AU2020378438A1 - Gastric residence systems for administration of active agents - Google Patents

Gastric residence systems for administration of active agents Download PDF

Info

Publication number
AU2020378438A1
AU2020378438A1 AU2020378438A AU2020378438A AU2020378438A1 AU 2020378438 A1 AU2020378438 A1 AU 2020378438A1 AU 2020378438 A AU2020378438 A AU 2020378438A AU 2020378438 A AU2020378438 A AU 2020378438A AU 2020378438 A1 AU2020378438 A1 AU 2020378438A1
Authority
AU
Australia
Prior art keywords
gastric residence
residence system
arm
linker
polymer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2020378438A
Other languages
English (en)
Inventor
David Altreuter
Estelle BEGUIN
Nupura BHISE
Nicholas DE LA TORRE
Michelle Duan
David C. DUFOUR
Tyler GRANT
Sonia HOLAR
Jie JING
Rosemary KANASTY
Erica LAI
Juan Jaramillo MONTEZCO
Saumya MOORTHY
Erick PEEKE
Erik Robert Waldemar RYDE
Marlene Schwarz
Craig SIMSES
Tammy TAI
Jeanne TRAN
Alisha Weight
Jung Hoon Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nortiva Bio Inc
Original Assignee
Nortiva Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nortiva Bio Inc filed Critical Nortiva Bio Inc
Publication of AU2020378438A1 publication Critical patent/AU2020378438A1/en
Assigned to Nortiva Bio, Inc. reassignment Nortiva Bio, Inc. Request for Assignment Assignors: LYNDRA THERAPEUTICS, INC.
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AU2020378438A 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents Pending AU2020378438A1 (en)

Applications Claiming Priority (15)

Application Number Priority Date Filing Date Title
US201962933313P 2019-11-08 2019-11-08
US201962933211P 2019-11-08 2019-11-08
US201962933210P 2019-11-08 2019-11-08
US201962933226P 2019-11-08 2019-11-08
US201962933348P 2019-11-08 2019-11-08
US62/933,211 2019-11-08
US62/933,226 2019-11-08
US62/933,210 2019-11-08
US62/933,348 2019-11-08
US62/933,313 2019-11-08
US202062992075P 2020-03-19 2020-03-19
US62/992,075 2020-03-19
US202063052905P 2020-07-16 2020-07-16
US63/052,905 2020-07-16
PCT/US2020/059541 WO2021092491A1 (en) 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents

Publications (1)

Publication Number Publication Date
AU2020378438A1 true AU2020378438A1 (en) 2022-06-02

Family

ID=75849597

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2020378438A Pending AU2020378438A1 (en) 2019-11-08 2020-11-06 Gastric residence systems for administration of active agents

Country Status (10)

Country Link
US (1) US20220387311A1 (https=)
EP (1) EP4054545A4 (https=)
JP (1) JP2022553862A (https=)
CN (1) CN115003335A (https=)
AU (1) AU2020378438A1 (https=)
BR (1) BR112022008908A2 (https=)
CA (1) CA3160665A1 (https=)
IL (1) IL292849A (https=)
MX (1) MX2022005494A (https=)
WO (1) WO2021092491A1 (https=)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020117855A1 (en) 2018-12-03 2020-06-11 Lyndra, Inc. Stomach simulating device
MX2021011314A (es) 2019-03-20 2021-12-10 Lyndra Therapeutics Inc Capsulas y recubrimientos de capsulas para formas de dosificacion de residencia gastrica.
JP2022525482A (ja) 2019-03-20 2022-05-16 リンドラ セラピューティクス, インコーポレイティド 胃内滞留剤形用のコーティング
CN116234540A (zh) 2020-07-29 2023-06-06 赛康特集团有限责任公司 具有包括交联聚(癸二酸甘油酯)的结构的形状引导控释和滞留
AU2022210426A1 (en) * 2021-01-19 2023-08-24 Nortiva Bio, Inc. Gastric residence systems for administration of risperidone
CA3248763A1 (en) * 2022-01-19 2023-07-27 Nortiva Bio, Inc. Dosage forms for gastric retention
CN115227879B (zh) * 2022-09-15 2023-01-06 北京天星博迈迪医疗器械有限公司 一种用于可降解关节球囊的组合物及其应用、一种可降解关节球囊及其制备方法
WO2024249946A2 (en) * 2023-06-02 2024-12-05 Lyndra Therapeutics, Inc. Manufacturing methods for gastric residence systems
WO2025042350A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025042349A1 (en) * 2023-08-24 2025-02-27 Junion Therapeutics (Xiamen) Co., Ltd. A gastric residence article for oral administration
WO2025148850A1 (zh) * 2024-01-09 2025-07-17 厦门君德医药科技有限公司 一种胃滞留装置
WO2025153071A1 (en) * 2024-01-18 2025-07-24 Junion Therapeutics (Xiamen) Co., Ltd. Gastric residence article for oral administration
WO2025195482A1 (zh) * 2024-03-22 2025-09-25 厦门君德医药科技有限公司 一种胃滞留装置

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9925962D0 (en) * 1999-11-02 1999-12-29 Novartis Ag Organic compounds
MX2008009125A (es) * 2006-01-18 2008-10-23 Qps Llc Composiciones farmaceuticas con estabilidad mejorada.
ES2368356T3 (es) * 2007-07-06 2011-11-16 Basf Corporation Composición de retención gástrica basada en un producto de reacción hidrosoluble procedente de un precursor que contiene un grupo vinilo.
JP5905872B2 (ja) * 2010-04-07 2016-04-20 ルピン・リミテッド タペンタドールの制御放出医薬組成物
JP5954669B2 (ja) * 2010-08-06 2016-07-20 エンドゥーシェイプ インコーポレイテッド 医療デバイス用放射線不透過性形状記憶ポリマー
WO2015191922A1 (en) * 2014-06-11 2015-12-17 Massachusetts Institute Of Technology Enteric elastomers
HK1258050A1 (zh) * 2015-10-23 2019-11-01 Lyndra Therapeutics, Inc. 用於治疗剂缓释的胃驻留系统及其使用方法
EP3386488B1 (en) * 2015-12-08 2023-09-06 Lyndra Therapeutics, Inc. Geometric configurations for gastric residence systems
AU2017268840B2 (en) * 2016-05-27 2022-02-10 Nortiva Bio, Inc. Materials architecture for gastric residence systems
US11576866B2 (en) * 2016-09-30 2023-02-14 Lyndra Therapeutics, Inc. Gastric residence systems for sustained delivery of adamantane-class drugs
US12023406B2 (en) * 2017-06-09 2024-07-02 Lyndra Therapeutics, Inc. Gastric residence systems with release rate-modulating films
AU2018337837B2 (en) * 2017-09-20 2024-03-07 Nortiva Bio, Inc. Encapsulation of gastric residence systems
KR20220002905A (ko) * 2019-03-25 2022-01-07 더글라스 파머수티클스 리미티드 서방형 약학 제제

Also Published As

Publication number Publication date
IL292849A (en) 2022-07-01
US20220387311A1 (en) 2022-12-08
WO2021092491A1 (en) 2021-05-14
MX2022005494A (es) 2022-08-11
CA3160665A1 (en) 2021-05-14
JP2022553862A (ja) 2022-12-26
BR112022008908A2 (pt) 2022-10-11
CN115003335A (zh) 2022-09-02
EP4054545A4 (en) 2024-02-14
EP4054545A1 (en) 2022-09-14

Similar Documents

Publication Publication Date Title
US20220387311A1 (en) Gastric residence systems for administration of active agents
US20220409528A1 (en) Gastric residence systems having a filament for improved gastric residence
US20240342081A1 (en) Geometric configurations for gastric residence systems
US20230190941A1 (en) Polymeric linkers for a gastric residence system
AU2018279853A1 (en) Gastric residence systems with release rate-modulating films
US20220387310A1 (en) Formulations for release-rate modulating films for gastric residence systems
US20220387312A1 (en) Gastric residence systems having arms with controlled stiffness for improved gastric residence
US20250339368A1 (en) Dosage forms for gastric retention
US20240398701A1 (en) Manufacturing methods for gastric residence systems
IL319899A (en) Risperidone dosing regimens with gastric retention systems
US20250295901A1 (en) Flexible line configurations for gastric residence systems
HK40106006A (en) Geometric configurations for gastric residence systems

Legal Events

Date Code Title Description
PC1 Assignment before grant (sect. 113)

Owner name: NORTIVA BIO, INC.

Free format text: FORMER APPLICANT(S): LYNDRA THERAPEUTICS, INC.