AU2021256845A1 - Cell classifier circuits and methods of use thereof - Google Patents

Cell classifier circuits and methods of use thereof Download PDF

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Publication number
AU2021256845A1
AU2021256845A1 AU2021256845A AU2021256845A AU2021256845A1 AU 2021256845 A1 AU2021256845 A1 AU 2021256845A1 AU 2021256845 A AU2021256845 A AU 2021256845A AU 2021256845 A AU2021256845 A AU 2021256845A AU 2021256845 A1 AU2021256845 A1 AU 2021256845A1
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target site
contiguous
mir
acid molecule
polynucleic acid
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AU2021256845A
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Bartolomeo ANGELICI
Yaakov Benenson
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ETH Zurich
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ETH Zurich
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    • C12N15/09—Recombinant DNA-technology
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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    • C12N2310/00—Structure or type of the nucleic acid
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
    • C12N2750/14141—Use of virus, viral particle or viral elements as a vector
    • C12N2750/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/001—Vector systems having a special element relevant for transcription controllable enhancer/promoter combination
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    • C12N2830/20—Vector systems having a special element relevant for transcription transcription of more than one cistron
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/50—Vector systems having a special element relevant for transcription regulating RNA stability, not being an intron, e.g. poly A signal

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  • Animal Behavior & Ethology (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
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AU2021256845A 2020-04-14 2021-04-14 Cell classifier circuits and methods of use thereof Pending AU2021256845A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US202063009736P 2020-04-14 2020-04-14
US63/009,736 2020-04-14
PCT/IB2021/000246 WO2021209813A2 (en) 2020-04-14 2021-04-14 Cell classifier circuits and methods of use thereof

Publications (1)

Publication Number Publication Date
AU2021256845A1 true AU2021256845A1 (en) 2022-11-24

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AU2021256845A Pending AU2021256845A1 (en) 2020-04-14 2021-04-14 Cell classifier circuits and methods of use thereof

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US (1) US20230133209A1 (enExample)
EP (1) EP4136241A2 (enExample)
JP (1) JP7854941B2 (enExample)
KR (1) KR20230002611A (enExample)
CN (1) CN115702247A (enExample)
AU (1) AU2021256845A1 (enExample)
CA (1) CA3179339A1 (enExample)
WO (1) WO2021209813A2 (enExample)

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* Cited by examiner, † Cited by third party
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WO2021207526A1 (en) 2020-04-09 2021-10-14 The Regents Of The University Of California Humanized notch receptors with hinge domain

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287813B1 (en) * 1999-04-23 2001-09-11 Cistronics Cell Technology Gmbh Antibiotic-based gene regulation system
KR101016561B1 (ko) * 2002-02-19 2011-02-22 다우 아그로사이언시즈 엘엘씨 신규한 스피노신 생산 폴리케타이드 신타제
WO2007014363A2 (en) 2005-07-27 2007-02-01 Genentech, Inc. Vectors for inducible expression of hairpin rna and use thereof
CA2726052A1 (en) * 2008-06-04 2009-12-10 The Board Of Regents Of The University Of Texas System Modulation of gene expression through endogenous small rna targeting of gene promoters
US8809057B2 (en) 2012-01-04 2014-08-19 Raytheon Bbn Technologies Corp. Methods of evaluating gene expression levels
CN102716498A (zh) 2012-03-12 2012-10-10 中山大学肿瘤防治中心 一种可高效高特异灭杀p53基因突变型乳腺癌细胞的药物脂质体
US10563207B2 (en) 2014-04-30 2020-02-18 Tsinghua University Modular construction of synthetic gene circuits in mammalian cells using TALE transcriptional repressors
WO2016095934A2 (en) * 2014-12-14 2016-06-23 El Abd Hisham Mohamed Magdy A novel genetic device to engineer cell behavior
CN105274059A (zh) 2015-06-15 2016-01-27 中山大学肿瘤防治中心 两株可稳定传代并保持原特性的乳腺癌干细胞系及其分离方法和应用
AU2017212713B2 (en) 2016-01-27 2023-01-19 Oncorus, Inc. Oncolytic viral vectors and uses thereof
JP2022513347A (ja) * 2018-10-11 2022-02-07 アイドゲノーシッシェ テヒニッシェ ホッホシューレ チューリッヒ 高度にコンパクトな多入力論理ゲートをコードする核酸ベクターを使用して疾患を処置する方法

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KR20230002611A (ko) 2023-01-05
CA3179339A1 (en) 2021-10-21
EP4136241A2 (en) 2023-02-22
CN115702247A (zh) 2023-02-14
WO2021209813A3 (en) 2021-12-30
JP7854941B2 (ja) 2026-05-07
WO2021209813A2 (en) 2021-10-21
US20230133209A1 (en) 2023-05-04
JP2023522025A (ja) 2023-05-26

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