DE3377695D1 - Use of a protoberberine alkaloid and composition containing same - Google Patents

Use of a protoberberine alkaloid and composition containing same

Info

Publication number
DE3377695D1
DE3377695D1 DE8383902149T DE3377695T DE3377695D1 DE 3377695 D1 DE3377695 D1 DE 3377695D1 DE 8383902149 T DE8383902149 T DE 8383902149T DE 3377695 T DE3377695 T DE 3377695T DE 3377695 D1 DE3377695 D1 DE 3377695D1
Authority
DE
Germany
Prior art keywords
composition containing
containing same
protoberberine alkaloid
protoberberine
alkaloid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8383902149T
Other languages
English (en)
Inventor
Peter R Maroko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE3377695D1 publication Critical patent/DE3377695D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8383902149T 1982-05-14 1983-05-13 Use of a protoberberine alkaloid and composition containing same Expired DE3377695D1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37812282A 1982-05-14 1982-05-14
US40988382A 1982-08-20 1982-08-20
PCT/US1983/000729 WO1983003970A1 (en) 1982-05-14 1983-05-13 Compounds, compositions and method of treatment for improving circulatory performance

Publications (1)

Publication Number Publication Date
DE3377695D1 true DE3377695D1 (en) 1988-09-22

Family

ID=27008080

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8383902149T Expired DE3377695D1 (en) 1982-05-14 1983-05-13 Use of a protoberberine alkaloid and composition containing same

Country Status (11)

Country Link
EP (1) EP0108147B1 (de)
AU (1) AU571184B2 (de)
CA (1) CA1220139A (de)
DE (1) DE3377695D1 (de)
ES (1) ES8703871A1 (de)
GR (1) GR79223B (de)
IE (1) IE55519B1 (de)
IL (1) IL68690A0 (de)
IT (1) IT1173712B (de)
PT (1) PT76690B (de)
WO (1) WO1983003970A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100258849B1 (ko) * 1998-04-24 2000-08-01 박원배 약학적으로 유용한 프로토베르베린염 유도체 및프로토베르베린유도체와 이의 염
JP4628675B2 (ja) 2001-11-14 2011-02-09 ラトガーズ，ザ ステイト ユニバーシティ 可溶化トポイソメラーゼ毒
DE60228484D1 (de) 2001-11-14 2008-10-02 Univ Rutgers Cytotoxische mittel
CA2467279A1 (en) 2001-11-14 2003-06-26 Edmond J. Lavoie Solubilized topoisomerase poison agents
ATE390923T1 (de) 2001-11-14 2008-04-15 Univ Rutgers Topoisomerase-giftmittel
US6992089B2 (en) 2002-08-09 2006-01-31 Rutgers, The University Of New Jersey Nitro and amino substituted topoisomerase agents
WO2004014862A1 (en) 2002-08-09 2004-02-19 Rutgers, The State University Nitro and amino substituted heterocycles as topoisomerase i targeting agents
AU2003265406A1 (en) 2002-08-09 2004-02-25 Edmond J. Lavoie Nitro and amino substituted topoisomerase agents
WO2004044174A2 (en) 2002-11-12 2004-05-27 Rutgers, The State University Topoisomerase-targeting agents
CN100441183C (zh) * 2005-08-29 2008-12-10 中国医学科学院皮肤病研究所 盐酸13-己基小檗碱和盐酸13-己基巴马汀制备治疗湿疹、皮炎和银屑病的药物用途
ES2401563T3 (es) 2009-03-06 2013-04-22 Rutgers, The State University Of New Jersey Derivados de metilendioxibenzo [I]fenantridina usados para tratar el cáncer
EP2405755A4 (de) * 2009-03-11 2012-11-28 Xintria Pharmaceutical Corp Inc Verfahren und zusammensetzungen zur behandlung von stoffwechsel- und herz-kreislauf-erkrankungen
WO2010127363A1 (en) 2009-05-01 2010-11-04 Rutgers, The State University Of New Jersey Toposiomerase inhibitors
US20140107505A1 (en) * 2012-10-11 2014-04-17 Alon Marmor Determination of ventricular pressure and related values
US11091498B2 (en) 2016-04-04 2021-08-17 Rutgers, The State University Of New Jersey Topoisomerase poisons

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL129028C (de) * 1964-02-13
US3420834A (en) * 1964-11-13 1969-01-07 Roussel Uclaf 2,3-dimethoxy-berbines substituted in the 10 position and process
JPS4942700A (de) * 1972-08-25 1974-04-22
US3920665A (en) * 1972-10-19 1975-11-18 Kanebo Ltd Berbine compounds
JPS523397B2 (de) * 1972-11-20 1977-01-27
US3910938A (en) * 1973-01-27 1975-10-07 Kanebo Ltd Berbine derivatives
US4042592A (en) * 1974-05-08 1977-08-16 Kanebo, Ltd. Novel dibenzo[a,g]quinolizinium compounds
US4087426A (en) * 1976-08-16 1978-05-02 Research Corporation Oxybisberberine and a process for its production
SE426548B (sv) * 1978-12-05 1983-01-31 Haessle Ab Fast farmaceutisk beredning innehallande en terapeutiskt effektiv hjertglykosid och en polymer

Also Published As

Publication number Publication date
EP0108147A1 (de) 1984-05-16
IT1173712B (it) 1987-06-24
EP0108147B1 (de) 1988-08-17
WO1983003970A1 (en) 1983-11-24
GR79223B (de) 1984-10-22
ES8703871A1 (es) 1987-03-16
IE55519B1 (en) 1990-10-10
ES522754A0 (es) 1987-03-16
CA1220139A (en) 1987-04-07
IE831098L (en) 1983-11-14
AU1706383A (en) 1983-12-02
IL68690A0 (en) 1983-09-30
IT8348294A0 (it) 1983-05-13
PT76690A (en) 1983-06-01
AU571184B2 (en) 1988-04-14
PT76690B (en) 1986-03-19
EP0108147A4 (de) 1984-09-13

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee