AU4450700A - Insulin crystals for pulmonary administration - Google Patents

Insulin crystals for pulmonary administration

Info

Publication number
AU4450700A
AU4450700A AU44507/00A AU4450700A AU4450700A AU 4450700 A AU4450700 A AU 4450700A AU 44507/00 A AU44507/00 A AU 44507/00A AU 4450700 A AU4450700 A AU 4450700A AU 4450700 A AU4450700 A AU 4450700A
Authority
AU
Australia
Prior art keywords
pulmonary administration
insulin crystals
insulin
crystals
pulmonary
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44507/00A
Other languages
English (en)
Inventor
Mark Laurence Brader
Benjamin Lee Hughes
Shun Li
Kingman Ng
Muppalla Sukumar
Ronald Keith Wolff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU4450700A publication Critical patent/AU4450700A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
AU44507/00A 1999-04-27 2000-04-13 Insulin crystals for pulmonary administration Abandoned AU4450700A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13117099P 1999-04-27 1999-04-27
US60131170 1999-04-27
PCT/US2000/008723 WO2000064940A1 (en) 1999-04-27 2000-04-13 Insulin crystals for pulmonary administration

Publications (1)

Publication Number Publication Date
AU4450700A true AU4450700A (en) 2000-11-10

Family

ID=22448221

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44507/00A Abandoned AU4450700A (en) 1999-04-27 2000-04-13 Insulin crystals for pulmonary administration

Country Status (5)

Country Link
EP (1) EP1173482A1 (de)
JP (1) JP2002543092A (de)
AU (1) AU4450700A (de)
CA (1) CA2370302A1 (de)
WO (1) WO2000064940A1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4357842B2 (ja) 2001-05-24 2009-11-04 アレックザ ファーマシューティカルズ， インコーポレイテッド 所定の吸入ルートによるアルプラゾラム、エスタゾラム、ミダゾラムまたはトリアゾラムの送出
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
US6759029B2 (en) 2001-05-24 2004-07-06 Alexza Molecular Delivery Corporation Delivery of rizatriptan and zolmitriptan through an inhalation route
US7078016B2 (en) 2001-11-21 2006-07-18 Alexza Pharmaceuticals, Inc. Delivery of caffeine through an inhalation route
US6805853B2 (en) 2001-11-09 2004-10-19 Alexza Molecular Delivery Corporation Delivery of diazepam through an inhalation route
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
EP1270012A1 (de) * 2001-06-21 2003-01-02 Pfizer Products Inc. Verwendung pulmonär verabreichten Insulins zur Behandlung von Diabetes
US7317000B2 (en) 2001-12-02 2008-01-08 Novo Nordisk A/S Glucose-dependent insulins
EP1453860A2 (de) * 2001-12-02 2004-09-08 Novo Nordisk A/S Neue glukoseabhängige insuline
CA2518216C (en) * 2003-03-06 2017-05-09 Emisphere Technologies, Inc. Oral insulin therapies and protocol
JP2006519881A (ja) * 2003-03-06 2006-08-31 エミスフィアー テクノロジーズ インコーポレイテッド 経口インスリン治療及びプロトコール
ATE510174T1 (de) 2003-05-21 2011-06-15 Alexza Pharmaceuticals Inc Schlag gezündete unabhängige heizeinheit
JP4463814B2 (ja) 2003-08-05 2010-05-19 ノボ ノルディスク アクティーゼルスカブ 新規のインスリン誘導体
US20050203001A1 (en) 2004-03-05 2005-09-15 Emisphere Technologies, Inc. Oral insulin therapies and protocol
JP2008505866A (ja) * 2004-07-09 2008-02-28 ノボ　ノルディスク　アクティーゼルスカブ インスリンを含有する薬学的製剤
CN101389650B (zh) 2005-12-28 2012-10-10 诺沃-诺迪斯克有限公司 包含酰化胰岛素和锌的组合物以及制备所述组合物的方法
JP2009544716A (ja) * 2006-07-27 2009-12-17 ノバルティス アクチエンゲゼルシャフト 肺送達のためのインスリン含有エアロゾル化可能製剤
WO2008015099A2 (en) 2006-07-31 2008-02-07 Novo Nordisk A/S Pegylated, extended insulins
CN101541830A (zh) 2006-09-22 2009-09-23 诺沃-诺迪斯克有限公司 蛋白酶抗性的胰岛素类似物
WO2008057248A2 (en) * 2006-10-26 2008-05-15 Next Breath Llc Phospholipid-based inhalation system
EP2121088B1 (de) 2007-03-09 2016-07-13 Alexza Pharmaceuticals, Inc. Erhitzungseinheit zur verwendung in einer arzneimittelabgabevorrichtung
EP2152245B1 (de) 2007-04-30 2015-12-02 Novo Nordisk A/S Verfahren zum Trocknen einer Proteinzusammensetzung, getrocknete Proteinzusammensetzung und pharmazeutische Zusammensetzungen mit dem getrockneten Protein
ES2744384T3 (es) 2007-06-13 2020-02-24 Novo Nordisk As Formulación farmacéutica que comprende un derivado de insulina
JP5762001B2 (ja) 2008-03-14 2015-08-12 ノボ・ノルデイスク・エー／エス プロテアーゼ安定化インスリンアナログ
US8691759B2 (en) 2008-03-18 2014-04-08 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
BRPI0919946A2 (pt) 2008-10-30 2016-02-16 Novo Nordisk As tratamento de diabetes melito usando injeções de insulina com frequência de injeção menor que diariamente
JP5026597B2 (ja) 2008-11-04 2012-09-12 パナソニック株式会社 測定装置、測定方法及びプログラム
DK2632478T3 (da) 2010-10-27 2019-10-07 Novo Nordisk As Behandling af diabetes melitus under anvendelse af insulinindsprøjtninger indgivet med varierende indsprøjtningsintervaller
WO2013059213A1 (en) * 2011-10-18 2013-04-25 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
BR112014025132A2 (pt) 2012-04-11 2017-07-11 Novo Nordisk As formulações de insulina
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
WO2014172488A2 (en) 2013-04-17 2014-10-23 AmideBio LLC Chemically and thermodynamically stable insulin analogues and improved methods for their production
US10137172B2 (en) 2013-04-30 2018-11-27 Novo Nordisk A/S Administration regime
BR112016007166A2 (pt) 2013-10-07 2017-09-12 Novo Nordisk As derivado de um análogo de insulina
US9898585B2 (en) 2014-01-31 2018-02-20 Aseko, Inc. Method and system for insulin management
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9892234B2 (en) 2014-10-27 2018-02-13 Aseko, Inc. Subcutaneous outpatient management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
AU2016308953B2 (en) 2015-08-20 2020-09-10 Aseko, Inc. Diabetes management therapy advisor
JP6690062B2 (ja) 2016-12-16 2020-04-28 ノヴォ ノルディスク アー／エス インスリン含有医薬組成物
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998031346A1 (en) * 1997-01-16 1998-07-23 Massachusetts Institute Of Technology Preparation of particles for inhalation
JP3764174B2 (ja) * 1997-03-20 2006-04-05 ノボ ノルディスク アクティーゼルスカブ 肺用組成物において使用するための亜鉛非含有のインスリン結晶
EP0971729B1 (de) * 1997-03-20 2002-07-03 Novo Nordisk A/S Therapeutische pulverformulierung zur pulmonaren anwendung, welche kristallines insulin enthält
ZA989644B (en) * 1997-10-24 2000-04-25 Lilly Co Eli Insoluble insulen compositions.

Also Published As

Publication number Publication date
JP2002543092A (ja) 2002-12-17
CA2370302A1 (en) 2000-11-02
WO2000064940A1 (en) 2000-11-02
EP1173482A1 (de) 2002-01-23

Similar Documents

Publication Publication Date Title
AU4450700A (en) Insulin crystals for pulmonary administration
AU2955200A (en) Cannula
AU5259100A (en) Medicament
AU1071301A (en) Pharmaceutical compounds
AU7837800A (en) Rapid infusion system
AU6489600A (en) Patient monitor
AU3068599A (en) Medication infusion set
AU2790099A (en) Frame for prone surgical positioning
AU7998900A (en) Automotive-ceiling-mounted monitor
HUP0204109A3 (en) Oral preparations for diabetes
AU2919001A (en) Syringe
AU2456500A (en) Liquid crystal compounds
AU2440700A (en) Oral arginine and insulin secretion
AU5453300A (en) Insulin crystals for pulmonary administration
AU1453901A (en) Adverse drug event monitoring
AU2225901A (en) Aspartame derivative crystals
AU2544300A (en) Immunogenic compounds
AU3065200A (en) Sleeping bag
AU1303201A (en) Alkoxyiminoalkanoic acid derivatives
AU5722900A (en) Pharmaceutical compounds
AU1541601A (en) Syringes
AU6036100A (en) New pharmaceutically active compounds
AU6480400A (en) Syringe for one-hand use
AU3133400A (en) Syringe
AU2690600A (en) 2-mercaptocarboxylic acid derivatives

Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase