ES8100273A1 - Procedimiento para la preparacion de nuevos derivados de alfa-(3,4-diclorofenil)-2-imidazolina-2-metanol y alfa-(3,4-diclorofenil)-1,4,5,6-tetrahidro-2-pirimidinametanol - Google Patents

Procedimiento para la preparacion de nuevos derivados de alfa-(3,4-diclorofenil)-2-imidazolina-2-metanol y alfa-(3,4-diclorofenil)-1,4,5,6-tetrahidro-2-pirimidinametanol

Info

Publication number
ES8100273A1
ES8100273A1 ES487629A ES487629A ES8100273A1 ES 8100273 A1 ES8100273 A1 ES 8100273A1 ES 487629 A ES487629 A ES 487629A ES 487629 A ES487629 A ES 487629A ES 8100273 A1 ES8100273 A1 ES 8100273A1
Authority
ES
Spain
Prior art keywords
imidazoline
tetrahydro
antisecretory compounds
image
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487629A
Other languages
English (en)
Other versions
ES487629A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of ES487629A0 publication Critical patent/ES487629A0/es
Publication of ES8100273A1 publication Critical patent/ES8100273A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/06—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/22—Radicals substituted by oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVDOS DE ALFA-(3, 4-DICLOROFENIL)-2-MIMIDAZOLINA-2-METANOL Y ALFA-(3, 4-DICLOROFENIL)-1, 4, 5, 6-TETRAHIDRO-2-PIRIMINAMETANOL. CONSISTE EN HACER REACCIONAR UNA SAL ACIDA DE UN ESTER DE ALQUILO INFERIOR DE UN ACIDO HIDROXI-3, 4-DICLOROBENCENO-ACETIMIDICO CON UN ALCANO-DIAMINA COMO LA 1-2-DIAMINOPROPANO, 2-METIL-1, 2-DIAMINOPROPANO, 2, 3-DIAMINOBUTANO O 1, 3-DIAMINOPROPANO EN UN DISOLVENTE DE ALCOHOL INFERIOR DURANTE UN TIEMPO COMPRENDIDO ENTRE DIEZ MINUTOS Y VEINTE HORAS A UNA TEMPERATURA DE 0GC HASTA REFLUJO, OBTENIENDOSE UN COMPUESTO DE FORMULA GENERAL: ANTISECRETORIO. *FORMULA*
ES487629A 1979-03-26 1980-01-11 Procedimiento para la preparacion de nuevos derivados de alfa-(3,4-diclorofenil)-2-imidazolina-2-metanol y alfa-(3,4-diclorofenil)-1,4,5,6-tetrahidro-2-pirimidinametanol Expired ES8100273A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/023,920 US4260626A (en) 1979-03-26 1979-03-26 Tetrahydro and imidazoline antisecretory compounds

Publications (2)

Publication Number Publication Date
ES487629A0 ES487629A0 (es) 1980-11-01
ES8100273A1 true ES8100273A1 (es) 1980-11-01

Family

ID=21817931

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487629A Expired ES8100273A1 (es) 1979-03-26 1980-01-11 Procedimiento para la preparacion de nuevos derivados de alfa-(3,4-diclorofenil)-2-imidazolina-2-metanol y alfa-(3,4-diclorofenil)-1,4,5,6-tetrahidro-2-pirimidinametanol

Country Status (21)

Country Link
US (1) US4260626A (es)
JP (1) JPS55130963A (es)
AT (1) AT374186B (es)
AU (1) AU528325B2 (es)
BE (1) BE882420A (es)
CA (1) CA1111038A (es)
CH (1) CH644107A5 (es)
DE (1) DE3004439A1 (es)
DK (1) DK155324C (es)
ES (1) ES8100273A1 (es)
FR (1) FR2452486A1 (es)
GB (1) GB2045240B (es)
IE (1) IE49231B1 (es)
IL (1) IL58934A (es)
IT (1) IT1143009B (es)
NL (1) NL7909348A (es)
NO (1) NO152090C (es)
NZ (1) NZ192405A (es)
PH (1) PH15349A (es)
SE (1) SE446983B (es)
ZA (1) ZA796743B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069481B (en) * 1980-02-13 1983-07-27 Farmos Oy Substituted imidazole derivatives
US6060076A (en) * 1981-10-26 2000-05-09 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US6331308B1 (en) 1981-10-26 2001-12-18 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
US5925368A (en) * 1981-10-26 1999-07-20 Battelle Memorial Institute Protection of wooden objects in direct contact with soil from pest invasion
US6099850A (en) * 1981-10-26 2000-08-08 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US5272167A (en) * 1986-12-10 1993-12-21 Schering Corporation Pharmaceutically active compounds
US6852328B1 (en) 1989-09-01 2005-02-08 Battelle Memorial Institute K1-53 Method and device for protection of wooden objects proximate soil from pest invasion
US6319511B1 (en) 1989-09-01 2001-11-20 Battelle Memorial Institute Termite and boring insect barrier for the protection of wooden structures
US6572872B2 (en) 1989-09-01 2003-06-03 Battelle Memorial Institute Method and apparatus for providing long term protection from intrusion by insects and other cold blooded animals
CA2027530C (en) * 1989-10-20 2001-05-08 Jules Freedman W-phenoxy-heterocyclic compounds
US5134154A (en) * 1989-10-20 1992-07-28 Merrell Dow Pharmaceuticals Inc. Phenoxy-heterocyclic compounds
US5985304A (en) * 1998-02-25 1999-11-16 Battelle Memorial Institute Barrier preventing wood pest access to wooden structures
US20020192259A1 (en) * 1998-02-25 2002-12-19 Voris Peter Van Barrier preventing wood pest access to wooden structures
US20060201053A1 (en) * 2000-12-03 2006-09-14 Voris Peter V Barrier preventing wood pest access to wooden structures
US8075910B2 (en) * 2004-05-20 2011-12-13 Pbm Pharmaceuticals, Inc. Oral compositions comprising edible oils and vitamins and/or minerals and methods for making oral compositions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2919274A (en) * 1957-09-17 1959-12-29 Sahyun Melville Amidines
US3657229A (en) * 1968-05-02 1972-04-18 Sterling Drug Inc 1 3-diaza-2 3-cycloalkene derivatives
US3897431A (en) * 1969-04-24 1975-07-29 Sterling Drug Inc 2-{8 {60 -Alkoxy-arylmethyl{9 -2-imidazolines and -1,4,5,6-tetrahydropyrimidines
US3965112A (en) * 1971-01-11 1976-06-22 John Wyeth & Brother Limited Imidazoline derivatives
CA1010448A (en) 1971-01-11 1977-05-17 John Wyeth And Brother Limited Tetrahydropyrimidine, imidazoline and tetrahydro-1,3-diazepine derivatives
ZA718536B (en) * 1971-01-11 1972-09-27 Wyeth John & Brother Ltd Heterocyclic compounds
US3996207A (en) * 1971-01-11 1976-12-07 John Wyeth & Brother Limited Derivatives of tetrahydro-1H-1,3-diazepine and hexahydro-1,3-diazocine
US3998842A (en) * 1971-01-11 1976-12-21 John Wyeth & Brother Limited Diazepino[1,2-α]indoles
US3926994A (en) * 1971-01-11 1975-12-16 Wyeth John & Brother Ltd Heterocyclic compounds
ZA727999B (en) * 1971-12-06 1973-08-29 Wyeth John & Brother Ltd Derivatives of tetrahydropyrimidine,imidazoline and tetrahydro-1,3-diazepine
FR2207706B1 (es) * 1972-11-24 1975-11-28 Orsymonde
GB1538097A (en) * 1976-01-26 1979-01-10 Lafon Labor Substituted phenyl-amidines

Also Published As

Publication number Publication date
DE3004439C2 (es) 1989-05-24
DE3004439A1 (de) 1980-12-11
PH15349A (en) 1982-12-02
US4260626A (en) 1981-04-07
NO152090B (no) 1985-04-22
DK155324C (da) 1989-09-11
GB2045240B (en) 1982-12-22
ATA144780A (de) 1983-08-15
AT374186B (de) 1984-03-26
ZA796743B (en) 1980-11-26
ES487629A0 (es) 1980-11-01
IL58934A (en) 1984-05-31
GB2045240A (en) 1980-10-29
IT1143009B (it) 1986-10-22
SE446983B (sv) 1986-10-20
NO152090C (no) 1985-07-31
DK101980A (da) 1980-09-27
NO800857L (no) 1980-09-29
DK155324B (da) 1989-03-28
BE882420A (fr) 1980-07-16
NZ192405A (en) 1984-07-06
JPH0212949B2 (es) 1990-03-30
AU528325B2 (en) 1983-04-21
JPS55130963A (en) 1980-10-11
FR2452486A1 (fr) 1980-10-24
FR2452486B1 (es) 1983-09-16
IE49231B1 (en) 1985-09-04
SE8002293L (sv) 1980-09-27
IE792387L (en) 1980-09-26
CA1111038A (en) 1981-10-20
CH644107A5 (de) 1984-07-13
IT8047680A0 (it) 1980-01-23
AU5472880A (en) 1980-10-02
NL7909348A (nl) 1980-09-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303