|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
|
US6852690B1
(en)
|
1995-08-22 |
2005-02-08 |
Amylin Pharmaceuticals, Inc. |
Method and composition for enhanced parenteral nutrition
|
|
UA65549C2
(uk)
|
1996-11-05 |
2004-04-15 |
Елі Ліллі Енд Компані |
Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
|
|
US6380357B2
(en)
|
1997-12-16 |
2002-04-30 |
Eli Lilly And Company |
Glucagon-like peptide-1 crystals
|
|
US6998387B1
(en)
|
1998-03-19 |
2006-02-14 |
Amylin Pharmaceuticals, Inc. |
Human appetite control by glucagon-like peptide receptor binding compounds
|
|
US7223727B2
(en)
|
1998-04-09 |
2007-05-29 |
Serono Genetics Institute S.A. |
GSSP4 polynucleotides and polypeptides and uses thereof
|
|
US6720407B1
(en)
*
|
1998-08-28 |
2004-04-13 |
Eli Lilly And Company |
Method for administering insulinotropic peptides
|
|
US6927214B1
(en)
|
1999-01-15 |
2005-08-09 |
Novo Nordisk A/S |
Non-peptide GLP-1 agonists
|
|
US6514500B1
(en)
*
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
|
EP1808438B1
(en)
|
1999-06-29 |
2014-10-01 |
MannKind Corporation |
Purification and stabilization of peptide and proteins in pharmaceutical agents
|
|
US9006175B2
(en)
|
1999-06-29 |
2015-04-14 |
Mannkind Corporation |
Potentiation of glucose elimination
|
|
EP1229927B1
(en)
*
|
1999-11-03 |
2007-12-19 |
Novo Nordisk A/S |
Use of a growth hormone or a growth hormone secretagogue for appetite-suppression or induction of satiety
|
|
AU2001261024A1
(en)
|
2000-04-12 |
2001-10-30 |
Delta Biotechnology Limited |
Albumin fusion proteins
|
|
WO2001087341A1
(en)
*
|
2000-05-16 |
2001-11-22 |
Sanwa Kagaku Kenkyusho Co.,Ltd. |
Agents for preventing or ameliorating insulin resistance and/or obesity
|
|
ATE405323T1
(de)
*
|
2001-02-09 |
2008-09-15 |
Serono Genetics Inst Sa |
Gssp4-polynukleotide und -polypeptide sowie deren verwendung
|
|
ES2320979T3
(es)
|
2001-09-24 |
2009-06-01 |
Imperial Innovations Limited |
Pyy-36 para la reduccion o prevencion de la obesidad.
|
|
EP2277910A1
(en)
|
2001-12-21 |
2011-01-26 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
EP1463752A4
(en)
|
2001-12-21 |
2005-07-13 |
Human Genome Sciences Inc |
ALBUMIN FUSION PROTEINS
|
|
MXPA04008068A
(es)
|
2002-02-20 |
2004-11-26 |
Lilly Co Eli |
Metodo para administrar moleculas de glp-1.
|
|
ES2425392T3
(es)
|
2002-03-20 |
2013-10-15 |
Mannkind Corporation |
Cartucho para un aparato de inhalación
|
|
US7407955B2
(en)
|
2002-08-21 |
2008-08-05 |
Boehringer Ingelheim Pharma Gmbh & Co., Kg |
8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
|
|
EP1594530A4
(en)
|
2003-01-22 |
2006-10-11 |
Human Genome Sciences Inc |
HYBRID PROTEINS OF ALBUMIN
|
|
DE602004031455D1
(de)
|
2003-12-09 |
2011-03-31 |
Novo Nordisk As |
Regulierung der nahrungspräferenz mit glp-1-agonisten
|
|
US20060286129A1
(en)
|
2003-12-19 |
2006-12-21 |
Emisphere Technologies, Inc. |
Oral GLP-1 formulations
|
|
EP1729795B1
(en)
|
2004-02-09 |
2016-02-03 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
|
PT2100904E
(pt)
|
2004-04-23 |
2010-09-24 |
Conjuchem Biotechnologies Inc |
Fase sólida para utilização num método para a purificação de conjugados de albumina
|
|
JP2008501765A
(ja)
|
2004-06-11 |
2008-01-24 |
ノボ ノルディスク アクティーゼルスカブ |
Glp−1アゴニストを用いた薬剤誘発性肥満の中和
|
|
DK1786784T3
(da)
|
2004-08-20 |
2011-02-14 |
Mannkind Corp |
Katalyse af diketopiperazinsyntese
|
|
BR122019022692B1
(pt)
|
2004-08-23 |
2023-01-10 |
Mannkind Corporation |
Composição terapêutica em pó seco contendo dicetopiperazina, pelo menos um tipo de cátion e um agente biologicamente ativo
|
|
DE102004054054A1
(de)
|
2004-11-05 |
2006-05-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
|
|
MX2008001468A
(es)
|
2005-06-30 |
2008-04-07 |
Sod Conseils Rech Applic |
Composiciones farmaceuticas del peptido similar al glucagon-1.
|
|
WO2007033372A2
(en)
|
2005-09-14 |
2007-03-22 |
Mannkind Corporation |
Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents
|
|
ES2336575T3
(es)
|
2005-09-22 |
2010-04-14 |
Biocompatibles Uk Limited |
Polipeptidos de fusion glp-1 (peptido-1 similar al glucagon) con resistencia aumentada a la peptidasa.
|
|
US8039432B2
(en)
|
2005-11-09 |
2011-10-18 |
Conjuchem, Llc |
Method of treatment of diabetes and/or obesity with reduced nausea side effect
|
|
WO2007075534A2
(en)
|
2005-12-16 |
2007-07-05 |
Nektar Therapeutics Al, Corporation |
Polymer conjugates of glp-1
|
|
DK1986679T3
(da)
|
2006-02-22 |
2017-11-20 |
Mannkind Corp |
Fremgangsmåde til forbedring af mikropartiklers farmaceutiske egenskaber omfattende diketopiperazin og et aktivt indholdsstof
|
|
EP1852108A1
(en)
|
2006-05-04 |
2007-11-07 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
DPP IV inhibitor formulations
|
|
PE20110235A1
(es)
|
2006-05-04 |
2011-04-14 |
Boehringer Ingelheim Int |
Combinaciones farmaceuticas que comprenden linagliptina y metmorfina
|
|
SG174054A1
(en)
|
2006-05-04 |
2011-09-29 |
Boehringer Ingelheim Int |
Polymorphs
|
|
ATE444741T1
(de)
|
2006-05-10 |
2009-10-15 |
Biocompatibles Uk Ltd |
Glp-1 peptide enthaltende kugelförmige mikrokapseln, deren produktion und deren verwendung
|
|
JP5102833B2
(ja)
*
|
2006-07-24 |
2012-12-19 |
バイオレクシス ファーマシューティカル コーポレーション |
エキセンディン融合タンパク質
|
|
TWI428346B
(zh)
|
2006-12-13 |
2014-03-01 |
Imp Innovations Ltd |
新穎化合物及其等對進食行為影響
|
|
EP2190873B1
(en)
|
2007-09-05 |
2015-07-22 |
Novo Nordisk A/S |
Truncated glp-1 derivatives and their therapeutical use
|
|
JP5476304B2
(ja)
|
2007-09-05 |
2014-04-23 |
ノボ・ノルデイスク・エー/エス |
グルカゴン様ペプチド−1誘導体及びそれらの医薬用途
|
|
KR20100090692A
(ko)
*
|
2007-10-24 |
2010-08-16 |
맨카인드 코포레이션 |
활성제의 전달
|
|
US8785396B2
(en)
|
2007-10-24 |
2014-07-22 |
Mannkind Corporation |
Method and composition for treating migraines
|
|
HUE025485T2
(en)
*
|
2007-10-24 |
2016-02-29 |
Mannkind Corp |
Respiratory dry powder formulation containing GLP-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration
|
|
PE20140960A1
(es)
|
2008-04-03 |
2014-08-15 |
Boehringer Ingelheim Int |
Formulaciones que comprenden un inhibidor de dpp4
|
|
CA3153292A1
(en)
|
2008-06-13 |
2009-12-17 |
Mannkind Corporation |
A dry powder inhaler and system for drug delivery
|
|
US8485180B2
(en)
|
2008-06-13 |
2013-07-16 |
Mannkind Corporation |
Dry powder drug delivery system
|
|
CN102065942B
(zh)
|
2008-06-20 |
2013-12-11 |
曼金德公司 |
用于对吸入工作进行实时描绘的交互式设备和方法
|
|
BRPI0916997A2
(pt)
|
2008-08-06 |
2020-12-15 |
Boehringer Ingelheim International Gmbh |
Inibidor de dpp-4 e seu uso
|
|
TWI532497B
(zh)
|
2008-08-11 |
2016-05-11 |
曼凱公司 |
超快起作用胰島素之用途
|
|
US20200155558A1
(en)
|
2018-11-20 |
2020-05-21 |
Boehringer Ingelheim International Gmbh |
Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
|
|
US8314106B2
(en)
|
2008-12-29 |
2012-11-20 |
Mannkind Corporation |
Substituted diketopiperazine analogs for use as drug delivery agents
|
|
EP2216042A1
(en)
|
2009-02-09 |
2010-08-11 |
Ipsen Pharma S.A.S. |
GLP-1 analogues pharmaceutical compositions
|
|
PL2405963T3
(pl)
|
2009-03-11 |
2014-04-30 |
Mannkind Corp |
Urządzenie, układ i sposób pomiaru oporu inhalatora
|
|
KR20180036807A
(ko)
|
2009-06-12 |
2018-04-09 |
맨카인드 코포레이션 |
한정된 비표면적을 갖는 디케토피페라진 마이크로입자
|
|
US20120148586A1
(en)
|
2009-08-27 |
2012-06-14 |
Joyce Ching Tsu Chou |
Glucagon-like protein-1 receptor (glp-1r) agonists for treating autoimmune disorders
|
|
CA2778698A1
(en)
|
2009-11-03 |
2011-05-12 |
Mannkind Corporation |
An apparatus and method for simulating inhalation efforts
|
|
EP3646859A1
(en)
|
2009-11-27 |
2020-05-06 |
Boehringer Ingelheim International GmbH |
Treatment of genotyped diabetic patients with dpp-iv inhibitors such as linagliptin
|
|
NZ602921A
(en)
|
2010-05-05 |
2016-01-29 |
Boehringer Ingelheim Int |
Combination therapy comprising the administration of a glp-1 receptor agonist and a ddp-4 inhibitor
|
|
RU2571331C1
(ru)
|
2010-06-21 |
2015-12-20 |
Маннкайнд Корпорейшн |
Системы и способы доставки сухих порошковых лекарств
|
|
EP2588490B1
(en)
|
2010-07-02 |
2017-02-22 |
Angiochem Inc. |
Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof
|
|
AR083878A1
(es)
|
2010-11-15 |
2013-03-27 |
Boehringer Ingelheim Int |
Terapia antidiabetica vasoprotectora y cardioprotectora, linagliptina, metodo de tratamiento
|
|
RS60321B1
(sr)
|
2010-12-16 |
2020-07-31 |
Novo Nordisk As |
Čvrste kompozicije koje sadrže glp-1 agonist i so n-(8-(2- hidroksibenzoil)amino)kaprilne kiseline
|
|
KR101940832B1
(ko)
|
2011-04-01 |
2019-01-21 |
맨카인드 코포레이션 |
의약 카트리지용 블리스터 패키지
|
|
DK2696687T3
(en)
|
2011-04-12 |
2017-02-06 |
Novo Nordisk As |
Double-acylated GLP-1 derivatives
|
|
WO2012174472A1
(en)
|
2011-06-17 |
2012-12-20 |
Mannkind Corporation |
High capacity diketopiperazine microparticles
|
|
EP2776053A1
(en)
|
2011-10-24 |
2014-09-17 |
MannKind Corporation |
Methods and compositions for treating pain
|
|
US20130172244A1
(en)
*
|
2011-12-29 |
2013-07-04 |
Thomas Klein |
Subcutaneous therapeutic use of dpp-4 inhibitor
|
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
|
HUE042757T2
(hu)
|
2012-03-22 |
2019-07-29 |
Novo Nordisk As |
Szállító szert tartalmazó készítmények és elõállításuk
|
|
PL2827885T3
(pl)
|
2012-03-22 |
2019-01-31 |
Novo Nordisk A/S |
Kompozycje peptydów GLP-1 i ich otrzymywanie
|
|
EP4151218A1
(en)
|
2012-05-14 |
2023-03-22 |
Boehringer Ingelheim International GmbH |
Linagliptin, a xanthine derivative as dpp-4 inhibitor, for use in the treatment of sirs and/or sepsis
|
|
US20130303462A1
(en)
|
2012-05-14 |
2013-11-14 |
Boehringer Ingelheim International Gmbh |
Use of a dpp-4 inhibitor in podocytes related disorders and/or nephrotic syndrome
|
|
WO2013174767A1
(en)
|
2012-05-24 |
2013-11-28 |
Boehringer Ingelheim International Gmbh |
A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference
|
|
WO2013189988A1
(en)
|
2012-06-20 |
2013-12-27 |
Novo Nordisk A/S |
Tablet formulation comprising a peptide and a delivery agent
|
|
CN104619369B
(zh)
|
2012-07-12 |
2018-01-30 |
曼金德公司 |
干粉药物输送系统和方法
|
|
EP2911690A1
(en)
|
2012-10-26 |
2015-09-02 |
MannKind Corporation |
Inhalable influenza vaccine compositions and methods
|
|
AU2014228415B2
(en)
|
2013-03-15 |
2018-08-09 |
Mannkind Corporation |
Microcrystalline diketopiperazine compositions and methods
|
|
KR20210086717A
(ko)
|
2013-05-02 |
2021-07-08 |
노보 노르디스크 에이/에스 |
Glp-1 화합물의 경구 투여
|
|
UA118558C2
(uk)
|
2013-05-28 |
2019-02-11 |
Такеда Фармасьютікал Компані Лімітед |
Пептидна сполука
|
|
CA2918369C
(en)
|
2013-07-18 |
2021-06-29 |
Mannkind Corporation |
Heat-stable dry powder pharmaceutical compositions and methods
|
|
WO2015021064A1
(en)
|
2013-08-05 |
2015-02-12 |
Mannkind Corporation |
Insufflation apparatus and methods
|
|
EP3110449B1
(en)
|
2014-02-28 |
2023-06-28 |
Boehringer Ingelheim International GmbH |
Medical use of a dpp-4 inhibitor
|
|
US10307464B2
(en)
|
2014-03-28 |
2019-06-04 |
Mannkind Corporation |
Use of ultrarapid acting insulin
|
|
US10561806B2
(en)
|
2014-10-02 |
2020-02-18 |
Mannkind Corporation |
Mouthpiece cover for an inhaler
|
|
JP6995042B2
(ja)
|
2016-05-24 |
2022-02-04 |
武田薬品工業株式会社 |
ペプチド化合物
|
|
EP3468562A1
(en)
|
2016-06-10 |
2019-04-17 |
Boehringer Ingelheim International GmbH |
Combinations of linagliptin and metformin
|
|
CN111683676B
(zh)
|
2018-02-02 |
2024-06-18 |
诺和诺德股份有限公司 |
包含glp-1激动剂、n-(8-(2-羟基苯甲酰基)氨基)辛酸的盐和润滑剂的固体组合物
|
|
CN113181346A
(zh)
*
|
2018-03-09 |
2021-07-30 |
上海仁会生物制药股份有限公司 |
用于治疗肥胖和体重管理的glp-1组合物
|