AU5607873A - Tetrahydrocarbazole derivatives - Google Patents

Tetrahydrocarbazole derivatives

Info

Publication number
AU5607873A
AU5607873A AU56078/73A AU5607873A AU5607873A AU 5607873 A AU5607873 A AU 5607873A AU 56078/73 A AU56078/73 A AU 56078/73A AU 5607873 A AU5607873 A AU 5607873A AU 5607873 A AU5607873 A AU 5607873A
Authority
AU
Australia
Prior art keywords
tetrahydrocarbazole
compound
ethoxycarbonyl
salt
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU56078/73A
Other languages
English (en)
Inventor
Helmut Biere
Olaf Loge
Clemens Rufer
Ekkehard Schillinger
Hanns Ahrens
Eberhard Schroeder
Wolfgang Losert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU5607873A publication Critical patent/AU5607873A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU56078/73A 1972-05-25 1973-05-24 Tetrahydrocarbazole derivatives Expired AU5607873A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722226703 DE2226703A1 (de) 1972-05-25 1972-05-25 Neue tetrahydrocarbazolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
AU5607873A true AU5607873A (en) 1974-11-28

Family

ID=5846530

Family Applications (1)

Application Number Title Priority Date Filing Date
AU56078/73A Expired AU5607873A (en) 1972-05-25 1973-05-24 Tetrahydrocarbazole derivatives

Country Status (12)

Country Link
JP (1) JPS4941367A (enExample)
AT (1) AT323155B (enExample)
AU (1) AU5607873A (enExample)
BE (1) BE800066A (enExample)
CA (1) CA1005062A (enExample)
CH (1) CH582144A5 (enExample)
CS (1) CS179416B2 (enExample)
DD (1) DD106170A5 (enExample)
DE (1) DE2226703A1 (enExample)
FR (1) FR2185414B1 (enExample)
GB (1) GB1436893A (enExample)
NL (1) NL7307313A (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
DE10164564B4 (de) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)
WO2004026116A2 (en) 2002-09-19 2004-04-01 The Regents Of The University Of California Use of etodoclac to treat hyperplasia
US20060074124A1 (en) 2003-09-12 2006-04-06 Andrew Napper Methods of treating a disorder
WO2005026112A2 (en) * 2003-09-12 2005-03-24 Elixir Pharmaceuticals, Inc. Methods of treating a disorder
TW200526668A (en) * 2003-10-02 2005-08-16 Salmedix Inc Substituted indole derivatives
CN104311472B9 (zh) * 2008-07-23 2020-03-17 艾尼纳制药公司 经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物
PL2342205T4 (pl) 2008-08-27 2016-12-30 Podstawione tricykliczne pochodne kwasowe jako antagoniści receptora S1P1 użyteczni w leczeniu zaburzeń autoimmunologicznych i zapalnych
EP2528894A1 (en) 2010-01-27 2012-12-05 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
CN105503882B (zh) 2010-03-03 2019-07-05 艾尼纳制药公司 制备s1p1受体调节剂及其晶体形式的方法
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
JP6838744B2 (ja) 2015-06-22 2021-03-03 アリーナ ファーマシューティカルズ, インコーポレイテッド S1P1レセプター関連障害における使用のための(R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸(化合物1)の結晶性L−アルギニン塩
CN110520124A (zh) 2017-02-16 2019-11-29 艾尼纳制药公司 用于治疗原发性胆汁性胆管炎的化合物和方法
KR20190113955A (ko) 2017-02-16 2019-10-08 아레나 파마슈티칼스, 인크. 장-외 증상을 갖는 염증성 장질환의 치료를 위한 화합물 및 방법
JP7397011B2 (ja) 2018-06-06 2023-12-12 アリーナ ファーマシューティカルズ, インコーポレイテッド S1p1受容体に関連する状態を治療する方法
EP3847158B1 (en) 2018-09-06 2026-06-24 Arena Pharmaceuticals, Inc. Compounds useful in the treatment of autoimmune and inflammatory disorders
CN114634442B (zh) * 2022-04-02 2023-10-13 内蒙古民族大学 一种四氢咔唑酮化合物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH586678A5 (enExample) * 1970-05-25 1977-04-15 Hoffmann La Roche
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
CA1005062A (en) 1977-02-08
CH582144A5 (enExample) 1976-11-30
JPS4941367A (enExample) 1974-04-18
FR2185414A1 (enExample) 1974-01-04
AT323155B (de) 1975-06-25
DD106170A5 (enExample) 1974-06-05
GB1436893A (en) 1976-05-26
DE2226703A1 (de) 1973-12-13
CS179416B2 (en) 1977-10-31
NL7307313A (enExample) 1973-11-27
BE800066A (fr) 1973-11-26
FR2185414B1 (enExample) 1976-08-13

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