AU2021217373A1 - Method of treating a solid tumor with a combination of an IL-7 protein and CAR-bearing immune cells - Google Patents
Method of treating a solid tumor with a combination of an IL-7 protein and CAR-bearing immune cells Download PDFInfo
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Classifications
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- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- A61K38/2046—IL-7
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- C—CHEMISTRY; METALLURGY
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A—HUMAN NECESSITIES
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- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterized by the route of administration
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- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the dose, timing or administration schedule
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- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K40/00 characterised by the cancer treated
- A61K2239/54—Pancreas
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/03—Fusion polypeptide containing a localisation/targetting motif containing a transmembrane segment
Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Oncology (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US202062970554P | 2020-02-05 | 2020-02-05 | |
| US62/970,554 | 2020-02-05 | ||
| PCT/US2021/016604 WO2021158783A1 (en) | 2020-02-05 | 2021-02-04 | Method of treating a solid tumor with a combination of an il-7 protein and car-bearing immune cells |
Publications (1)
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| AU2021217373A1 true AU2021217373A1 (en) | 2022-08-04 |
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| AU2021217373A Pending AU2021217373A1 (en) | 2020-02-05 | 2021-02-04 | Method of treating a solid tumor with a combination of an IL-7 protein and CAR-bearing immune cells |
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| WO2025176860A1 (en) | 2024-02-23 | 2025-08-28 | Charité - Universitätsmedizin Berlin Körperschaft des öffentlichen Rechts | Dual chimeric antigen receptor construct targeting cea and epcam |
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| GB201800298D0 (en) | 2018-01-09 | 2018-02-21 | Autolus Ltd | Method |
| AU2019215031C1 (en) * | 2018-01-31 | 2026-02-26 | Novartis Ag | Combination therapy using a chimeric antigen receptor |
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- 2021-02-04 WO PCT/US2021/016604 patent/WO2021158783A1/en not_active Ceased
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Also Published As
| Publication number | Publication date |
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| US20230210952A1 (en) | 2023-07-06 |
| KR20220137630A (ko) | 2022-10-12 |
| EP4100045A1 (en) | 2022-12-14 |
| WO2021158783A1 (en) | 2021-08-12 |
| JP2023512657A (ja) | 2023-03-28 |
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