KR20250004816A - 엔테로코쿠스 패칼리스 백신 및 이의 용도 - Google Patents

엔테로코쿠스 패칼리스 백신 및 이의 용도 Download PDF

Info

Publication number
KR20250004816A
KR20250004816A KR1020247038222A KR20247038222A KR20250004816A KR 20250004816 A KR20250004816 A KR 20250004816A KR 1020247038222 A KR1020247038222 A KR 1020247038222A KR 20247038222 A KR20247038222 A KR 20247038222A KR 20250004816 A KR20250004816 A KR 20250004816A
Authority
KR
South Korea
Prior art keywords
polypeptide antigen
seq
recombinant
faecalis
immunogenic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
KR1020247038222A
Other languages
English (en)
Korean (ko)
Inventor
제프리 시. 페어맨
아임 엠. 버제스
앤지 에이. 세드라
조스 에이. 레모스
Original Assignee
박사이트, 인코포레이티드
유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 박사이트, 인코포레이티드, 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 filed Critical 박사이트, 인코포레이티드
Publication of KR20250004816A publication Critical patent/KR20250004816A/ko
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1275—Streptococcus (G)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Dermatology (AREA)
KR1020247038222A 2022-04-18 2023-04-18 엔테로코쿠스 패칼리스 백신 및 이의 용도 Pending KR20250004816A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202263332110P 2022-04-18 2022-04-18
US63/332,110 2022-04-18
PCT/US2023/065878 WO2023205627A1 (en) 2022-04-18 2023-04-18 Enterococcus faecalis vaccine and uses thereof

Publications (1)

Publication Number Publication Date
KR20250004816A true KR20250004816A (ko) 2025-01-08

Family

ID=88420684

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020247038222A Pending KR20250004816A (ko) 2022-04-18 2023-04-18 엔테로코쿠스 패칼리스 백신 및 이의 용도

Country Status (7)

Country Link
US (1) US20250269004A1 (https=)
EP (1) EP4511060A1 (https=)
JP (1) JP2025514731A (https=)
KR (1) KR20250004816A (https=)
AU (1) AU2023258011A1 (https=)
TW (1) TW202404628A (https=)
WO (1) WO2023205627A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102023131065A1 (de) * 2023-11-09 2025-05-15 Consiglio Nazionale Delle Ricerche Hochstabile Antigen-präsentierende Fusionsproteine und deren Verwendung als Impfstoffkomponenten für die Therapie und/oder Prophylaxe von pathogenen Bakterien

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2289116A1 (en) * 1997-05-06 1998-11-12 Human Genome Sciences, Inc. Enterococcus faecalis polynucleotides and polypeptides
US6617156B1 (en) * 1997-08-15 2003-09-09 Lynn A. Doucette-Stamm Nucleic acid and amino acid sequences relating to Enterococcus faecalis for diagnostics and therapeutics
EP1177203B1 (en) * 1999-05-10 2011-10-05 The Texas A&M University System Collagen-binding proteins from enterococcal bacteria
US9839682B2 (en) * 2014-09-12 2017-12-12 Washington University Compositions and methods for the treatment and prevention of Ebp pilus-related diseases

Also Published As

Publication number Publication date
AU2023258011A1 (en) 2024-10-31
TW202404628A (zh) 2024-02-01
WO2023205627A1 (en) 2023-10-26
EP4511060A1 (en) 2025-02-26
JP2025514731A (ja) 2025-05-09
US20250269004A1 (en) 2025-08-28

Similar Documents

Publication Publication Date Title
US20230062987A1 (en) Methods and compositions for immune protection against extra-intestinal pathogenic e. coli
CN101018863B (zh) 突变体肺炎链球菌溶血素蛋白质
AU2019204425A1 (en) Neisseria meningitidis compositions and methods thereof
KR20090019007A (ko) 스타필로코쿠스 감염증을 치료 및 예방하기 위한 알파-독소의 용도
CN101132810A (zh) 含有肽聚糖的糖缀合物疫苗
CN106103469B (zh) 突变型葡萄球菌抗原
US20190127426A1 (en) Neisseria meningitidis composition and methods thereof
TW200526244A (en) Formulations of hydrophobic proteins in an immunogenic composition having improved tolerability
US20240415948A1 (en) Meningococcal b recombinant vaccine
JP2021514387A (ja) ブドウ球菌抗原を含む免疫原性組成物
US8741302B2 (en) Polypeptide derived from Enterococcus and its use for vaccination
US20250269004A1 (en) Enterococcus faecalis vaccine and uses thereof
BE1024282B1 (fr) Compositions immunogènes
JP2025527246A (ja) 髄膜炎菌（Ｎｅｉｓｓｅｒｉａ ｍｅｎｉｎｇｉｔｉｄｉｓ）Ｂ群に対するアジュバント型免疫原性組成物
WO2021028402A1 (en) Immunogenic composition
US11278609B2 (en) Polypeptides derived from Enterococcus and their use for vaccination and the generation of therapeutic antibodies
WO2023232807A1 (en) Immunogenic composition

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

E13 Pre-grant limitation requested

Free format text: ST27 STATUS EVENT CODE: A-2-3-E10-E13-LIM-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

E13-X000 Pre-grant limitation requested

St.27 status event code: A-2-3-E10-E13-lim-X000

P11 Amendment of application requested

Free format text: ST27 STATUS EVENT CODE: A-2-2-P10-P11-NAP-X000 (AS PROVIDED BY THE NATIONAL OFFICE)

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000