AU2022325955A1 - Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions - Google Patents

Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions Download PDF

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Publication number
AU2022325955A1
AU2022325955A1 AU2022325955A AU2022325955A AU2022325955A1 AU 2022325955 A1 AU2022325955 A1 AU 2022325955A1 AU 2022325955 A AU2022325955 A AU 2022325955A AU 2022325955 A AU2022325955 A AU 2022325955A AU 2022325955 A1 AU2022325955 A1 AU 2022325955A1
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cell
gene
engineered cell
engineered
cells
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AU2022325955A
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Sonja SCHREPFER
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Sana Biotechnology Inc
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Sana Biotechnology Inc
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/397—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having four-membered rings, e.g. azetidine
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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  • Proteomics, Peptides & Aminoacids (AREA)
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AU2022325955A 2021-08-11 2022-08-11 Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions Abandoned AU2022325955A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202163232162P 2021-08-11 2021-08-11
US63/232,162 2021-08-11
US202263353527P 2022-06-17 2022-06-17
US63/353,527 2022-06-17
PCT/US2022/074870 WO2023019225A2 (en) 2021-08-11 2022-08-11 Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions

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AU2022325955A1 true AU2022325955A1 (en) 2024-02-08

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AU2022325955A Abandoned AU2022325955A1 (en) 2021-08-11 2022-08-11 Genetically modified cells for allogeneic cell therapy to reduce instant blood mediated inflammatory reactions

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US (1) US20250127820A1 (enExample)
EP (1) EP4384193A2 (enExample)
JP (1) JP2024535677A (enExample)
AU (1) AU2022325955A1 (enExample)
WO (1) WO2023019225A2 (enExample)

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WO2023008933A1 (ko) * 2021-07-29 2023-02-02 주식회사 툴젠 혈액 적합성을 갖는 중간엽 줄기세포, 이의 제조방법 및 용도
CN121843705A (zh) * 2023-05-03 2026-04-10 萨那生物科技公司 工程化胰岛细胞的给药和施用方法
WO2025128871A2 (en) 2023-12-13 2025-06-19 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
WO2025174765A1 (en) 2024-02-12 2025-08-21 Renagade Therapeutics Management Inc. Lipid nanoparticles comprising coding rna molecules for use in gene editing and as vaccines and therapeutic agents
GB202415025D0 (en) * 2024-10-11 2024-11-27 Ospedale San Raffaele Srl Cell

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