AU527318B2 - Trestatin a,b, and c (amino sugars) - Google Patents

Trestatin a,b, and c (amino sugars)

Info

Publication number
AU527318B2
AU527318B2 AU44028/79A AU4402879A AU527318B2 AU 527318 B2 AU527318 B2 AU 527318B2 AU 44028/79 A AU44028/79 A AU 44028/79A AU 4402879 A AU4402879 A AU 4402879A AU 527318 B2 AU527318 B2 AU 527318B2
Authority
AU
Australia
Prior art keywords
trestatin
amino sugars
sugars
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU44028/79A
Other languages
English (en)
Other versions
AU4402879A (en
Inventor
Kiyoshi Ogawa
Yasuji Suhara
Kimihiro Watanabe
Kazuteru Yokose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of AU4402879A publication Critical patent/AU4402879A/en
Application granted granted Critical
Publication of AU527318B2 publication Critical patent/AU527318B2/en
Assigned to F. HOFFMANN-LA ROCHE AG reassignment F. HOFFMANN-LA ROCHE AG Alteration of Name(s) in Register under S187 Assignors: F. HOFFMANN-LA ROCHE & CO.
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/22Cyclohexane rings, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/99Enzyme inactivation by chemical treatment
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00Preparation of compounds containing saccharide radicals
    • C12P19/26Preparation of nitrogen-containing carbohydrates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AU44028/79A 1978-02-14 1979-02-07 Trestatin a,b, and c (amino sugars) Ceased AU527318B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB583478 1978-02-14
GB583478 1978-02-14

Publications (2)

Publication Number Publication Date
AU4402879A AU4402879A (en) 1979-08-23
AU527318B2 true AU527318B2 (en) 1983-02-24

Family

ID=9803510

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44028/79A Ceased AU527318B2 (en) 1978-02-14 1979-02-07 Trestatin a,b, and c (amino sugars)

Country Status (26)

Country Link
US (1) US4273765A (show.php)
EP (1) EP0003616B1 (show.php)
JP (1) JPS54163511A (show.php)
AR (1) AR219150A1 (show.php)
AT (1) AT367451B (show.php)
AU (1) AU527318B2 (show.php)
CA (1) CA1121290A (show.php)
DE (2) DE2962165D1 (show.php)
DK (1) DK149599C (show.php)
ES (1) ES477653A1 (show.php)
FI (1) FI63062C (show.php)
FR (1) FR2416901A1 (show.php)
GR (1) GR72817B (show.php)
HU (1) HU181442B (show.php)
IE (1) IE47916B1 (show.php)
IL (1) IL56626A0 (show.php)
LU (1) LU80906A1 (show.php)
MC (1) MC1253A1 (show.php)
NL (1) NL7901182A (show.php)
NO (1) NO153011C (show.php)
NZ (1) NZ189625A (show.php)
PH (1) PH15084A (show.php)
PT (1) PT69218A (show.php)
SE (1) SE7901276L (show.php)
YU (1) YU41437B (show.php)
ZA (1) ZA79528B (show.php)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0056194B1 (en) 1981-01-05 1984-09-12 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars, their production and use
JPS57146713A (en) * 1981-03-09 1982-09-10 Akira Endo Hypoglycemic
US4595678A (en) * 1982-03-19 1986-06-17 Takeda Chemical Industries, Ltd. N-substituted pseudo-aminosugars and pharmaceutical compositions containing same
US4678812A (en) * 1986-05-30 1987-07-07 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4762857A (en) * 1986-05-30 1988-08-09 E. I. Du Pont De Nemours And Company Trehalose as stabilizer and tableting excipient
US4885361A (en) * 1987-07-31 1989-12-05 Hoffmann-La Roche Inc. Sulfated oligosaccharides
DK0559795T3 (da) * 1990-11-30 1996-01-29 Monoclonetics Int Fremgangsmåder til diagnosticering af kroniske smerter i lænderegionen og halshvrivelsøjlen
TW381025B (en) * 1993-08-05 2000-02-01 Hoffmann La Roche Pharmaceutical composition containing a glucosidase inhibitor and a lipase inhibitor
EP1745790A3 (en) * 2000-05-24 2007-03-21 Pfizer Limited Treatment of rumen acidosis with alpha-amylase inhibitors
US7022684B2 (en) * 2000-05-24 2006-04-04 Pfizer Inc. Treatment of rumen acidosis with α-amylase inhibitors
WO2005051298A2 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US7262318B2 (en) * 2004-03-10 2007-08-28 Pfizer, Inc. Substituted heteroaryl- and phenylsulfamoyl compounds
US20050288340A1 (en) * 2004-06-29 2005-12-29 Pfizer Inc Substituted heteroaryl- and phenylsulfamoyl compounds
DE602005016009D1 (de) * 2004-11-23 2009-09-24 Warner Lambert Co 7-(2h-pyrazol-3-yl)-3,5-dihydroxy-heptansäure-derivate als hmg-co-a-reductase-inhibitoren zur behandlung von lipidemia
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
ES2393885T7 (es) 2007-06-04 2014-01-30 Synergy Pharmaceuticals Inc. Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
CN101998998A (zh) * 2008-04-11 2011-03-30 安斯泰来制药株式会社 氨基糖化合物及其生产方法
WO2009149279A2 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
WO2010093601A1 (en) 2009-02-10 2010-08-19 Metabasis Therapeutics, Inc. Novel sulfonic acid-containing thyromimetics, and methods for their use
CA2799708A1 (en) 2010-05-21 2011-11-24 Pfizer Inc. 2-phenyl benzoylamides
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
WO2012120414A2 (en) 2011-03-04 2012-09-13 Pfizer Inc. Edn3-like peptides and uses thereof
WO2013133685A1 (en) 2012-03-09 2013-09-12 Biotropics Malaysia Berhad Extract formulations of rhodamnia cinerea and uses thereof
WO2014151206A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのn−ピペリジン−3−イルベンズアミド誘導体
EP3004138B1 (en) 2013-06-05 2024-03-13 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same
MX389591B (es) 2014-08-29 2025-03-20 Tes Pharma S R L INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
US20180134667A1 (en) 2016-10-14 2018-05-17 TES Pharma S.r.I. Inhibitors of alpha-amino-beta-carboxymuconic acid semialdehyde decarboxylase
AR117122A1 (es) 2018-11-20 2021-07-14 Tes Pharma S R L INHIBIDORES DE LA ÁCIDO a-AMINO-b-CARBOXIMUCÓNICO SEMIALDEHÍDO DESCARBOXILASA
BR112021013807A2 (pt) 2019-01-18 2021-11-30 Astrazeneca Ab Inibidores de pcsk9 e seus métodos de uso

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2064092C2 (de) * 1970-12-28 1983-06-01 Bayer Ag, 5090 Leverkusen Inhibitoren für Glykosidhydrolasen aus Actinomyceten
DE2347782C3 (de) * 1973-09-22 1979-10-11 Bayer Ag, 5090 Leverkusen Aminozuckerderivate, Verfahren zu ihrer Herstellung sowie diese Verbindungen enthaltende Arzneimittel
US4062950A (en) * 1973-09-22 1977-12-13 Bayer Aktiengesellschaft Amino sugar derivatives
US4065557A (en) * 1974-03-21 1977-12-27 Bayer Aktiengesellschaft Amino sugars and their use in improving the meat:fat ratio in animals
USRE29903E (en) 1975-03-19 1979-02-06 American Cyanamid Company Antibacterial antibiotics AM31α, AM31β and AM31γ
DE2614393C3 (de) * 1976-04-02 1980-04-03 Bayer Ag, 5090 Leverkusen Aminozucker-Derivate und diese Verbindungen enthaltende Arzneimittel

Also Published As

Publication number Publication date
AT367451B (de) 1982-07-12
JPS54163511A (en) 1979-12-26
AU4402879A (en) 1979-08-23
NO153011C (no) 1986-01-02
EP0003616B1 (de) 1982-02-24
DK61179A (da) 1979-08-15
DE2962165D1 (en) 1982-03-25
PH15084A (en) 1982-07-02
HU181442B (en) 1983-07-28
ZA79528B (en) 1980-02-27
IL56626A0 (en) 1979-05-31
FI63062C (fi) 1983-04-11
FI63062B (fi) 1982-12-31
EP0003616A3 (en) 1979-09-05
PT69218A (en) 1979-03-01
NO153011B (no) 1985-09-23
EP0003616A2 (de) 1979-08-22
IE790274L (en) 1979-08-14
IE47916B1 (en) 1984-07-25
GR72817B (show.php) 1983-12-06
ATA108879A (de) 1981-11-15
FR2416901A1 (fr) 1979-09-07
MC1253A1 (fr) 1980-01-14
DK149599B (da) 1986-08-04
FI790486A7 (fi) 1979-08-15
NZ189625A (en) 1981-05-01
US4273765A (en) 1981-06-16
NO790469L (no) 1979-08-15
DE2905649A1 (de) 1979-08-16
LU80906A1 (de) 1980-09-24
NL7901182A (nl) 1979-08-16
AR219150A1 (es) 1980-07-31
YU41437B (en) 1987-06-30
DK149599C (da) 1987-06-01
CA1121290A (en) 1982-04-06
YU34879A (en) 1983-01-21
FR2416901B1 (show.php) 1980-10-24
SE7901276L (sv) 1979-08-15
ES477653A1 (es) 1980-03-01
JPS643877B2 (show.php) 1989-01-23

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