AU576815B2 - 7-oxo-prostacyclines - Google Patents
7-oxo-prostacyclinesInfo
- Publication number
- AU576815B2 AU576815B2 AU37624/85A AU3762485A AU576815B2 AU 576815 B2 AU576815 B2 AU 576815B2 AU 37624/85 A AU37624/85 A AU 37624/85A AU 3762485 A AU3762485 A AU 3762485A AU 576815 B2 AU576815 B2 AU 576815B2
- Authority
- AU
- Australia
- Prior art keywords
- stands
- hydrogen
- compounds
- benzoyl
- represent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000002861 (C1-C4) alkanoyl group Chemical group 0.000 abstract 1
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 210000001772 blood platelet Anatomy 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 229910052736 halogen Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 125000001412 tetrahydropyranyl group Chemical group 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Furan Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU84128A HU191264B (en) | 1984-01-13 | 1984-01-13 | Process for production of derivatives of 7-oxo-prostacyclin with selective biological effect |
| HU128/84 | 1984-01-13 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU3762485A AU3762485A (en) | 1985-07-18 |
| AU576815B2 true AU576815B2 (en) | 1988-09-08 |
Family
ID=10948057
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU37624/85A Ceased AU576815B2 (en) | 1984-01-13 | 1985-01-11 | 7-oxo-prostacyclines |
Country Status (12)
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU588761B2 (en) * | 1985-05-29 | 1989-09-21 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara | 7-OXO-PGI`` ephedrine salts and their pharmaceutical compositions and methods |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4808734A (en) * | 1986-12-01 | 1989-02-28 | Hoffmann-La Roche Inc. | 16-cycloalkyl-7-fluoro-prostacyclins |
| DE102004024504A1 (de) * | 2004-05-18 | 2006-02-16 | Bayer Healthcare Ag | Neue Cylopenta[b]benzofuran-Derivate und ihre Verwendung |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7809181A (en) * | 1980-09-18 | 1982-04-14 | Schering Aktiengesellschaft | 7-oxoprostacyclin derivatives and process for the preparation thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4178367A (en) * | 1977-02-21 | 1979-12-11 | Ono Pharmaceutical Co. Ltd. | Prostaglandin I2 analogues |
| US4330553A (en) * | 1979-11-12 | 1982-05-18 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. | 7-Oxo-PGI2 -derivatives and process for the preparation thereof and pharmaceutical compositions containing same |
| DE3308561A1 (de) * | 1983-03-08 | 1984-09-13 | Schering AG, 1000 Berlin und 4709 Bergkamen | 19,20-methylenprostacyclinderivate und verfahren zu ihrer herstellung |
-
1984
- 1984-01-13 HU HU84128A patent/HU191264B/hu not_active IP Right Cessation
- 1984-12-27 IL IL73945A patent/IL73945A/xx not_active IP Right Cessation
-
1985
- 1985-01-11 GR GR850078A patent/GR850078B/el unknown
- 1985-01-11 FI FI850123A patent/FI850123A0/fi not_active Application Discontinuation
- 1985-01-11 DK DK014985A patent/DK165920C/da not_active IP Right Cessation
- 1985-01-11 ES ES539474A patent/ES8605229A1/es not_active Expired
- 1985-01-11 AU AU37624/85A patent/AU576815B2/en not_active Ceased
- 1985-01-11 AT AT85104957T patent/ATE40359T1/de not_active IP Right Cessation
- 1985-01-11 SU SU853837051A patent/SU1376939A3/ru active
- 1985-01-11 EP EP85104957A patent/EP0163905B1/de not_active Expired
- 1985-01-14 US US06/691,340 patent/US4588713A/en not_active Expired - Fee Related
- 1985-04-18 JP JP60081510A patent/JPH0643413B2/ja not_active Expired - Lifetime
- 1985-06-13 SU SU853912355A patent/SU1421741A1/ru active
- 1985-12-16 ES ES549967A patent/ES8701153A1/es not_active Expired
-
1986
- 1986-01-17 SU SU864008367A patent/SU1424735A3/ru active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU7809181A (en) * | 1980-09-18 | 1982-04-14 | Schering Aktiengesellschaft | 7-oxoprostacyclin derivatives and process for the preparation thereof |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU588761B2 (en) * | 1985-05-29 | 1989-09-21 | Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara | 7-OXO-PGI`` ephedrine salts and their pharmaceutical compositions and methods |
Also Published As
| Publication number | Publication date |
|---|---|
| HUT35658A (en) | 1985-07-29 |
| EP0163905A1 (de) | 1985-12-11 |
| ATE40359T1 (de) | 1989-02-15 |
| EP0163905B1 (de) | 1989-01-25 |
| HU191264B (en) | 1987-01-28 |
| SU1424735A3 (ru) | 1988-09-15 |
| DK165920B (da) | 1993-02-08 |
| SU1376939A3 (ru) | 1988-02-23 |
| ES8701153A1 (es) | 1986-12-01 |
| FI850123A0 (fi) | 1985-01-11 |
| JPH0643413B2 (ja) | 1994-06-08 |
| AU3762485A (en) | 1985-07-18 |
| ES549967A0 (es) | 1986-12-01 |
| US4588713A (en) | 1986-05-13 |
| DK165920C (da) | 1993-06-28 |
| SU1421741A1 (ru) | 1988-09-07 |
| IL73945A (en) | 1988-05-31 |
| ES539474A0 (es) | 1986-04-01 |
| DK14985A (da) | 1985-07-14 |
| IL73945A0 (en) | 1985-03-31 |
| ES8605229A1 (es) | 1986-04-01 |
| GR850078B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1985-05-13 |
| DK14985D0 (da) | 1985-01-11 |
| JPS61243073A (ja) | 1986-10-29 |
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