AU2555792A - Disease associated human autoantibodies specific for human thyroid peroxidase - Google Patents

Disease associated human autoantibodies specific for human thyroid peroxidase

Info

Publication number
AU2555792A
AU2555792A AU25557/92A AU2555792A AU2555792A AU 2555792 A AU2555792 A AU 2555792A AU 25557/92 A AU25557/92 A AU 25557/92A AU 2555792 A AU2555792 A AU 2555792A AU 2555792 A AU2555792 A AU 2555792A
Authority
AU
Australia
Prior art keywords
tpo
antibody
thyroid peroxidase
human thyroid
human
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU25557/92A
Other languages
English (en)
Inventor
Basil Rapoport
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nichols Institute Diagnostics
Original Assignee
Nichols Institute Diagnostics
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US1992/006283 external-priority patent/WO1993003146A1/en
Application filed by Nichols Institute Diagnostics filed Critical Nichols Institute Diagnostics
Publication of AU2555792A publication Critical patent/AU2555792A/en
Assigned to NICHOLS INSTITUTE DIAGNOSTICS reassignment NICHOLS INSTITUTE DIAGNOSTICS Alteration of Name(s) of Applicant(s) under S113 Assignors: RAPOPORT, BASIL
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU25557/92A 1991-08-28 1992-08-28 Disease associated human autoantibodies specific for human thyroid peroxidase Abandoned AU2555792A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75057991A 1991-08-28 1991-08-28
US750579 1991-08-28
WOUS9206283 1992-07-30
PCT/US1992/006283 WO1993003146A1 (en) 1991-07-30 1992-07-30 Disease associated b-cell epitopes of tpo and use thereof

Publications (1)

Publication Number Publication Date
AU2555792A true AU2555792A (en) 1993-04-05

Family

ID=26784910

Family Applications (1)

Application Number Title Priority Date Filing Date
AU25557/92A Abandoned AU2555792A (en) 1991-08-28 1992-08-28 Disease associated human autoantibodies specific for human thyroid peroxidase

Country Status (8)

Country Link
US (1) US7196181B1 (show.php)
EP (1) EP0668918A1 (show.php)
JP (1) JPH07506960A (show.php)
AU (1) AU2555792A (show.php)
CA (1) CA2116453A1 (show.php)
FI (1) FI940732A7 (show.php)
NO (1) NO940668D0 (show.php)
WO (1) WO1993005072A1 (show.php)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI940732A7 (fi) 1991-08-28 1994-04-28 Nichols Inst Diagnostics Ihmisen tyroidiperoksidaasille spesifiset autovasta-aineet
GB2265713A (en) * 1992-05-16 1993-10-06 R S R Limited Assay for autoantibodies against thyroglobulin or thyroid peroxidase
JP2007501011A (ja) * 2003-08-01 2007-01-25 ジェネンテック・インコーポレーテッド 制限多様性配列を有する結合型ポリペプチド
GB0621513D0 (en) * 2006-10-30 2006-12-06 Domantis Ltd Novel polypeptides and uses thereof
CN105087512A (zh) * 2014-05-13 2015-11-25 苏州偲聚生物材料有限公司 可用于检测甲状腺疾病的蛋白质及该蛋白质的部分肽
EP4470553A3 (en) 2018-07-02 2024-12-11 Siemens Healthcare Diagnostics Inc. Novel thyroid peroxidase autoantibody immunoassay

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
NZ209308A (en) * 1983-08-30 1991-08-27 Genentech Inc Vaccine against hsv involving a truncated membrane-free derivative of a membrane-bound protein
WO1991002061A1 (en) * 1989-07-31 1991-02-21 Basil Rapaport Recombinant human thyroid peroxidase
CA2024562C (en) 1989-09-05 2000-09-26 Shinya Yamashita Cho cells transformed with a recombinant plasmid expressing human thyroid peroxidase and preparation thereof
FI940391A7 (fi) * 1991-07-30 1994-03-28 Nichols Inst Diagnostics Ihmisen tyroidiperoksidaasin B-soluepitoopit ja niiden käyttö
FI940732A7 (fi) 1991-08-28 1994-04-28 Nichols Inst Diagnostics Ihmisen tyroidiperoksidaasille spesifiset autovasta-aineet
US5998153A (en) 1992-05-19 1999-12-07 The Regents Of The University Of Michigan Thyroid peroxidase epitopic regions
GB9622772D0 (en) 1996-11-01 1997-01-08 Rsr Ltd Monitoring reactivity of thyroid peroxidase autoantibodies

Also Published As

Publication number Publication date
FI940732L (fi) 1994-04-28
FI940732A0 (fi) 1994-02-16
NO940668D0 (no) 1994-02-25
EP0668918A1 (en) 1995-08-30
CA2116453A1 (en) 1993-03-18
JPH07506960A (ja) 1995-08-03
NO940668L (show.php) 1994-04-29
EP0668918A4 (en) 1994-11-28
FI940732A7 (fi) 1994-04-28
US7196181B1 (en) 2007-03-27
WO1993005072A1 (en) 1993-03-18

Similar Documents

Publication Publication Date Title
Kipps et al. Autoantibody-associated kappa light chain variable region gene expressed in chronic lymphocytic leukemia with little or no somatic mutation. Implications for etiology and immunotherapy.
US6080588A (en) Therapeutic methods for benzodiazepine derivatives
US5871732A (en) Anti-CD4 antibody homologs useful in prophylaxis and treatment of AIDS, ARC and HIV infection
US5849506A (en) Reagents and methods for the diagnosis and treatment of diabetes and stiff man syndrome
Holst et al. Molecular cloning, genomic organization, and expression of a testicular isoform of hormone-sensitive lipase
KR20020008140A (ko) 단일클론 항체, 항원 및 악성 질환의 진단 및 치료
JPH09509160A (ja) Ｆｋ−５０６細胞質ゾル結合蛋白質
Hulett et al. Chimeric Fc receptors identify immunoglobulin‐binding regions in human FcγRII and FcϵRI
EP0721470A1 (en) Monoclonal antibodies for use in diagnosis and treatment of colorectal cancer
US6627735B2 (en) Islet cell antigen 1851
AU1997692A (en) Cloning and expression of human islet glutamic acid decarboxylase autoantigen
JP2002136292A (ja) 新規なレセプター型ホスホチロシンホスファターゼ
JPH08508877A (ja) プロテインチロシンホスファターゼｐｔｐ−ｓ３１
JPH08501934A (ja) タンパクチロシンホスファターゼのｐｔｐ−ｄサブファミリー
JPH05504683A (ja) 組み換えチロトロピン受容体
JP2001513822A (ja) 免疫性凝固を調節する方法
FR2698880A1 (fr) Procédé de production de récepteurs T solubles, produits ainsi obtenus et leur utilisation dans des compositions diagnostiques ou thérapeutiques.
US7196181B1 (en) Sequences encoding novel human thyroid peroxidase proteins and polypeptides
WO1991002061A1 (en) Recombinant human thyroid peroxidase
Leung et al. Molecular aspects and the pathological basis of primary biliary cirrhosis
JPH08510904A (ja) 新規な受容体型ホスホチロシンホスファターゼ−κ
Levy et al. Characterization of murine monoclonal anti-endothelial cell antibodies (AECA) produced by idiotypic manipulation with human AECA.
Minnerath et al. B lymphocyte recognition of cytochrome c: higher frequency of cells specific for self versus foreign antigen early in the immune response and V gene usage in the response to self antigen
WO1993003146A1 (en) Disease associated b-cell epitopes of tpo and use thereof
JPH05292994A (ja) 新規キメラ抗イディオタイプモノクローナル抗体