AU520625B2 - 1-acyl-2-hydroxy-1, 3-diaminopropanes - Google Patents

1-acyl-2-hydroxy-1, 3-diaminopropanes

Info

Publication number
AU520625B2
AU520625B2 AU35941/78A AU3594178A AU520625B2 AU 520625 B2 AU520625 B2 AU 520625B2 AU 35941/78 A AU35941/78 A AU 35941/78A AU 3594178 A AU3594178 A AU 3594178A AU 520625 B2 AU520625 B2 AU 520625B2
Authority
AU
Australia
Prior art keywords
hydroxy
diaminopropane
methyl
phenyl
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU35941/78A
Other languages
English (en)
Other versions
AU3594178A (en
Inventor
H. ET AL Liepmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AbbVie Pharmaceuticals GmbH
Original Assignee
Kali Chemie Pharma GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2720915A external-priority patent/DE2720915C2/de
Priority claimed from DE19772720968 external-priority patent/DE2720968C2/de
Application filed by Kali Chemie Pharma GmbH filed Critical Kali Chemie Pharma GmbH
Publication of AU3594178A publication Critical patent/AU3594178A/en
Application granted granted Critical
Publication of AU520625B2 publication Critical patent/AU520625B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/36—Compounds containing oxirane rings with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU35941/78A 1977-05-10 1978-05-09 1-acyl-2-hydroxy-1, 3-diaminopropanes Expired AU520625B2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE2720915A DE2720915C2 (de) 1977-05-10 1977-05-10 N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel mit diesen Verbindungen als Wirkstoff
DEDE2720915 1977-05-10
DEDE2720968 1977-05-10
DE19772720968 DE2720968C2 (de) 1977-05-10 1977-05-10 N↓1↓-Acyl-2-hydroxy-1,3-diaminopropane und Arzneimittel

Publications (2)

Publication Number Publication Date
AU3594178A AU3594178A (en) 1979-11-15
AU520625B2 true AU520625B2 (en) 1982-02-11

Family

ID=25771998

Family Applications (1)

Application Number Title Priority Date Filing Date
AU35941/78A Expired AU520625B2 (en) 1977-05-10 1978-05-09 1-acyl-2-hydroxy-1, 3-diaminopropanes

Country Status (18)

Country Link
US (2) US4191770A (enExample)
JP (1) JPS53141224A (enExample)
AT (1) AT357144B (enExample)
AU (1) AU520625B2 (enExample)
CH (1) CH636845A5 (enExample)
DD (1) DD135195A5 (enExample)
DK (1) DK201878A (enExample)
ES (1) ES469020A1 (enExample)
FR (1) FR2390422A1 (enExample)
GB (1) GB1585758A (enExample)
IE (1) IE46778B1 (enExample)
IL (1) IL54677A (enExample)
IT (1) IT1098213B (enExample)
NL (1) NL7805038A (enExample)
NO (1) NO147749C (enExample)
NZ (1) NZ187221A (enExample)
PH (1) PH14558A (enExample)
SU (1) SU906365A3 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2459235A1 (fr) * 1979-06-14 1981-01-09 Sanofi Sa Nouveaux derives de sulfonyl-aniline, leur procede de preparation et leur application therapeutique
JPS58177953A (ja) * 1982-04-13 1983-10-18 Eisai Co Ltd ポリプレニルカルボン酸アミドおよびその製造方法
US4596813A (en) * 1982-11-04 1986-06-24 Chevron Research Company Pyridylcarbonyl and thiocarbonyl derivatives useful as fungicides
ATE179164T1 (de) * 1993-01-15 1999-05-15 Agouron Pharma Hiv-proteaseinhibitoren
US5824821A (en) * 1997-02-07 1998-10-20 Nycomed Imaging As Process for the preparation of iodinated contrast agents and intermediates therefor
NZ504372A (en) 1997-11-07 2002-12-20 Upjohn Co Process to produce N-[3-fluoro-4(4-morpholinyl)phenyl]-2-oxo-5-oxazolidinones

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1805355A (en) * 1929-01-02 1931-05-12 Ig Farbenindustrie Ag Basic compounds and process of preparing them
US2658076A (en) * 1951-06-12 1953-11-03 Searle & Co N-dialkylaminoalkyl derivatives of alpha, beta-diarylalkanoamides and their salts
BE794424A (fr) * 1972-01-24 1973-07-23 Science Union & Cie Nouveaux dibenzocycloheptenes, leur procede d'obtention et leur application comme medicament
DE2265370C2 (de) * 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 6-Phenyl-1,2,3,4-tetrahydro-1,5-benzodiazocinderivate
GB1374366A (en) * 1972-07-21 1974-11-20 Science Union & Cie Propanol derivatives and a process for their preparation
GB1436593A (en) * 1973-03-15 1976-05-19 Science Union & Cie N-substituted acetamides processes for their preparation and pharmaceutical compositions containing them apparatus for processing photograp
DE2314993A1 (de) * 1973-03-26 1974-10-03 Kali Chemie Pharma Gmbh Neue benzodiazepinderivate und verfahren zu deren herstellung
US4141987A (en) * 1974-06-05 1979-02-27 Imperial Chemical Industries Limited 1-Aryloxy-3-thenamidoalkylamino-2-propanol derivatives
DE2448259A1 (de) * 1974-10-10 1976-04-22 Kali Chemie Pharma Gmbh Verfahren zur herstellung von 2-halogenmethyl-1,4-benzodiazepinen
US4144343A (en) * 1978-01-04 1979-03-13 Merck & Co., Inc. Heterocycle substituted (3-loweralkylamino-2-R1 O-propoxy)pyridines

Also Published As

Publication number Publication date
IL54677A0 (en) 1978-07-31
IT1098213B (it) 1985-09-07
ES469020A1 (es) 1979-09-01
IL54677A (en) 1981-02-27
AT357144B (de) 1980-06-25
NO147749B (no) 1983-02-28
US4191770A (en) 1980-03-04
JPS6252740B2 (enExample) 1987-11-06
IE780921L (en) 1978-11-10
FR2390422B1 (enExample) 1980-07-18
IT7823159A0 (it) 1978-05-09
DD135195A5 (de) 1979-04-18
NZ187221A (en) 1980-12-19
NO781631L (no) 1978-11-13
IE46778B1 (en) 1983-09-21
SU906365A3 (ru) 1982-02-15
JPS53141224A (en) 1978-12-08
CH636845A5 (de) 1983-06-30
DK201878A (da) 1979-02-14
GB1585758A (en) 1981-03-11
PH14558A (en) 1981-09-24
US4402981A (en) 1983-09-06
NO147749C (no) 1983-06-08
NL7805038A (nl) 1978-11-14
AU3594178A (en) 1979-11-15
ATA335178A (de) 1979-11-15
FR2390422A1 (fr) 1978-12-08

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