AU4162101A - Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination - Google Patents

Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination

Info

Publication number
AU4162101A
AU4162101A AU4162101A AU4162101A AU4162101A AU 4162101 A AU4162101 A AU 4162101A AU 4162101 A AU4162101 A AU 4162101A AU 4162101 A AU4162101 A AU 4162101A AU 4162101 A AU4162101 A AU 4162101A
Authority
AU
Australia
Prior art keywords
pap
allele
nucleic acid
acid sequence
application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU4162101A
Other languages
English (en)
Inventor
Qiang Liu
Steve S Sommer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
City of Hope
Original Assignee
City of Hope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by City of Hope filed Critical City of Hope
Publication of AU4162101A publication Critical patent/AU4162101A/xx
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
AU4162101A 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination Pending AU4162101A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US18431500P 2000-02-23 2000-02-23
US18703500P 2000-03-06 2000-03-06
US23718000P 2000-10-03 2000-10-03
PCT/US2001/005527 WO2001062975A2 (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination

Publications (1)

Publication Number Publication Date
AU4162101A true AU4162101A (en) 2001-09-03

Family

ID=27391815

Family Applications (2)

Application Number Title Priority Date Filing Date
AU4162101A Pending AU4162101A (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination
AU2001241621A Ceased AU2001241621B2 (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (PAP): application to allele-specific amplification and nucleic acid sequence determination

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2001241621A Ceased AU2001241621B2 (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (PAP): application to allele-specific amplification and nucleic acid sequence determination

Country Status (9)

Country Link
US (2) US6534269B2 (enExample)
EP (2) EP1259646B1 (enExample)
JP (1) JP4989004B2 (enExample)
AT (1) ATE441726T1 (enExample)
AU (2) AU4162101A (enExample)
CA (1) CA2395391C (enExample)
DE (1) DE60139762D1 (enExample)
ES (1) ES2330408T3 (enExample)
WO (1) WO2001062975A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7033763B2 (en) * 2000-02-23 2006-04-25 City Of Hope Pyrophosphorolysis activated polymerization (PAP)
AUPR050700A0 (en) * 2000-10-03 2000-10-26 Id+Plus Ltd Detection method
WO2002044425A2 (en) * 2000-12-01 2002-06-06 Visigen Biotechnologies, Inc. Enzymatic nucleic acid synthesis: compositions and methods for altering monomer incorporation fidelity
CA2442169A1 (en) * 2001-03-30 2002-10-10 Applera Corporation Nucleic acid analysis using non-templated nucleotide addition
GB0110501D0 (en) 2001-04-30 2001-06-20 Secr Defence Brit Amplification process
US7141370B2 (en) * 2001-07-03 2006-11-28 The Board Of Trustees Of The Leland Stanford Junior University Bioluminescence regenerative cycle (BRC) for nucleic acid quantification
US7668697B2 (en) * 2006-02-06 2010-02-23 Andrei Volkov Method for analyzing dynamic detectable events at the single molecule level
EP2292787B1 (en) * 2002-05-10 2017-03-22 City of Hope Pyrophosphorolysis activated polymerization (PAP)
EP1753873A4 (en) 2004-03-05 2008-11-05 Ohio Med College METHOD AND COMPOSITIONS FOR THE ASSESSMENT OF NUCLEIC ACIDS AND ALLELES
WO2005106036A2 (en) 2004-04-12 2005-11-10 Medical College Of Ohio Methods and compositions for assaying analytes
US7745125B2 (en) * 2004-06-28 2010-06-29 Roche Molecular Systems, Inc. 2′-terminator related pyrophosphorolysis activated polymerization
US20060060977A1 (en) * 2004-09-22 2006-03-23 Kabushiki Kaisha Toshiba Semiconductor device
US7378260B2 (en) * 2005-04-01 2008-05-27 Applera Corporation Products and methods for reducing dye artifacts
JP5596554B2 (ja) * 2007-11-28 2014-09-24 エフ．ホフマン−ラ ロシュ アーゲー 向上したピロリン酸分解活性化重合（ｐａｐ）能力を有する変異ｄｎａポリメラーゼ
EP2644707B1 (en) 2008-04-30 2015-06-03 Integrated Dna Technologies, Inc. RNase-H-based assays utilizing modified RNA monomers
US8911948B2 (en) * 2008-04-30 2014-12-16 Integrated Dna Technologies, Inc. RNase H-based assays utilizing modified RNA monomers
CN101381766B (zh) * 2008-06-11 2012-04-18 厦门大学 一种基因稀有突变的定量检测方法
US20100112565A1 (en) * 2008-11-03 2010-05-06 Life Technologies Corporation Methods, kits, and reaction mixtures for high resolution melt genotyping
US8481685B2 (en) * 2008-11-03 2013-07-09 Kapa Biosystems Modified DNA polymerases
US8932813B2 (en) 2010-12-13 2015-01-13 Life Technologies Corporation Polymerization of nucleic acids using activation by polyphosphorolysis (APP) reactions
WO2012135053A2 (en) 2011-03-25 2012-10-04 Integrated Dna Technologies, Inc. Rnase h-based assays utilizing modified rna monomers
US10270033B2 (en) 2015-10-26 2019-04-23 Oti Lumionics Inc. Method for patterning a coating on a surface and device including a patterned coating
CN105316421B (zh) * 2015-12-01 2019-09-03 湖南宏雅基因技术有限公司 用于检测与肺癌相关的shox2基因启动子区甲基化程度的试剂盒
CN105331727B (zh) * 2015-12-01 2019-09-03 湖南宏雅基因技术有限公司 一种人外周血循环肿瘤DNA中septin 9基因甲基化的检测试剂盒
WO2018100559A1 (en) 2016-12-02 2018-06-07 Oti Lumionics Inc. Device including a conductive coating disposed over emissive regions and method therefor
JP2020518107A (ja) 2017-04-26 2020-06-18 オーティーアイ ルミオニクス インコーポレーテッドＯｔｉ Ｌｕｍｉｏｎｉｃｓ Ｉｎｃ． 表面上のコーティングをパターン化する方法およびパターン化されたコーティングを含むデバイス
KR102685809B1 (ko) 2017-05-17 2024-07-18 오티아이 루미오닉스 인크. 패턴화 코팅 위에 전도성 코팅을 선택적으로 증착시키는 방법 및 전도성 코팅을 포함하는 디바이스
US11655497B2 (en) 2017-09-26 2023-05-23 Ningbo Shining Biotechnology Co., Ltd Method of amplifying a target nucleic acid
US11751415B2 (en) 2018-02-02 2023-09-05 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
WO2019180137A1 (en) 2018-03-21 2019-09-26 F. Hoffmann-La Roche Ag Dna polymerases for efficient and effective incorporation of methylated-dntps
KR20250150689A (ko) 2018-05-07 2025-10-20 오티아이 루미오닉스 인크. 보조 전극을 제공하는 방법 및 보조 전극을 포함하는 장치
US11268140B2 (en) * 2018-06-12 2022-03-08 Shaofeng Ding Delayed pyrophosphorolysis activated polymerization
CN112889162A (zh) 2018-11-23 2021-06-01 Oti照明公司 包括光透射区域的光电装置
WO2020178804A1 (en) 2019-03-07 2020-09-10 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
KR20250110358A (ko) 2019-04-18 2025-07-18 오티아이 루미오닉스 인크. 핵 생성 억제 코팅 형성용 물질 및 이를 포함하는 디바이스
US12069938B2 (en) 2019-05-08 2024-08-20 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
KR20240134240A (ko) 2019-06-26 2024-09-06 오티아이 루미오닉스 인크. 광 회절 특성을 갖는 광 투과 영역을 포함하는 광전자 디바이스
US11832473B2 (en) 2019-06-26 2023-11-28 Oti Lumionics Inc. Optoelectronic device including light transmissive regions, with light diffraction characteristics
US12302691B2 (en) 2019-08-09 2025-05-13 Oti Lumionics Inc. Opto-electronic device including an auxiliary electrode and a partition
US11737298B2 (en) 2019-12-24 2023-08-22 Oti Lumionics Inc. Light emitting device including capping layers on respective emissive regions
CN111108860B (zh) * 2020-01-19 2024-05-14 黑龙江丰沃非凡农业科技发展有限公司 一种仿形播种机
CA3240373A1 (en) 2020-12-07 2022-06-16 Michael HELANDER Patterning a conductive deposited layer using a nucleation inhibiting coating and an underlying metallic coating
CN117904281B (zh) * 2024-01-29 2024-11-22 上海科亦生物科技有限公司 检测ugt1a1基因多态性的引物组及试剂盒与方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2020958C (en) * 1989-07-11 2005-01-11 Daniel L. Kacian Nucleic acid sequence amplification methods
US5302509A (en) 1989-08-14 1994-04-12 Beckman Instruments, Inc. Method for sequencing polynucleotides
ES2089038T3 (es) * 1990-01-26 1996-10-01 Abbott Lab Procedimiento mejorado para amplificar acidos nucleicos blanco aplicable para la reaccion en cadena de polimerasa y ligasa.
US5210015A (en) * 1990-08-06 1993-05-11 Hoffman-La Roche Inc. Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
US6228628B1 (en) * 1997-07-09 2001-05-08 Roche Molecular Systems Mutant chimeric DNA polymerase
US6270973B1 (en) * 1998-03-13 2001-08-07 Promega Corporation Multiplex method for nucleic acid detection
US6235480B1 (en) * 1998-03-13 2001-05-22 Promega Corporation Detection of nucleic acid hybrids
US6277578B1 (en) * 1998-03-13 2001-08-21 Promega Corporation Deploymerization method for nucleic acid detection of an amplified nucleic acid target
US6335162B1 (en) * 1998-03-13 2002-01-01 Promega Corporation Nucleic acid detection
US6159693A (en) * 1998-03-13 2000-12-12 Promega Corporation Nucleic acid detection
US6312902B1 (en) * 1998-03-13 2001-11-06 Promega Corporation Nucleic acid detection
US6391551B1 (en) * 1998-03-13 2002-05-21 Promega Corporation Detection of nucleic acid hybrids
US6270974B1 (en) * 1998-03-13 2001-08-07 Promega Corporation Exogenous nucleic acid detection
US7090975B2 (en) 1998-03-13 2006-08-15 Promega Corporation Pyrophosphorolysis and incorporation of nucleotide method for nucleic acid detection
US6268146B1 (en) * 1998-03-13 2001-07-31 Promega Corporation Analytical methods and materials for nucleic acid detection
US6200757B1 (en) * 1999-01-19 2001-03-13 Dade Behring Inc. Method for controlling the extension of an oligonucleotide
US6509157B1 (en) * 1999-11-05 2003-01-21 Roche Molecular Systems, Inc 3 blocked nucleic acid amplification primers
WO2001075139A1 (en) * 2000-04-03 2001-10-11 Biolink Partners, Inc. Reversible chemical modification of nucleic acids and improved method for nucleic acid hybridization

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001291513B2 (en) * 2000-10-03 2007-06-07 Id+Plus Ltd Nucleotide detection method

Also Published As

Publication number Publication date
WO2001062975A3 (en) 2002-08-29
CA2395391A1 (en) 2001-08-30
ES2330408T3 (es) 2009-12-10
EP2112233A1 (en) 2009-10-28
CA2395391C (en) 2011-08-02
EP1259646A2 (en) 2002-11-27
US20030092051A1 (en) 2003-05-15
DE60139762D1 (de) 2009-10-15
EP2112233B1 (en) 2013-10-23
US20020127554A1 (en) 2002-09-12
EP1259646B1 (en) 2009-09-02
JP4989004B2 (ja) 2012-08-01
WO2001062975A9 (en) 2002-10-24
WO2001062975A2 (en) 2001-08-30
US6534269B2 (en) 2003-03-18
US7105298B2 (en) 2006-09-12
ATE441726T1 (de) 2009-09-15
AU2001241621B2 (en) 2005-08-25
JP2003526344A (ja) 2003-09-09

Similar Documents

Publication Publication Date Title
AU4162101A (en) Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination
DK0676476T3 (da) Isotermisk nukleinsyreamplificering ved strengdeplacering
WO2001012852A3 (en) Polymerase extension at 3' terminus of pna-dna chimera
AU665952B2 (en) Methods and reagents for hepatitis C detection
EP1350841A3 (en) Thermostable or thermoactive DNA polymerase with attenuated 3'-5' exonuclease activity
DE69627698D1 (de) Eine in kaskaden verlaufende vervielfältigungsreaktion von nukleinsäuren
CA2255531A1 (en) Labeled primer for use in and detection of target nucleic acids
EP0822256A3 (en) Modified thermostable DNA polymerase, and DNA polymerase composition for nucleic acid amplification
EP1591541A3 (en) Method of nucleic acid sequencing
AU4339196A (en) Use of exonuclease and/or glycosylase as supplements to anti-polymerase antibody to increase specificity in polymerase chain reaction
EP0702090A3 (en) Coamplification of target nucleic acids using volume exclusion agent, in reaction composition, test kit and test device useful therefor
DE69518697D1 (de) Nachweis von Treponema Pallidum und Haemophilus Ducreyi
NO20000538D0 (no) Forsterkning av det spesifikke for nukleinsyreoekning ved nukleinsyrebaerer
ATE552349T1 (de) Pyrophosphorolyse-aktivierte polymerisation (pap)
WO2003085082A3 (en) Nucleic acid reactions using labels with different redox potentials
AU2003257177A1 (en) Improved compositions for in vitro amplification of nucleic acids
WO2003052115A3 (en) Post-synthesis labeling of nucleic acids and uses thereof
AU783309C (en) Oligonucleotide primers for efficient reverse transcription of hepatitis C virus (HCV) RNA and methods of use thereof
CA2213731A1 (en) Methods and reagents for typing hla class i genes
AU2001256220A1 (en) Specific multiplex analysis of nucleic acids
WO2002052040A3 (de) Verfahren für die simultane amplifikation vieler sequenzen in einer pcr-reaktion und deren markierung
ATE428802T1 (de) Nachweis von genetischen polymorphismen durch allel-spezifische amplifizierung unter benutzung von angepassten primern und darauffolgende hybridisierung
CA2339323A1 (en) Primer-specific and mispair extension assay for identifying gene variation