AU571184B2 - Compositions and methods for treating circulation disorders using protoberberines - Google Patents

Compositions and methods for treating circulation disorders using protoberberines

Info

Publication number
AU571184B2
AU571184B2 AU17063/83A AU1706383A AU571184B2 AU 571184 B2 AU571184 B2 AU 571184B2 AU 17063/83 A AU17063/83 A AU 17063/83A AU 1706383 A AU1706383 A AU 1706383A AU 571184 B2 AU571184 B2 AU 571184B2
Authority
AU
Australia
Prior art keywords
protoberberines
compositions
methods
circulation disorders
treating circulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU17063/83A
Other languages
English (en)
Other versions
AU1706383A (en
Inventor
Peter R. Maroko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MAROKO PR
Original Assignee
MAROKO PR
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MAROKO PR filed Critical MAROKO PR
Publication of AU1706383A publication Critical patent/AU1706383A/en
Application granted granted Critical
Publication of AU571184B2 publication Critical patent/AU571184B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU17063/83A 1982-05-14 1983-05-13 Compositions and methods for treating circulation disorders using protoberberines Ceased AU571184B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37812282A 1982-05-14 1982-05-14
US378122 1982-05-14
US40988382A 1982-08-20 1982-08-20
US409883 1982-08-20

Publications (2)

Publication Number Publication Date
AU1706383A AU1706383A (en) 1983-12-02
AU571184B2 true AU571184B2 (en) 1988-04-14

Family

ID=27008080

Family Applications (1)

Application Number Title Priority Date Filing Date
AU17063/83A Ceased AU571184B2 (en) 1982-05-14 1983-05-13 Compositions and methods for treating circulation disorders using protoberberines

Country Status (11)

Country Link
EP (1) EP0108147B1 (enExample)
AU (1) AU571184B2 (enExample)
CA (1) CA1220139A (enExample)
DE (1) DE3377695D1 (enExample)
ES (1) ES8703871A1 (enExample)
GR (1) GR79223B (enExample)
IE (1) IE55519B1 (enExample)
IL (1) IL68690A0 (enExample)
IT (1) IT1173712B (enExample)
PT (1) PT76690B (enExample)
WO (1) WO1983003970A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100258849B1 (ko) * 1998-04-24 2000-08-01 박원배 약학적으로 유용한 프로토베르베린염 유도체 및프로토베르베린유도체와 이의 염
WO2003047505A2 (en) 2001-11-14 2003-06-12 Rutgers, The State University Topoisomerase poison agents
EP1453507B1 (en) 2001-11-14 2009-03-04 Rutgers, The State University Solubilized topoisomerase poison agents
ES2311639T3 (es) 2001-11-14 2009-02-16 Rutgers, The State University Agentes citotoxicos.
WO2003041660A2 (en) 2001-11-14 2003-05-22 Rutgers, The State University Solubilized topoisomerase poisons
US6992088B2 (en) 2002-08-09 2006-01-31 Rutgers, The State University Of New Jersey Nitro and amino substituted heterocycles as topoisomerase I targeting agents
AU2003268075A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted dibenzonaphthyridines as topoisomerase agents
WO2004014918A1 (en) 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted topoisomerase agents
EP1562593B1 (en) 2002-11-12 2014-07-16 Rutgers, The State University of New Jersey Topoisomerase-targeting agents
CN100441183C (zh) * 2005-08-29 2008-12-10 中国医学科学院皮肤病研究所 盐酸13-己基小檗碱和盐酸13-己基巴马汀制备治疗湿疹、皮炎和银屑病的药物用途
WO2010102219A1 (en) 2009-03-06 2010-09-10 Rutgers, The State University Of New Jersey Methylenedioxybenzo [i] phenanthridine derivatives used to treat cancer
EP2405755A4 (en) * 2009-03-11 2012-11-28 Xintria Pharmaceutical Corp Inc METHOD AND COMPOSITIONS FOR TREATING METABOLISM AND CARDIOVASCULAR DISEASES
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
US20140107505A1 (en) 2012-10-11 2014-04-17 Alon Marmor Determination of ventricular pressure and related values
EP3442979A4 (en) 2016-04-04 2019-12-18 Rutgers, the State University of New Jersey topoisomerase poisons

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129028C (enExample) * 1964-02-13
US3420834A (en) * 1964-11-13 1969-01-07 Roussel Uclaf 2,3-dimethoxy-berbines substituted in the 10 position and process
JPS4942700A (enExample) * 1972-08-25 1974-04-22
US3920665A (en) * 1972-10-19 1975-11-18 Kanebo Ltd Berbine compounds
JPS523397B2 (enExample) * 1972-11-20 1977-01-27
US3910938A (en) * 1973-01-27 1975-10-07 Kanebo Ltd Berbine derivatives
US4042592A (en) * 1974-05-08 1977-08-16 Kanebo, Ltd. Novel dibenzo[a,g]quinolizinium compounds
US4087426A (en) * 1976-08-16 1978-05-02 Research Corporation Oxybisberberine and a process for its production
SE426548B (sv) * 1978-12-05 1983-01-31 Haessle Ab Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer

Also Published As

Publication number Publication date
CA1220139A (en) 1987-04-07
ES8703871A1 (es) 1987-03-16
GR79223B (enExample) 1984-10-22
AU1706383A (en) 1983-12-02
PT76690B (en) 1986-03-19
DE3377695D1 (en) 1988-09-22
ES522754A0 (es) 1987-03-16
IL68690A0 (en) 1983-09-30
IE55519B1 (en) 1990-10-10
EP0108147B1 (en) 1988-08-17
IT8348294A1 (it) 1984-11-13
IT8348294A0 (it) 1983-05-13
IE831098L (en) 1983-11-14
PT76690A (en) 1983-06-01
WO1983003970A1 (en) 1983-11-24
EP0108147A4 (en) 1984-09-13
IT1173712B (it) 1987-06-24
EP0108147A1 (en) 1984-05-16

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired