CS179416B2 - Method for preparation of new derivatives of tetrahydrocarbazole. - Google Patents

Method for preparation of new derivatives of tetrahydrocarbazole.

Info

Publication number
CS179416B2
CS179416B2 CS350973A CS350973A CS179416B2 CS 179416 B2 CS179416 B2 CS 179416B2 CS 350973 A CS350973 A CS 350973A CS 350973 A CS350973 A CS 350973A CS 179416 B2 CS179416 B2 CS 179416B2
Authority
CS
Czechoslovakia
Prior art keywords
tetrahydrocarbazole
preparation
new derivatives
derivatives
new
Prior art date
Application number
CS350973A
Other languages
English (en)
Inventor
Helmut Biere
Clemens Rufer
Hanns Ahrens
Eberhard Schroeder
Wolfgang Losert
Olaf Loge
Ekkehard Schillinger
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of CS179416B2 publication Critical patent/CS179416B2/cs

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CS350973A 1972-05-25 1973-05-16 Method for preparation of new derivatives of tetrahydrocarbazole. CS179416B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722226703 DE2226703A1 (de) 1972-05-25 1972-05-25 Neue tetrahydrocarbazolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CS179416B2 true CS179416B2 (en) 1977-10-31

Family

ID=5846530

Family Applications (1)

Application Number Title Priority Date Filing Date
CS350973A CS179416B2 (en) 1972-05-25 1973-05-16 Method for preparation of new derivatives of tetrahydrocarbazole.

Country Status (12)

Country Link
JP (1) JPS4941367A (cs)
AT (1) AT323155B (cs)
AU (1) AU5607873A (cs)
BE (1) BE800066A (cs)
CA (1) CA1005062A (cs)
CH (1) CH582144A5 (cs)
CS (1) CS179416B2 (cs)
DD (1) DD106170A5 (cs)
DE (1) DE2226703A1 (cs)
FR (1) FR2185414B1 (cs)
GB (1) GB1436893A (cs)
NL (1) NL7307313A (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
DE10164564B4 (de) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)
US7211599B2 (en) 2002-09-19 2007-05-01 The Regents Of The University Of California Use of etodolac to treat hyperplasia
US20060074124A1 (en) 2003-09-12 2006-04-06 Andrew Napper Methods of treating a disorder
JP4908215B2 (ja) * 2003-09-12 2012-04-04 エリクサー ファーマスーティカルズ インコーポレイテッド 疾患の治療法
WO2005033113A2 (en) * 2003-10-02 2005-04-14 Cephalon, Inc Indole derivatives
CN102164891B (zh) 2008-07-23 2014-09-03 艾尼纳制药公司 可用于治疗自身免疫性疾病和炎性疾病的经取代的1,2,3,4-四氢环戊并[b]吲哚-3-基乙酸衍生物
CA2733671C (en) 2008-08-27 2018-01-02 Arena Pharmaceuticals, Inc. Substituted tricyclic acid derivatives as s1p1 receptor agonists useful in the treatment of autoimmune and inflammatory disorders
ES2937386T3 (es) 2010-01-27 2023-03-28 Arena Pharm Inc Procesos para la preparación de ácido (R)-2-(7-(4-ciclopentil-3-(trifluorometil)benciloxi)-1,2,3,4-tetrahidrociclopenta[b]indol-3-il)acético y sales del mismo
SG183416A1 (en) 2010-03-03 2012-09-27 Arena Pharm Inc Processes for the preparation of s1p1 receptor modulators and crystalline forms thereof
SI3242666T1 (sl) 2015-01-06 2025-03-31 Arena Pharmaceuticals, Inc. Spojina za uporabo pri zdravljenju stanj, povezanih z receptorjem s1p1
EP3939965A1 (en) 2015-06-22 2022-01-19 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in sipi receptor-associated disorders
MA47504A (fr) 2017-02-16 2019-12-25 Arena Pharm Inc Composés et méthodes de traitement de l'angiocholite biliaire primitive
JP2020507610A (ja) 2017-02-16 2020-03-12 アリーナ ファーマシューティカルズ， インコーポレイテッド 腸管外症状を伴う炎症性腸疾患の治療のための化合物および方法
MA52778A (fr) 2018-06-06 2021-04-21 Arena Pharm Inc Méthodes de traitement de troubles associés au récepteur s1p1
CN119751336A (zh) 2018-09-06 2025-04-04 艾尼纳制药公司 可用于治疗自身免疫性病症和炎性病症的化合物
CN114634442B (zh) * 2022-04-02 2023-10-13 内蒙古民族大学 一种四氢咔唑酮化合物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH586678A5 (cs) * 1970-05-25 1977-04-15 Hoffmann La Roche
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
AU5607873A (en) 1974-11-28
GB1436893A (en) 1976-05-26
JPS4941367A (cs) 1974-04-18
DE2226703A1 (de) 1973-12-13
FR2185414A1 (cs) 1974-01-04
CA1005062A (en) 1977-02-08
AT323155B (de) 1975-06-25
NL7307313A (cs) 1973-11-27
DD106170A5 (cs) 1974-06-05
BE800066A (fr) 1973-11-26
CH582144A5 (cs) 1976-11-30
FR2185414B1 (cs) 1976-08-13

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