AU3625999A - Detection of a target in a sample - Google Patents

Detection of a target in a sample

Info

Publication number
AU3625999A
AU3625999A AU36259/99A AU3625999A AU3625999A AU 3625999 A AU3625999 A AU 3625999A AU 36259/99 A AU36259/99 A AU 36259/99A AU 3625999 A AU3625999 A AU 3625999A AU 3625999 A AU3625999 A AU 3625999A
Authority
AU
Australia
Prior art keywords
target
electrodes
recognition moiety
conductive
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU36259/99A
Other languages
English (en)
Inventor
Erez Braun
Yoav Eichen
Uri Sivan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of AU3625999A publication Critical patent/AU3625999A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Detergent Compositions (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
AU36259/99A 1998-05-04 1999-05-04 Detection of a target in a sample Abandoned AU3625999A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL12432298A IL124322A (en) 1998-05-04 1998-05-04 Detection of an entity in a sample
IL124322 1998-05-04
PCT/IL1999/000232 WO1999057550A1 (en) 1998-05-04 1999-05-04 Detection of a target in a sample

Publications (1)

Publication Number Publication Date
AU3625999A true AU3625999A (en) 1999-11-23

Family

ID=11071451

Family Applications (1)

Application Number Title Priority Date Filing Date
AU36259/99A Abandoned AU3625999A (en) 1998-05-04 1999-05-04 Detection of a target in a sample

Country Status (8)

Country Link
US (2) US20120309106A1 (https=)
EP (1) EP1075656B1 (https=)
JP (1) JP4618886B2 (https=)
AT (1) ATE515693T1 (https=)
AU (1) AU3625999A (https=)
CA (3) CA2641613C (https=)
IL (1) IL124322A (https=)
WO (1) WO1999057550A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU773978B2 (en) * 1999-04-07 2004-06-10 Dennis Michael Connolly High resolution DNA detection methods and devices

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IL126776A (en) 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold
US7364920B2 (en) 1999-10-27 2008-04-29 Technion Research And Development Foundation Ltd. Method for gold deposition
DE10113550A1 (de) * 2001-03-20 2002-10-02 Infineon Technologies Ag Verfahren zum Erfassen von makromolekularen Biopolymeren mittels einer Elektrodenanordnung
US6824974B2 (en) 2001-06-11 2004-11-30 Genorx, Inc. Electronic detection of biological molecules using thin layers
US20040023253A1 (en) * 2001-06-11 2004-02-05 Sandeep Kunwar Device structure for closely spaced electrodes
CA2450109A1 (en) * 2001-06-11 2003-05-22 Genorx, Inc. Electronic detection of biological molecules using thin layers
CN100344960C (zh) * 2001-12-17 2007-10-24 清华大学 刺激动物细胞并记录其生理信号的装置及其生产使用方法
US20030186245A1 (en) * 2002-03-28 2003-10-02 Roitman Daniel B. Biomolecular sensors and detection methods utilizing photoinduced charge separation
DE10228260A1 (de) * 2002-06-25 2004-01-22 Bayer Ag Methode und Vorrichtung zum impedimetrischen Nachweis eines oder mehrerer Analyten in einer Probe
US20040166520A1 (en) * 2003-01-03 2004-08-26 Connolly D. Michael Identifying items with nucleic acid taggants
DE10322912A1 (de) * 2003-05-21 2004-12-16 Bayer Technology Services Gmbh Verfahren zum Nachweis von Nukleinsäuren
DE10327683A1 (de) * 2003-06-20 2005-01-20 Bayer Technology Services Gmbh Verfahren und Vorrichtung zum quantitativen elektrischen Nachweis von Analyten
DE10330717A1 (de) * 2003-07-03 2005-02-10 Friedrich-Schiller-Universität Jena Vorrichtung und Verfahren zum Nachweis von Analyt
US20050079598A1 (en) * 2003-10-08 2005-04-14 Davis Randall W. Apparatus and method for identification of biomolecules, in particular nucleic acid sequences, proteins, and antigens and antibodies
WO2005045409A1 (ja) * 2003-11-07 2005-05-19 Osaka Prefecture 電気抵抗型検出センサおよび検出方法
ATE388404T1 (de) * 2004-04-29 2008-03-15 Marc Ramael Verfahren und kit zum nachweis von bestandteilen in einer probe
CA2567114A1 (en) * 2004-05-28 2005-12-15 Nanogen, Inc. Nanoscale electronic detection system and methods for their manufacture
JP4873463B2 (ja) * 2006-06-30 2012-02-08 独立行政法人産業技術総合研究所 ナノギャップ電極を有する検出素子及びこれを用いた検出方法
WO2008124706A2 (en) 2007-04-06 2008-10-16 Arizona Board Of Regents Acting For And On Behalf Of Arizona State University Devices and methods for target molecule characterization
US8968540B2 (en) 2008-10-06 2015-03-03 Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of Arizona State University Trans-base tunnel reader for sequencing
JP5838474B2 (ja) 2010-02-02 2016-01-06 アリゾナ ボード オブ リージェンツ オン ビハーフ オブ アリゾナ ステート ユニバーシティ ポリマーの配列を決定するための制御されたトンネルギャップデバイス
EP2906720A4 (en) 2012-10-10 2016-06-01 Univ Arizona MOLECULAR BASED SYSTEMS AND DEVICES AND METHOD FOR PRODUCING THEM
CN113985017A (zh) 2016-01-14 2022-01-28 罗斯韦尔生物技术股份有限公司 分子传感器及相关方法
CN109071212A (zh) * 2016-01-28 2018-12-21 罗斯韦尔生物技术股份有限公司 使用大规模分子电子传感器阵列测量分析物的方法和装置
KR102763291B1 (ko) 2016-01-28 2025-02-04 로스웰 엠이 아이엔씨. 대량 병렬 ｄｎａ 시퀀싱 장치
CA3053103A1 (en) 2016-02-09 2017-08-17 Roswell Biotechnologies, Inc. Electronic label-free dna and genome sequencing
WO2017201239A1 (en) * 2016-05-18 2017-11-23 Integrated Nano-Technologies, Inc. Method for detection of a pcr product
CA3052140A1 (en) 2017-01-19 2018-07-26 Roswell Biotechnologies, Inc. Solid state sequencing devices comprising two dimensional layer materials
EP3615685B1 (en) 2017-04-25 2025-02-19 Roswell Biotechnologies, Inc Enzymatic circuits for molecular sensors
US10508296B2 (en) 2017-04-25 2019-12-17 Roswell Biotechnologies, Inc. Enzymatic circuits for molecular sensors
EP3622086A4 (en) 2017-05-09 2021-04-21 Roswell Biotechnologies, Inc BINDING PROBE CIRCUITS FOR MOLECULAR SENSORS
CN111373049A (zh) 2017-08-30 2020-07-03 罗斯威尔生命技术公司 用于dna数据存储的进行性酶分子电子传感器
EP3694990A4 (en) 2017-10-10 2022-06-15 Roswell Biotechnologies, Inc. METHODS, DEVICE AND SYSTEMS FOR AMPLIFICATION-FREE DNA DATA STORAGE
WO2019084051A1 (en) * 2017-10-23 2019-05-02 The General Hospital Corporation INTEGRATED MICROFLUIDIC ELECTRODE ARRAY SYSTEM FOR ENZYME-RELATED IMMUNO-SORBENT TITRATION FOR INTERVENTION DETECTION OF BIOMARKERS
SG11202011394WA (en) 2018-05-17 2020-12-30 Stuart Lindsay Device, system and method for direct electrical measurement of enzyme activity
JP2020041909A (ja) * 2018-09-11 2020-03-19 国立大学法人九州大学 内分泌攪乱物質等の定量方法及び定量装置
WO2020160300A2 (en) 2019-01-30 2020-08-06 Stuart Lindsay Bioelectronic circuits, systems and methods for preparing and using them
EP3953491B8 (en) 2019-04-12 2025-09-10 Roswell Biotechnologies Inc. Polycyclic aromatic bridges for molecular electronic sensors
US20230002819A1 (en) * 2019-08-22 2023-01-05 Universal Sequencing Technology Corporation Methods for Biomolecular Sensing and Detection
US12146852B2 (en) 2019-09-06 2024-11-19 Roswell Biotechnologies, Inc. Methods of fabricating nanoscale structures usable in molecular sensors and other devices
KR20230005866A (ko) * 2020-04-30 2023-01-10 아리조나 보드 오브 리젠츠 온 비하프 오브 아리조나 스테이트 유니버시티 바이오폴리머 시퀀싱 방법
US12385873B2 (en) 2020-12-25 2025-08-12 Aurangzeb Nafees Nagy Detection of target nucleic acid molecules
JP7555166B1 (ja) 2024-07-04 2024-09-24 株式会社イムノセンス 電気化学式免疫センサー

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US5137827A (en) * 1986-03-25 1992-08-11 Midwest Research Technologies, Inc. Diagnostic element for electrical detection of a binding reaction
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US5108889A (en) * 1988-10-12 1992-04-28 Thorne, Smith, Astill Technologies, Inc. Assay for determining analyte using mercury release followed by detection via interaction with aluminum
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CA2034266A1 (en) * 1990-02-27 1991-08-28 Paul A. D'orazio Thick film reagent spreading and reagent immobilization layer
US5846708A (en) * 1991-11-19 1998-12-08 Massachusetts Institiute Of Technology Optical and electrical methods and apparatus for molecule detection
IL103674A0 (en) * 1991-11-19 1993-04-04 Houston Advanced Res Center Method and apparatus for molecule detection
CA2238003C (en) * 1995-12-01 2005-02-22 Innogenetics N.V. Impedimetric detection system and method of production thereof
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IL126776A (en) * 1998-10-27 2001-04-30 Technion Res & Dev Foundation A method of investing gold

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU773978B2 (en) * 1999-04-07 2004-06-10 Dennis Michael Connolly High resolution DNA detection methods and devices

Also Published As

Publication number Publication date
EP1075656A1 (en) 2001-02-14
JP4618886B2 (ja) 2011-01-26
IL124322A0 (en) 1998-12-06
ATE515693T1 (de) 2011-07-15
US20170121761A1 (en) 2017-05-04
IL124322A (en) 2002-05-23
CA2331688A1 (en) 1999-11-11
EP1075656B1 (en) 2011-07-06
US20120309106A1 (en) 2012-12-06
CA2641613A1 (en) 1999-11-11
WO1999057550A1 (en) 1999-11-11
CA2820735A1 (en) 1999-11-11
JP2002522748A (ja) 2002-07-23
CA2641613C (en) 2013-06-25
CA2331688C (en) 2008-12-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase