AU586988B2 - Solid drug formulations and stable suspensions - Google Patents

Solid drug formulations and stable suspensions

Info

Publication number
AU586988B2
AU586988B2 AU49344/85A AU4934485A AU586988B2 AU 586988 B2 AU586988 B2 AU 586988B2 AU 49344/85 A AU49344/85 A AU 49344/85A AU 4934485 A AU4934485 A AU 4934485A AU 586988 B2 AU586988 B2 AU 586988B2
Authority
AU
Australia
Prior art keywords
stable suspensions
solid drug
drug formulations
suspensions
stable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU49344/85A
Other languages
English (en)
Other versions
AU4934485A (en
Inventor
Leo Geller
Peter Glanzmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of AU4934485A publication Critical patent/AU4934485A/en
Application granted granted Critical
Publication of AU586988B2 publication Critical patent/AU586988B2/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Request to Amend Deed and Register Assignors: CIBA-GEIGY AG
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
AU49344/85A 1984-11-06 1985-11-04 Solid drug formulations and stable suspensions Expired AU586988B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH530584 1984-11-06
CH5305/84 1984-11-06

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU41504/89A Division AU633844B2 (en) 1984-11-06 1989-09-18 Micronised drug formulation

Publications (2)

Publication Number Publication Date
AU4934485A AU4934485A (en) 1986-05-15
AU586988B2 true AU586988B2 (en) 1989-08-03

Family

ID=4291364

Family Applications (2)

Application Number Title Priority Date Filing Date
AU49344/85A Expired AU586988B2 (en) 1984-11-06 1985-11-04 Solid drug formulations and stable suspensions
AU41504/89A Expired AU633844B2 (en) 1984-11-06 1989-09-18 Micronised drug formulation

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU41504/89A Expired AU633844B2 (en) 1984-11-06 1989-09-18 Micronised drug formulation

Country Status (26)

Country Link
US (1) US5002940A (no)
EP (2) EP0346953B1 (no)
JP (2) JPS61204118A (no)
KR (1) KR890000907B1 (no)
AT (2) ATE84718T1 (no)
AU (2) AU586988B2 (no)
CA (1) CA1249223A (no)
CY (2) CY1898A (no)
DD (1) DD244292A5 (no)
DE (2) DE3587020D1 (no)
DK (1) DK162510C (no)
ES (1) ES8701491A1 (no)
FI (1) FI85809C (no)
GR (1) GR852637B (no)
HK (2) HK101192A (no)
HU (1) HU195728B (no)
IE (2) IE63156B1 (no)
IL (1) IL76943A (no)
MX (1) MX9203371A (no)
NL (1) NL940015I2 (no)
NO (1) NO169324C (no)
NZ (2) NZ229276A (no)
PH (1) PH21673A (no)
PT (1) PT81429B (no)
SG (1) SG107192G (no)
ZA (1) ZA858481B (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH673395A5 (no) * 1987-01-30 1990-03-15 Ciba Geigy Ag
MX9201782A (es) * 1991-04-19 1992-10-01 Sandoz Ag Particulas de sustancias biologicamente activas, sustancialmente insolubles en agua, proceso para su produccion y composicion farmaceutica que las contiene.
CH683151A5 (de) * 1991-04-24 1994-01-31 Ciba Geigy Ag Antikonzeption bei weiblichen Primaten ohne Beeinflussung des menstruellen Zyklus.
GB2344520A (en) * 1998-12-08 2000-06-14 Phares Pharm Res Nv Pharmaceutical carriers comprising lipids and polymers
JP2002532389A (ja) * 1998-12-08 2002-10-02 ファレス ファーマシューティカル リサーチ エヌブイ リン脂質組成物
US6447806B1 (en) 1999-02-25 2002-09-10 Novartis Ag Pharmaceutical compositions comprised of stabilized peptide particles
US6487907B1 (en) * 1999-07-08 2002-12-03 California Institute Of Technology Microgyroscope with integrated vibratory element
US20050100608A1 (en) * 2003-02-21 2005-05-12 Watson Pharmaceuticals, Inc. Testosterone oral dosage formulations and associated methods
ITMI20032054A1 (it) * 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
WO2009026473A2 (en) * 2007-08-21 2009-02-26 Hollis-Eden Pharmaceuticals, Inc. Stabilized therapeutic compositions and formulations
WO2019213286A1 (en) * 2018-05-02 2019-11-07 LifeMax Laboratories, Inc. Extended release suspension formulation of lurasidone

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226021A1 (de) * 1985-12-12 1987-06-24 BBC Brown Boveri AG Thyristor mit schaltbarem Emitter-Kurzschluss

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2068447A1 (en) * 1969-11-26 1971-08-27 Orsymonde Dehydrated pharmaceutical comps by - lyophilisation
LU77457A1 (no) * 1977-05-31 1979-01-19
US4235893A (en) * 1978-05-08 1980-11-25 Brodie Angela M Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
US4391755A (en) * 1982-01-18 1983-07-05 E. R. Squibb & Sons, Inc. Steroid monohydrates, formulations containing same and method
JPS58206513A (ja) * 1982-05-28 1983-12-01 Eisai Co Ltd セクレチン吸着防止組成物および方法
DE3225706C2 (de) * 1982-07-09 1984-04-26 A. Nattermann & Cie GmbH, 5000 Köln Flüssige Wirkstofformulierungen in Form von Konzentraten für Mikroemulsionen
DE3339295A1 (de) * 1982-11-15 1984-05-17 Schering AG, 1000 Berlin und 4709 Bergkamen 4-hydroxy- und 4-acyloxy-4-androsten-3,17-dione zur verwendung bei der prophylaxe und therapie der prostatahyperplasie und diese enthaltende mittel fuer derartige verwendung
EP0117811A3 (fr) * 1983-02-23 1987-06-03 Sanofi S.A. Compositions pharmaceutiques antifongiques utilisables par voie orale

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0226021A1 (de) * 1985-12-12 1987-06-24 BBC Brown Boveri AG Thyristor mit schaltbarem Emitter-Kurzschluss

Also Published As

Publication number Publication date
PH21673A (en) 1988-01-13
ES548492A0 (es) 1986-12-01
NZ229276A (en) 1989-08-29
IE852755L (en) 1986-05-06
PT81429A (en) 1985-12-01
CY1677A (en) 1993-10-10
AU633844B2 (en) 1993-02-11
IE902490L (en) 1986-05-06
NO854403L (no) 1986-05-07
MX9203371A (es) 1992-09-01
IL76943A (en) 1990-02-09
CY1898A (en) 1985-10-31
ZA858481B (en) 1986-06-25
NL940015I2 (nl) 1997-01-06
EP0181287A3 (en) 1987-09-23
FI854330A (fi) 1986-05-07
EP0346953A3 (en) 1990-11-22
EP0181287A2 (de) 1986-05-14
DD244292A5 (de) 1987-04-01
CA1249223A (en) 1989-01-24
DK162510C (da) 1992-03-30
FI85809B (fi) 1992-02-28
IE63166B1 (en) 1995-03-22
NZ214069A (en) 1989-08-29
JPS61204118A (ja) 1986-09-10
SG107192G (en) 1992-12-24
NL940015I1 (nl) 1994-10-17
NO169324C (no) 1992-06-10
KR890000907B1 (ko) 1989-04-13
AU4934485A (en) 1986-05-15
HUT42936A (en) 1987-09-28
KR860003825A (ko) 1986-06-13
DE3587020D1 (de) 1993-03-04
EP0346953B1 (de) 1993-01-20
HK192095A (en) 1995-12-29
GR852637B (no) 1986-03-04
ES8701491A1 (es) 1986-12-01
DK162510B (da) 1991-11-11
AU4150489A (en) 1990-01-04
JPH0558410B2 (no) 1993-08-26
IE63156B1 (en) 1995-03-22
HU195728B (en) 1988-07-28
DE3576650D1 (de) 1990-04-26
HK101192A (en) 1992-12-24
ATE51152T1 (de) 1990-04-15
DK509485D0 (da) 1985-11-05
ATE84718T1 (de) 1993-02-15
PT81429B (pt) 1988-03-03
FI854330A0 (fi) 1985-11-04
US5002940A (en) 1991-03-26
NO169324B (no) 1992-03-02
EP0181287B1 (de) 1990-03-21
JPH0648945A (ja) 1994-02-22
DK509485A (da) 1986-05-07
FI85809C (fi) 1992-06-10
EP0346953A2 (de) 1989-12-20
JPH0768130B2 (ja) 1995-07-26

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