CA1005062A - Process for producing tetrahydrocarbazole derivatives - Google Patents

Process for producing tetrahydrocarbazole derivatives

Info

Publication number
CA1005062A
CA1005062A CA172,234A CA172234A CA1005062A CA 1005062 A CA1005062 A CA 1005062A CA 172234 A CA172234 A CA 172234A CA 1005062 A CA1005062 A CA 1005062A
Authority
CA
Canada
Prior art keywords
producing
tetrahydrocarbazole derivatives
tetrahydrocarbazole
derivatives
producing tetrahydrocarbazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA172,234A
Other versions
CA172234S (en
Inventor
Helmut Biere
Clemens Rufer
Ekkehard Schillinger
Olaf Loge
Eberhard Schroder
Hanns Ahrens
Wolfgang Losert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1005062A publication Critical patent/CA1005062A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/86—Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CA172,234A 1972-05-25 1973-05-25 Process for producing tetrahydrocarbazole derivatives Expired CA1005062A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722226703 DE2226703A1 (en) 1972-05-25 1972-05-25 NEW TETRAHYDROCARBAZOLE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION

Publications (1)

Publication Number Publication Date
CA1005062A true CA1005062A (en) 1977-02-08

Family

ID=5846530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA172,234A Expired CA1005062A (en) 1972-05-25 1973-05-25 Process for producing tetrahydrocarbazole derivatives

Country Status (12)

Country Link
JP (1) JPS4941367A (en)
AT (1) AT323155B (en)
AU (1) AU5607873A (en)
BE (1) BE800066A (en)
CA (1) CA1005062A (en)
CH (1) CH582144A5 (en)
CS (1) CS179416B2 (en)
DD (1) DD106170A5 (en)
DE (1) DE2226703A1 (en)
FR (1) FR2185414B1 (en)
GB (1) GB1436893A (en)
NL (1) NL7307313A (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
DE10164564B4 (en) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazole derivatives as ligands for G-protein coupled receptors (GPCR)
WO2004026116A2 (en) 2002-09-19 2004-04-01 The Regents Of The University Of California Use of etodoclac to treat hyperplasia
US20060074124A1 (en) * 2003-09-12 2006-04-06 Andrew Napper Methods of treating a disorder
EP1677794B1 (en) * 2003-09-12 2014-12-03 Elixir Pharmaceuticals, Inc. Methods of treating disorder
US7314886B2 (en) 2003-10-02 2008-01-01 Cephalon, Inc. Tetrahydropyrano-indole derivatives
KR20190004843A (en) * 2008-07-23 2019-01-14 아레나 파마슈티칼스, 인크. SUBSTITUTED 1,2,3,4- TETRAHYDROCYCLOPENTA[b]INDOL-3-YL) ACETIC ACID DERIVATIVES USEFUL IN THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISORDERS
BRPI0917923B1 (en) 2008-08-27 2022-04-05 Arena Pharmaceuticals Inc Substituted tricyclic acid derivative, its composition, its use and process for preparing said composition
EP3378854B1 (en) 2010-01-27 2022-12-21 Arena Pharmaceuticals, Inc. Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
JP2013521301A (en) 2010-03-03 2013-06-10 アリーナ ファーマシューティカルズ， インコーポレイテッド Process for the preparation of S1P1 receptor modulators and their crystalline forms
CN116850181A (en) 2015-01-06 2023-10-10 艾尼纳制药公司 Treatment and S1P 1 Methods of receptor-related disorders
MX2017016530A (en) 2015-06-22 2018-03-12 Arena Pharm Inc Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluo romethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)a cetic acid(compound1) for use in sipi receptor-associated disorders.
US11478448B2 (en) 2017-02-16 2022-10-25 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of inflammatory bowel disease with extra-intestinal manifestations
CN110520124A (en) 2017-02-16 2019-11-29 艾尼纳制药公司 For treating the Compounds and methods for of primary biliary cholangitis
KR20210074291A (en) 2018-09-06 2021-06-21 아레나 파마슈티칼스, 인크. Compounds useful for the treatment of autoimmune and inflammatory disorders
CN114634442B (en) * 2022-04-02 2023-10-13 内蒙古民族大学 Preparation method of tetrahydrocarbazolone compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH586678A5 (en) * 1970-05-25 1977-04-15 Hoffmann La Roche
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
FR2185414A1 (en) 1974-01-04
GB1436893A (en) 1976-05-26
CH582144A5 (en) 1976-11-30
BE800066A (en) 1973-11-26
DE2226703A1 (en) 1973-12-13
CS179416B2 (en) 1977-10-31
FR2185414B1 (en) 1976-08-13
NL7307313A (en) 1973-11-27
DD106170A5 (en) 1974-06-05
AT323155B (en) 1975-06-25
AU5607873A (en) 1974-11-28
JPS4941367A (en) 1974-04-18

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