AT323155B - Verfahren zur herstellung von neuen tetrahydrocarbazolderivaten und ihren salzen - Google Patents
Verfahren zur herstellung von neuen tetrahydrocarbazolderivaten und ihren salzenInfo
- Publication number
- AT323155B AT323155B AT449173A AT449173A AT323155B AT 323155 B AT323155 B AT 323155B AT 449173 A AT449173 A AT 449173A AT 449173 A AT449173 A AT 449173A AT 323155 B AT323155 B AT 323155B
- Authority
- AT
- Austria
- Prior art keywords
- salt
- preparation
- tetrahydrocarbazole derivatives
- new
- new tetrahydrocarbazole
- Prior art date
Links
- XKLNOVWDVMWTOB-UHFFFAOYSA-N 2,3,4,9-tetrahydro-1h-carbazole Chemical class N1C2=CC=CC=C2C2=C1CCCC2 XKLNOVWDVMWTOB-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19722226703 DE2226703A1 (de) | 1972-05-25 | 1972-05-25 | Neue tetrahydrocarbazolderivate und verfahren zu ihrer herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AT323155B true AT323155B (de) | 1975-06-25 |
Family
ID=5846530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT449173A AT323155B (de) | 1972-05-25 | 1973-05-23 | Verfahren zur herstellung von neuen tetrahydrocarbazolderivaten und ihren salzen |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4941367A (enExample) |
| AT (1) | AT323155B (enExample) |
| AU (1) | AU5607873A (enExample) |
| BE (1) | BE800066A (enExample) |
| CA (1) | CA1005062A (enExample) |
| CH (1) | CH582144A5 (enExample) |
| CS (1) | CS179416B2 (enExample) |
| DD (1) | DD106170A5 (enExample) |
| DE (1) | DE2226703A1 (enExample) |
| FR (1) | FR2185414B1 (enExample) |
| GB (1) | GB1436893A (enExample) |
| NL (1) | NL7307313A (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033797A1 (en) * | 1979-08-06 | 1981-08-19 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles, their preparation, pharmaceutical compositions containing same and their preparation, intermediates therefor and their preparation |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7151100B1 (en) | 1999-07-23 | 2006-12-19 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US7129262B2 (en) | 1999-07-23 | 2006-10-31 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US7105560B1 (en) | 1999-07-23 | 2006-09-12 | The Regents Of The University Of California | Use of etodolac in the treatment of multiple myeloma |
| US7361680B2 (en) | 1999-07-23 | 2008-04-22 | The Regents Of The University Of California | Indole compounds useful for the treatment of cancer |
| US6545034B1 (en) | 1999-07-23 | 2003-04-08 | The Regents Of The University Of California | Use of etodolac for the treatment of chronic lymphocytic leukemia |
| DE10164564B4 (de) * | 2001-12-14 | 2007-05-16 | Zentaris Gmbh | Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR) |
| WO2004026116A2 (en) | 2002-09-19 | 2004-04-01 | The Regents Of The University Of California | Use of etodoclac to treat hyperplasia |
| US20060074124A1 (en) | 2003-09-12 | 2006-04-06 | Andrew Napper | Methods of treating a disorder |
| WO2005026112A2 (en) * | 2003-09-12 | 2005-03-24 | Elixir Pharmaceuticals, Inc. | Methods of treating a disorder |
| TW200526668A (en) * | 2003-10-02 | 2005-08-16 | Salmedix Inc | Substituted indole derivatives |
| CN104311472B9 (zh) * | 2008-07-23 | 2020-03-17 | 艾尼纳制药公司 | 经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物 |
| PL2342205T4 (pl) | 2008-08-27 | 2016-12-30 | Podstawione tricykliczne pochodne kwasowe jako antagoniści receptora S1P1 użyteczni w leczeniu zaburzeń autoimmunologicznych i zapalnych | |
| EP2528894A1 (en) | 2010-01-27 | 2012-12-05 | Arena Pharmaceuticals, Inc. | Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof |
| CN105503882B (zh) | 2010-03-03 | 2019-07-05 | 艾尼纳制药公司 | 制备s1p1受体调节剂及其晶体形式的方法 |
| CA3002540C (en) | 2015-01-06 | 2023-11-07 | Arena Pharmaceuticals, Inc. | Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor |
| JP6838744B2 (ja) | 2015-06-22 | 2021-03-03 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｓ１Ｐ１レセプター関連障害における使用のための（Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸（化合物１）の結晶性Ｌ−アルギニン塩 |
| CN110520124A (zh) | 2017-02-16 | 2019-11-29 | 艾尼纳制药公司 | 用于治疗原发性胆汁性胆管炎的化合物和方法 |
| KR20190113955A (ko) | 2017-02-16 | 2019-10-08 | 아레나 파마슈티칼스, 인크. | 장-외 증상을 갖는 염증성 장질환의 치료를 위한 화합물 및 방법 |
| JP7397011B2 (ja) | 2018-06-06 | 2023-12-12 | アリーナ ファーマシューティカルズ， インコーポレイテッド | Ｓ１ｐ１受容体に関連する状態を治療する方法 |
| EP3847158B1 (en) | 2018-09-06 | 2026-06-24 | Arena Pharmaceuticals, Inc. | Compounds useful in the treatment of autoimmune and inflammatory disorders |
| CN114634442B (zh) * | 2022-04-02 | 2023-10-13 | 内蒙古民族大学 | 一种四氢咔唑酮化合物的制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH586678A5 (enExample) * | 1970-05-25 | 1977-04-15 | Hoffmann La Roche | |
| ZA715217B (en) * | 1970-08-20 | 1972-04-26 | Org Nv | Anti-inflammatory preparations |
-
1972
- 1972-05-25 DE DE19722226703 patent/DE2226703A1/de active Pending
-
1973
- 1973-04-17 DD DD17023273A patent/DD106170A5/xx unknown
- 1973-05-14 GB GB2279573A patent/GB1436893A/en not_active Expired
- 1973-05-16 CS CS350973A patent/CS179416B2/cs unknown
- 1973-05-17 CH CH707473A patent/CH582144A5/xx not_active IP Right Cessation
- 1973-05-23 AT AT449173A patent/AT323155B/de not_active IP Right Cessation
- 1973-05-24 AU AU56078/73A patent/AU5607873A/en not_active Expired
- 1973-05-25 CA CA172,234A patent/CA1005062A/en not_active Expired
- 1973-05-25 JP JP5848173A patent/JPS4941367A/ja active Pending
- 1973-05-25 BE BE131549A patent/BE800066A/xx unknown
- 1973-05-25 NL NL7307313A patent/NL7307313A/xx not_active Application Discontinuation
- 1973-05-25 FR FR7319087A patent/FR2185414B1/fr not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0033797A1 (en) * | 1979-08-06 | 1981-08-19 | American Home Products Corporation | 1-Hydroxyalkanamine tetrahydrocarbazoles, their preparation, pharmaceutical compositions containing same and their preparation, intermediates therefor and their preparation |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1005062A (en) | 1977-02-08 |
| CH582144A5 (enExample) | 1976-11-30 |
| JPS4941367A (enExample) | 1974-04-18 |
| FR2185414A1 (enExample) | 1974-01-04 |
| DD106170A5 (enExample) | 1974-06-05 |
| AU5607873A (en) | 1974-11-28 |
| GB1436893A (en) | 1976-05-26 |
| DE2226703A1 (de) | 1973-12-13 |
| CS179416B2 (en) | 1977-10-31 |
| NL7307313A (enExample) | 1973-11-27 |
| BE800066A (fr) | 1973-11-26 |
| FR2185414B1 (enExample) | 1976-08-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ELJ | Ceased due to non-payment of the annual fee |