AU474687B2 - Pregnane anaesthetics - Google Patents
Pregnane anaestheticsInfo
- Publication number
- AU474687B2 AU474687B2 AU55616/73A AU5561673A AU474687B2 AU 474687 B2 AU474687 B2 AU 474687B2 AU 55616/73 A AU55616/73 A AU 55616/73A AU 5561673 A AU5561673 A AU 5561673A AU 474687 B2 AU474687 B2 AU 474687B2
- Authority
- AU
- Australia
- Prior art keywords
- pregnane
- anaesthetics
- pregnane anaesthetics
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JWMFYGXQPXQEEM-NUNROCCHSA-N 5β-pregnane Chemical compound C([C@H]1CC2)CCC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H](CC)[C@@]2(C)CC1 JWMFYGXQPXQEEM-NUNROCCHSA-N 0.000 title 1
- 229940124326 anaesthetic agent Drugs 0.000 title 1
- 230000003444 anaesthetic effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2248972A GB1436324A (en) | 1972-05-12 | 1972-05-12 | Anaesthetic 3alpha-hydroxy pregnanes |
| GBGB22489/72 | 1972-05-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU5561673A AU5561673A (en) | 1974-11-14 |
| AU474687B2 true AU474687B2 (en) | 1976-07-29 |
Family
ID=10180241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU55616/73A Expired AU474687B2 (en) | 1972-05-12 | 1973-05-11 | Pregnane anaesthetics |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US3998829A (en, 2012) |
| JP (1) | JPS4948652A (en, 2012) |
| AU (1) | AU474687B2 (en, 2012) |
| BE (1) | BE799433A (en, 2012) |
| CA (1) | CA1014947A (en, 2012) |
| DE (1) | DE2323950A1 (en, 2012) |
| DK (1) | DK135775B (en, 2012) |
| FR (1) | FR2184711B1 (en, 2012) |
| GB (1) | GB1436324A (en, 2012) |
| IE (1) | IE38863B1 (en, 2012) |
| LU (1) | LU67585A1 (en, 2012) |
| NL (1) | NL7306606A (en, 2012) |
| ZA (1) | ZA733218B (en, 2012) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4613463A (en) * | 1984-11-01 | 1986-09-23 | The Upjohn Company | Process and intermediates for the preparation of 17 alphahydroxyprogesterones and corticoids from an enol steroid |
| USRE35053E (en) * | 1985-09-12 | 1995-10-10 | The Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
| US5099019A (en) * | 1985-09-12 | 1992-03-24 | Upjohn Company | Amines useful in producing pharmaceutically active CNS compounds |
| US5380840A (en) * | 1985-09-12 | 1995-01-10 | The Upjohn Company | Triazinylpiperazinyl steroids |
| US5232917A (en) * | 1987-08-25 | 1993-08-03 | University Of Southern California | Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series |
| JPH072555Y2 (ja) * | 1991-06-03 | 1995-01-25 | 日野自動車工業株式会社 | 車輛の前後方向兼用ウインチ |
| US6780853B1 (en) | 1995-06-06 | 2004-08-24 | Euro-Celtique S.A. | Neuroactive steroids of the androstane and pregnane series |
| BR9608592A (pt) * | 1995-06-06 | 1999-06-29 | Cocensys Inc | Esteróides neuroativos da série do androstano e do pregnano |
| US6143737A (en) * | 1995-06-23 | 2000-11-07 | Georgetown University | Progesterone analogs to reverse multidrug resistance |
| HUP0201818A3 (en) * | 1999-04-29 | 2004-04-28 | Euro Celtique Sa | 3alpha-hydroxy-3beta-methoxymethyl-21-heterocycle substituted steroids with anesthetic activity and pharmaceutical compositions containing the same |
| US20050101581A1 (en) * | 2002-08-28 | 2005-05-12 | Reading Christopher L. | Therapeutic treatment methods 2 |
| EP3572417A3 (en) | 2011-10-14 | 2020-03-25 | Sage Therapeutics, Inc. | 3,3 disubstituted 19-nor pregnane compounds, compositions, and uses thereof |
| US9365611B2 (en) | 2013-04-17 | 2016-06-14 | Sage Therapeutics, Inc. | 19-NOR neuroactive steroids and methods of use thereof |
| US9725481B2 (en) | 2013-04-17 | 2017-08-08 | Sage Therapeutics, Inc. | 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof |
| HRP20190232T1 (hr) | 2013-04-17 | 2019-03-22 | Sage Therapeutics, Inc. | 19-nor c3,3-disupstituirani c21-n-pirazolil steroidi i postupci za njihovu upotrebu |
| WO2014169836A1 (en) | 2013-04-17 | 2014-10-23 | Sage Therapeutics, Inc. | 19-nor neuroactive steroids and methods of use thereof |
| HRP20210610T1 (hr) | 2013-07-19 | 2021-05-28 | Sage Therapeutics, Inc. | Neuroaktivni steroidi, pripravci i njihove uporabe |
| EP3831387A1 (en) | 2013-08-23 | 2021-06-09 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US10246482B2 (en) | 2014-06-18 | 2019-04-02 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| US20170233433A1 (en) | 2014-10-16 | 2017-08-17 | Sage Therapeutics, Inc. | Compositions and methods for treating cns disorders |
| PH12017500711B1 (en) | 2014-10-16 | 2022-12-09 | Sage Therapeutics Inc | Compositions and methods for treating cns disorders |
| EP3719029A1 (en) | 2014-11-27 | 2020-10-07 | Sage Therapeutics, Inc. | Compositions for inducing sedation |
| PT3250210T (pt) | 2015-01-26 | 2021-03-26 | Sage Therapeutics Inc | Composições e métodos para o tratamento de distúrbios do snc |
| WO2016134301A2 (en) | 2015-02-20 | 2016-08-25 | Sage Therapeutics, Inc. | Neuroactive steroids, compositions, and uses thereof |
| AU2017296295B2 (en) | 2016-07-11 | 2022-02-24 | Sage Therapeutics, Inc. | C7, C12, and C16 substituted neuroactive steroids and their methods of use |
| EP3481845B1 (en) | 2016-07-11 | 2023-09-13 | Sage Therapeutics, Inc. | C17, c20, and c21 substituted neuroactive steroids and their methods of use |
| EP3976628A1 (en) | 2019-05-31 | 2022-04-06 | Sage Therapeutics, Inc. | Neuroactive steroids and compositions thereof |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1107662B (de) * | 1959-07-04 | 1961-05-31 | Merck Ag E | Verfahren zur Herstellung von Mannichbasen von Steroiden bzw. von deren Saeureadditionssalzen |
| US3042691A (en) * | 1960-05-11 | 1962-07-03 | Pfizer & Co C | 5alpha,21-dibromo-6beta-fluoro-21-methyl-pregnanes and process for making same |
| FR1764M (fr) * | 1962-02-20 | 1963-04-08 | Roussel Uclaf | Nouveau médicament notamment pour le traitement des spasmes d'origine coronarienne ou viscérale. |
| US3201425A (en) * | 1963-12-10 | 1965-08-17 | American Cyanamid Co | 20-alkoxy-delta20-21-carboxaldehydes of the pregnane series and method of preparing the same |
| GB1089945A (en) * | 1965-09-23 | 1967-11-08 | British Drug Houses Ltd | Steroidal-6-spirocyclopropyl-4-en-3-ones |
| GB1317184A (en) * | 1969-06-20 | 1973-05-16 | Glaxo Lab Ltd | Steroid-containing pharmaceutical preparations |
| DE1941226A1 (de) * | 1969-08-13 | 1971-02-18 | Degussa | Basisch substituierte Ketosteroide |
| US3661940A (en) * | 1970-04-13 | 1972-05-09 | Sandoz Ag | Derivatives of 21-methyl-19-norpregnanes |
| GB1377609A (en) * | 1970-12-17 | 1974-12-18 | Glaxo Lab Ltd | 3alpha-hydroxy-5alpha-pregnane compounds |
| GB1416427A (en) * | 1972-01-12 | 1975-12-03 | Akzo Nv | Alkylated pregnanes and process for obtaining same |
-
1972
- 1972-05-12 GB GB2248972A patent/GB1436324A/en not_active Expired
-
1973
- 1973-05-08 US US05/358,381 patent/US3998829A/en not_active Expired - Lifetime
- 1973-05-11 ZA ZA733218A patent/ZA733218B/xx unknown
- 1973-05-11 NL NL7306606A patent/NL7306606A/xx not_active Application Discontinuation
- 1973-05-11 LU LU67585A patent/LU67585A1/xx unknown
- 1973-05-11 IE IE00753/73A patent/IE38863B1/xx unknown
- 1973-05-11 DE DE2323950A patent/DE2323950A1/de not_active Ceased
- 1973-05-11 DK DK260473AA patent/DK135775B/da unknown
- 1973-05-11 JP JP48052424A patent/JPS4948652A/ja active Pending
- 1973-05-11 AU AU55616/73A patent/AU474687B2/en not_active Expired
- 1973-05-11 CA CA171,026A patent/CA1014947A/en not_active Expired
- 1973-05-11 BE BE131031A patent/BE799433A/xx unknown
- 1973-05-11 FR FR7317079A patent/FR2184711B1/fr not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ZA733218B (en) | 1974-05-29 |
| GB1436324A (en) | 1976-05-19 |
| NL7306606A (en, 2012) | 1973-11-14 |
| FR2184711A1 (en, 2012) | 1973-12-28 |
| LU67585A1 (en, 2012) | 1973-07-24 |
| CA1014947A (en) | 1977-08-02 |
| DK135775B (da) | 1977-06-20 |
| DK135775C (en, 2012) | 1977-11-21 |
| IE38863B1 (en) | 1978-06-21 |
| US3998829A (en) | 1976-12-21 |
| AU5561673A (en) | 1974-11-14 |
| JPS4948652A (en, 2012) | 1974-05-11 |
| BE799433A (fr) | 1973-11-12 |
| DE2323950A1 (de) | 1973-12-13 |
| FR2184711B1 (en, 2012) | 1977-01-07 |
| IE38863L (en) | 1973-11-12 |
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