069A2 (en) | 2002-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |