AU2023258011A1 - Enterococcus faecalis vaccine and uses thereof - Google Patents

Enterococcus faecalis vaccine and uses thereof Download PDF

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Publication number
AU2023258011A1
AU2023258011A1 AU2023258011A AU2023258011A AU2023258011A1 AU 2023258011 A1 AU2023258011 A1 AU 2023258011A1 AU 2023258011 A AU2023258011 A AU 2023258011A AU 2023258011 A AU2023258011 A AU 2023258011A AU 2023258011 A1 AU2023258011 A1 AU 2023258011A1
Authority
AU
Australia
Prior art keywords
polypeptide antigen
seq
recombinant
faecalis
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2023258011A
Other languages
English (en)
Inventor
Aym M. BERGES
Jeffery C. FAIRMAN
Jose A. LEMOS
Angie A. Sedra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida Research Foundation Inc
Vaxcyte Inc
Original Assignee
University of Florida
University of Florida Research Foundation Inc
Vaxcyte Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Florida, University of Florida Research Foundation Inc, Vaxcyte Inc filed Critical University of Florida
Publication of AU2023258011A1 publication Critical patent/AU2023258011A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
AU2023258011A 2022-04-18 2023-04-18 Enterococcus faecalis vaccine and uses thereof Pending AU2023258011A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263332110P 2022-04-18 2022-04-18
US63/332,110 2022-04-18
PCT/US2023/065878 WO2023205627A1 (en) 2022-04-18 2023-04-18 Enterococcus faecalis vaccine and uses thereof

Publications (1)

Publication Number Publication Date
AU2023258011A1 true AU2023258011A1 (en) 2024-10-31

Family

ID=88420684

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2023258011A Pending AU2023258011A1 (en) 2022-04-18 2023-04-18 Enterococcus faecalis vaccine and uses thereof

Country Status (7)

Country Link
US (1) US20250269004A1 (https=)
EP (1) EP4511060A1 (https=)
JP (1) JP2025514731A (https=)
KR (1) KR20250004816A (https=)
AU (1) AU2023258011A1 (https=)
TW (1) TW202404628A (https=)
WO (1) WO2023205627A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102023131065A1 (de) * 2023-11-09 2025-05-15 Consiglio Nazionale Delle Ricerche Hochstabile Antigen-präsentierende Fusionsproteine und deren Verwendung als Impfstoffkomponenten für die Therapie und/oder Prophylaxe von pathogenen Bakterien

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2289116A1 (en) * 1997-05-06 1998-11-12 Human Genome Sciences, Inc. Enterococcus faecalis polynucleotides and polypeptides
US6617156B1 (en) * 1997-08-15 2003-09-09 Lynn A. Doucette-Stamm Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
EP1177203B1 (en) * 1999-05-10 2011-10-05 The Texas A&M University System Collagen-binding proteins from enterococcal bacteria
US9839682B2 (en) * 2014-09-12 2017-12-12 Washington University Compositions and methods for the treatment and prevention of Ebp pilus-related diseases

Also Published As

Publication number Publication date
TW202404628A (zh) 2024-02-01
WO2023205627A1 (en) 2023-10-26
EP4511060A1 (en) 2025-02-26
JP2025514731A (ja) 2025-05-09
US20250269004A1 (en) 2025-08-28
KR20250004816A (ko) 2025-01-08

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