CA1005062A - Process for producing tetrahydrocarbazole derivatives - Google Patents

Process for producing tetrahydrocarbazole derivatives

Info

Publication number
CA1005062A
CA1005062A CA172,234A CA172234A CA1005062A CA 1005062 A CA1005062 A CA 1005062A CA 172234 A CA172234 A CA 172234A CA 1005062 A CA1005062 A CA 1005062A
Authority
CA
Canada
Prior art keywords
producing
tetrahydrocarbazole derivatives
tetrahydrocarbazole
derivatives
producing tetrahydrocarbazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA172,234A
Other languages
English (en)
Other versions
CA172234S (en
Inventor
Helmut Biere
Clemens Rufer
Ekkehard Schillinger
Olaf Loge
Eberhard Schroder
Hanns Ahrens
Wolfgang Losert
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of CA1005062A publication Critical patent/CA1005062A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
CA172,234A 1972-05-25 1973-05-25 Process for producing tetrahydrocarbazole derivatives Expired CA1005062A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19722226703 DE2226703A1 (de) 1972-05-25 1972-05-25 Neue tetrahydrocarbazolderivate und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
CA1005062A true CA1005062A (en) 1977-02-08

Family

ID=5846530

Family Applications (1)

Application Number Title Priority Date Filing Date
CA172,234A Expired CA1005062A (en) 1972-05-25 1973-05-25 Process for producing tetrahydrocarbazole derivatives

Country Status (12)

Country Link
JP (1) JPS4941367A (cs)
AT (1) AT323155B (cs)
AU (1) AU5607873A (cs)
BE (1) BE800066A (cs)
CA (1) CA1005062A (cs)
CH (1) CH582144A5 (cs)
CS (1) CS179416B2 (cs)
DD (1) DD106170A5 (cs)
DE (1) DE2226703A1 (cs)
FR (1) FR2185414B1 (cs)
GB (1) GB1436893A (cs)
NL (1) NL7307313A (cs)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235903A (en) * 1979-08-06 1980-11-25 American Home Products Corporation 1-Hydroxyalkanamine tetrahydrocarbazoles and cyclopent[b]indoles, compositions and method of use
US7361680B2 (en) 1999-07-23 2008-04-22 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US7105560B1 (en) 1999-07-23 2006-09-12 The Regents Of The University Of California Use of etodolac in the treatment of multiple myeloma
US7129262B2 (en) 1999-07-23 2006-10-31 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
US6545034B1 (en) 1999-07-23 2003-04-08 The Regents Of The University Of California Use of etodolac for the treatment of chronic lymphocytic leukemia
US7151100B1 (en) 1999-07-23 2006-12-19 The Regents Of The University Of California Indole compounds useful for the treatment of cancer
DE10164564B4 (de) * 2001-12-14 2007-05-16 Zentaris Gmbh Tetrahydrocarbazolderivate als Liganden für G-Protein gekoppelte Rezeptoren (GPCR)
AU2003295336A1 (en) 2002-09-19 2004-04-08 Dennis A. Carson Use of etodoclac to treat hyperplasia
US20060074124A1 (en) * 2003-09-12 2006-04-06 Andrew Napper Methods of treating a disorder
JP4908215B2 (ja) * 2003-09-12 2012-04-04 エリクサー ファーマスーティカルズ インコーポレイテッド 疾患の治療法
US7446122B2 (en) 2003-10-02 2008-11-04 Cephalon, Inc. Substituted indole derivatives
KR20220084423A (ko) * 2008-07-23 2022-06-21 아레나 파마슈티칼스, 인크. 자가면역성 및 염증성의 장애의 치료에 유용한 치환된 1,2,3,4-테트라히드로시클로펜타[b]인돌-3-일)아세트산 유도체
AU2009288738B9 (en) 2008-08-27 2015-04-16 Arena Pharmaceuticals, Inc. Substituted tricyclic acid derivatives as S1P1 receptor agonists useful in the treatment of autoimmune and inflammatory disorders
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ, インコーポレイテッド (R)−2−(7−(4−シクロペンチル−3−(トリフルオロメチル)ベンジルオキシ)−1,2,3,4−テトラヒドロシクロペンタ[b]インドール−3−イル)酢酸およびその塩の調製のためのプロセス
CA2789480A1 (en) 2010-03-03 2011-09-09 Arena Pharmaceuticals, Inc. Processes for the preparation of s1p1 receptor modulators and crystalline forms thereof
MX386419B (es) 2015-01-06 2025-03-18 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
EP3310760B8 (en) 2015-06-22 2022-10-19 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in s1p1 receptor-associated disorders
ES2981521T3 (es) 2017-02-16 2024-10-09 Arena Pharm Inc Compuestos y procedimientos para el tratamiento de la enfermedad inflamatoria intestinal con manifestaciones extraintestinales
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1
CN119751336A (zh) 2018-09-06 2025-04-04 艾尼纳制药公司 可用于治疗自身免疫性病症和炎性病症的化合物
CN114634442B (zh) * 2022-04-02 2023-10-13 内蒙古民族大学 一种四氢咔唑酮化合物的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH586678A5 (cs) * 1970-05-25 1977-04-15 Hoffmann La Roche
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
AU5607873A (en) 1974-11-28
BE800066A (fr) 1973-11-26
DD106170A5 (cs) 1974-06-05
CH582144A5 (cs) 1976-11-30
AT323155B (de) 1975-06-25
JPS4941367A (cs) 1974-04-18
CS179416B2 (en) 1977-10-31
NL7307313A (cs) 1973-11-27
FR2185414A1 (cs) 1974-01-04
GB1436893A (en) 1976-05-26
FR2185414B1 (cs) 1976-08-13
DE2226703A1 (de) 1973-12-13

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