JP4989004B2 - 加ピロリン酸分解活性化重合(pap):アリル−特異的増幅および核酸配列決定への適応 - Google Patents

加ピロリン酸分解活性化重合(pap):アリル−特異的増幅および核酸配列決定への適応 Download PDF

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JP4989004B2
JP4989004B2 JP2001561783A JP2001561783A JP4989004B2 JP 4989004 B2 JP4989004 B2 JP 4989004B2 JP 2001561783 A JP2001561783 A JP 2001561783A JP 2001561783 A JP2001561783 A JP 2001561783A JP 4989004 B2 JP4989004 B2 JP 4989004B2
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oligonucleotide
nucleic acid
extendable
strand
pyrophosphorolysis
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JP2003526344A (ja
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リュウ,チャン
サマー,スティーヴ・エス
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City of Hope
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2001561783A 2000-02-23 2001-02-22 加ピロリン酸分解活性化重合(pap):アリル−特異的増幅および核酸配列決定への適応 Expired - Fee Related JP4989004B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US18431500P 2000-02-23 2000-02-23
US60/184,315 2000-02-23
US18703500P 2000-03-06 2000-03-06
US60/187,035 2000-03-06
US23718000P 2000-10-03 2000-10-03
US60/237,180 2000-10-03
PCT/US2001/005527 WO2001062975A2 (en) 2000-02-23 2001-02-22 Pyrophosphorolysis activated polymerization (pap): application to allele-specific amplification and nucleic acid sequence determination

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JP2003526344A5 JP2003526344A5 (enExample) 2008-04-17
JP4989004B2 true JP4989004B2 (ja) 2012-08-01

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US (2) US6534269B2 (enExample)
EP (2) EP1259646B1 (enExample)
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CN105331727B (zh) * 2015-12-01 2019-09-03 湖南宏雅基因技术有限公司 一种人外周血循环肿瘤DNA中septin 9基因甲基化的检测试剂盒
CN105316421B (zh) * 2015-12-01 2019-09-03 湖南宏雅基因技术有限公司 用于检测与肺癌相关的shox2基因启动子区甲基化程度的试剂盒
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KR20250036969A (ko) 2017-04-26 2025-03-14 오티아이 루미오닉스 인크. 표면의 코팅을 패턴화하는 방법 및 패턴화된 코팅을 포함하는 장치
KR20260023089A (ko) 2017-05-17 2026-02-20 오티아이 루미오닉스 인크. 패턴화 코팅 위에 전도성 코팅을 선택적으로 증착시키는 방법 및 전도성 코팅을 포함하는 디바이스
CN110603326B (zh) * 2017-09-26 2024-03-08 宁波尚宁生物技术有限公司 扩增靶核酸的方法
US11751415B2 (en) 2018-02-02 2023-09-05 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
ES2969883T3 (es) 2018-03-21 2024-05-23 Hoffmann La Roche ADN polimerasas para la incorporación eficiente y eficaz de dNTP metilados
US11489136B2 (en) 2018-05-07 2022-11-01 Oti Lumionics Inc. Method for providing an auxiliary electrode and device including an auxiliary electrode
US11268140B2 (en) * 2018-06-12 2022-03-08 Shaofeng Ding Delayed pyrophosphorolysis activated polymerization
JP2022508040A (ja) 2018-11-23 2022-01-19 オーティーアイ ルミオニクス インコーポレーテッド 光透過領域を含むオプトエレクトロニクスデバイス
CN116456753A (zh) 2019-03-07 2023-07-18 Oti照明公司 一种光电子器件
KR20250110358A (ko) 2019-04-18 2025-07-18 오티아이 루미오닉스 인크. 핵 생성 억제 코팅 형성용 물질 및 이를 포함하는 디바이스
WO2020225778A1 (en) 2019-05-08 2020-11-12 Oti Lumionics Inc. Materials for forming a nucleation-inhibiting coating and devices incorporating same
CN114097102B (zh) 2019-06-26 2023-11-03 Oti照明公司 包括具有光衍射特征的光透射区域的光电设备
US11832473B2 (en) 2019-06-26 2023-11-28 Oti Lumionics Inc. Optoelectronic device including light transmissive regions, with light diffraction characteristics
WO2021028800A1 (en) 2019-08-09 2021-02-18 Oti Lumionics Inc. Opto-electronic device including an auxiliary electrode and a partition
JP7403883B2 (ja) 2019-12-24 2023-12-25 オーティーアイ ルミオニクス インコーポレーテッド キャッピング層を含む発光デバイスおよびそれを製造するための方法
CN111108860B (zh) * 2020-01-19 2024-05-14 黑龙江丰沃非凡农业科技发展有限公司 一种仿形播种机
US12672476B2 (en) 2020-10-29 2026-06-30 Oti Lumionics Inc. Opto-electronic device with nanoparticle deposited layers
KR20250139404A (ko) 2020-12-07 2025-09-23 오티아이 루미오닉스 인크. 핵 생성 억제 코팅 및 하부 금속 코팅을 사용한 전도성 증착 층의 패턴화
GB202102170D0 (en) * 2021-02-16 2021-03-31 Biofidelity Ltd Polynucleotide detection
CN117904281B (zh) * 2024-01-29 2024-11-22 上海科亦生物科技有限公司 检测ugt1a1基因多态性的引物组及试剂盒与方法

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US20020127554A1 (en) 2002-09-12
WO2001062975A9 (en) 2002-10-24
US7105298B2 (en) 2006-09-12
JP2003526344A (ja) 2003-09-09
US6534269B2 (en) 2003-03-18
CA2395391C (en) 2011-08-02
WO2001062975A2 (en) 2001-08-30
WO2001062975A3 (en) 2002-08-29
EP2112233A1 (en) 2009-10-28
EP1259646A2 (en) 2002-11-27
AU4162101A (en) 2001-09-03
EP1259646B1 (en) 2009-09-02
EP2112233B1 (en) 2013-10-23
US20030092051A1 (en) 2003-05-15
CA2395391A1 (en) 2001-08-30
AU2001241621B2 (en) 2005-08-25
DE60139762D1 (de) 2009-10-15
ATE441726T1 (de) 2009-09-15
ES2330408T3 (es) 2009-12-10

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