AU536055B2 - Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole - Google Patents

Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole

Info

Publication number
AU536055B2
AU536055B2 AU53896/79A AU5389679A AU536055B2 AU 536055 B2 AU536055 B2 AU 536055B2 AU 53896/79 A AU53896/79 A AU 53896/79A AU 5389679 A AU5389679 A AU 5389679A AU 536055 B2 AU536055 B2 AU 536055B2
Authority
AU
Australia
Prior art keywords
benzthiadiazole
benzoxadiazole
derivatives
dihydropyridine
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU53896/79A
Other languages
English (en)
Other versions
AU5389679A (en
Inventor
Peter Neumann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of AU5389679A publication Critical patent/AU5389679A/en
Application granted granted Critical
Publication of AU536055B2 publication Critical patent/AU536055B2/en
Assigned to NOVARTIS AG reassignment NOVARTIS AG Request to Amend Deed and Register Assignors: SANDOZ LTD.
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU53896/79A 1978-12-18 1979-12-17 Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole Expired AU536055B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1283578A CH639659A5 (de) 1978-12-18 1978-12-18 Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.
CH12835/78 1978-12-18

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU79464/82A Division AU536069B2 (en) 1978-12-18 1982-01-12 An 1,4-dhydropyridine derivative, its preparation and pharmaceutical compositions containing it

Publications (2)

Publication Number Publication Date
AU5389679A AU5389679A (en) 1980-06-26
AU536055B2 true AU536055B2 (en) 1984-04-19

Family

ID=4386824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53896/79A Expired AU536055B2 (en) 1978-12-18 1979-12-17 Derivatives of 1,4 dihydropyridine substituted by benzoxadiazole or benzthiadiazole

Country Status (18)

Country Link
JP (1) JPS5583783A (cs)
AU (1) AU536055B2 (cs)
BE (1) BE880591A (cs)
CH (1) CH639659A5 (cs)
CY (1) CY1321A (cs)
DE (1) DE2949491A1 (cs)
FR (1) FR2444681A1 (cs)
GB (2) GB2103203B (cs)
HK (1) HK16086A (cs)
IE (1) IE49496B1 (cs)
IT (1) IT1164097B (cs)
KE (1) KE3593A (cs)
MY (1) MY8500130A (cs)
NL (2) NL193066C (cs)
NZ (1) NZ192422A (cs)
SE (1) SE445219B (cs)
SG (1) SG97585G (cs)
ZA (1) ZA796842B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
CH655658B (cs) * 1980-09-18 1986-05-15
EP0080220B1 (en) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
IL68975A (en) * 1982-06-15 1987-01-30 Sandoz Ag 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
JPS5978186A (ja) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd １，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
HU198844B (en) * 1984-06-14 1989-12-28 Sandoz Ag Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
HU197201B (en) * 1985-10-01 1989-03-28 Sandoz Ag Process for producing oral pharmaceutical compositions of controlled solubility of the active components
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (ko) * 1988-10-27 1994-04-23 주식회사 유한양행 1,4-디하이드로피리딘유도체 및 그의 제조방법
DE4222770A1 (de) * 1992-07-10 1994-01-13 Bayer Ag Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine
IL163666A0 (en) 2002-02-22 2005-12-18 New River Pharmaceuticals Inc Active agent delivery systems and methods for protecting and administering active agents
WO2005023787A1 (en) * 2003-09-10 2005-03-17 Shasun Chemicals And Drugs Limited Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (zh) * 2013-11-27 2016-04-27 沈阳药科大学 一种伊拉地平合成产物后处理的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2616991A1 (de) * 1976-04-17 1977-10-27 Bayer Ag Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system
DK149855C (da) * 1977-06-20 1987-04-21 Sandoz Ag Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater

Also Published As

Publication number Publication date
IE49496B1 (en) 1985-10-16
AU5389679A (en) 1980-06-26
IT7951095A0 (it) 1979-12-14
GB2103203A (en) 1983-02-16
IT1164097B (it) 1987-04-08
GB2037766A (en) 1980-07-16
JPS5583783A (en) 1980-06-24
CH639659A5 (de) 1983-11-30
SG97585G (en) 1986-07-18
NZ192422A (en) 1982-09-14
ZA796842B (en) 1981-07-29
DE2949491A1 (de) 1980-06-26
FR2444681B1 (cs) 1982-10-29
NL7909024A (nl) 1980-06-20
NL193066C (nl) 1998-09-08
SE445219B (sv) 1986-06-09
BE880591A (fr) 1980-06-13
DE2949491C2 (cs) 1988-10-27
CY1321A (en) 1986-06-27
GB2103203B (en) 1983-06-08
GB2037766B (en) 1983-02-16
SE7910188L (sv) 1980-06-19
KE3593A (en) 1986-02-07
NL193066B (nl) 1998-05-06
FR2444681A1 (fr) 1980-07-18
NL990014I1 (nl) 1999-07-01
JPH0369910B2 (cs) 1991-11-05
HK16086A (en) 1986-03-14
MY8500130A (en) 1985-12-31
IE792445L (en) 1980-06-18

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired