AU575574B2 - Dimeric (spirofuran - pyran) derivatives - Google Patents

Dimeric (spirofuran - pyran) derivatives

Info

Publication number
AU575574B2
AU575574B2 AU31246/84A AU3124684A AU575574B2 AU 575574 B2 AU575574 B2 AU 575574B2 AU 31246/84 A AU31246/84 A AU 31246/84A AU 3124684 A AU3124684 A AU 3124684A AU 575574 B2 AU575574 B2 AU 575574B2
Authority
AU
Australia
Prior art keywords
spirofuran
dimeric
pyran
derivatives
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU31246/84A
Other languages
English (en)
Other versions
AU3124684A (en
Inventor
Chao-Min Liu
John Westley
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU3124684A publication Critical patent/AU3124684A/en
Application granted granted Critical
Publication of AU575574B2 publication Critical patent/AU575574B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/46Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/54Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being bound directly to a nitrogen atom of two or more radicals, e.g. streptomycin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/445The saccharide radical is condensed with a heterocyclic radical, e.g. everninomycin, papulacandin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/44Preparation of O-glycosides, e.g. glucosides
    • C12P19/60Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465Streptomyces
    • C12R2001/55Streptomyces hygroscopicus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Fodder In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU31246/84A 1983-07-28 1984-07-27 Dimeric (spirofuran - pyran) derivatives Ceased AU575574B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US518233 1983-07-28
US06/518,233 US4510317A (en) 1983-07-28 1983-07-28 Antibiotic X-14934A

Publications (2)

Publication Number Publication Date
AU3124684A AU3124684A (en) 1985-01-31
AU575574B2 true AU575574B2 (en) 1988-08-04

Family

ID=24063126

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31246/84A Ceased AU575574B2 (en) 1983-07-28 1984-07-27 Dimeric (spirofuran - pyran) derivatives

Country Status (21)

Country Link
US (1) US4510317A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0133971B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS6051198A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR910005629B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE33390T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (1) AU575574B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1253097A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3470313D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK159452C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES534644A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI76836C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR82437B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
HU (1) HU193017B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE57274B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL72517A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
MC (1) MC1615A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO158881C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ209022A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PH (1) PH20120A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT78991B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA845601B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4707493A (en) * 1983-02-15 1987-11-17 Pfizer Inc. 19-epi-dianemycin as an anticoccidial and antibacterial agent
US4591559A (en) * 1983-07-28 1986-05-27 Hoffmann-La Roche Inc. Antibiotic X-14934A and a method for its preparation
US4625041A (en) * 1984-02-17 1986-11-25 Pfizer Inc. Acidic polycyclic ether antibiotic
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DE3677844D1 (de) * 1985-05-28 1991-04-11 Lilly Co Eli Polyether-antibiotikum und verfahren zu seiner herstellung.
US5888788A (en) * 1994-05-18 1999-03-30 Union Nationale Des Groupements De Distillateurs D'alcool (Ungda) Use of ionophoretic polyether antibiotics for controlling bacterial growth in alcoholic fermentation
TW393413B (en) * 1996-01-19 2000-06-11 Shimano Kk Clipless bicycle pedal with large shoe-contacting area
WO2013138563A1 (en) * 2012-03-16 2013-09-19 University Of Geogia Research Foundation, Inc. Glycomimetics to inhibit pathogen-host interactions

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8615582A (en) * 1981-07-20 1983-02-03 Pfizer Inc. Polycyclic ether antibiotic cp-53,607 and animal feed compositions
AU2457284A (en) * 1983-02-15 1984-08-23 Pfizer Inc. 19-epi-dianemycin
AU3875985A (en) * 1984-02-17 1985-08-22 Pfizer Inc. Polycyclic ether antibiotic

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953474A (en) * 1974-11-15 1976-04-27 Eli Lilly And Company Antibiotic A204I derivatives
GB2024806B (en) * 1978-03-16 1982-05-06 Taisho Pharmaceutical Co Ltd Onomycin derivatives
JPS5592387A (en) * 1978-12-29 1980-07-12 Taisho Pharmaceut Co Ltd Antibiotic substance tm-531
FR2463144A1 (fr) * 1979-08-13 1981-02-20 Syntex Inc Nouveaux diesters de laidlomycine, leur procede de production, compositions a usage veterinaire les contenant et leur utilisation pour accroitre le rendement d'assimilation des aliments chez un ruminant
US4431665A (en) * 1979-08-13 1984-02-14 Syntex (U.S.A.) Inc. Acylated laidlomycin derivatives
EP0048585A1 (en) * 1980-09-16 1982-03-31 Taisho Pharmaceutical Co. Ltd Antibiotics TM-531 B and TM-531 C
GB2113671A (en) * 1982-01-19 1983-08-10 Pfizer Ltd Polycyclic ether antibiotics

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU8615582A (en) * 1981-07-20 1983-02-03 Pfizer Inc. Polycyclic ether antibiotic cp-53,607 and animal feed compositions
AU2457284A (en) * 1983-02-15 1984-08-23 Pfizer Inc. 19-epi-dianemycin
AU3875985A (en) * 1984-02-17 1985-08-22 Pfizer Inc. Polycyclic ether antibiotic

Also Published As

Publication number Publication date
NO158881B (no) 1988-08-01
NO158881C (no) 1988-11-09
PH20120A (en) 1986-10-02
EP0133971A1 (de) 1985-03-13
US4510317A (en) 1985-04-09
IE841949L (en) 1985-01-28
FI843009L (fi) 1985-01-29
DK159452B (da) 1990-10-15
IL72517A0 (en) 1984-11-30
ZA845601B (en) 1985-03-27
FI76836B (fi) 1988-08-31
MC1615A1 (fr) 1985-07-18
HU193017B (en) 1987-08-28
JPS6051198A (ja) 1985-03-22
PT78991A (en) 1984-08-01
AU3124684A (en) 1985-01-31
CA1253097A (en) 1989-04-25
NZ209022A (en) 1987-08-31
GR82437B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-12-13
NO843054L (no) 1985-01-29
DK366084A (da) 1985-01-29
PT78991B (en) 1986-10-23
EP0133971B1 (de) 1988-04-06
DE3470313D1 (en) 1988-05-11
FI843009A0 (fi) 1984-07-27
ATE33390T1 (de) 1988-04-15
HUT36178A (en) 1985-08-28
ES8600640A1 (es) 1985-10-16
ES534644A0 (es) 1985-10-16
IL72517A (en) 1988-03-31
FI76836C (fi) 1988-12-12
DK366084D0 (da) 1984-07-26
KR910005629B1 (ko) 1991-08-01
IE57274B1 (en) 1992-07-01
DK159452C (da) 1991-03-18
KR850001291A (ko) 1985-03-18

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