AU2019412791A1 - Methods for determining viral titre using Raman spectroscopy - Google Patents

Methods for determining viral titre using Raman spectroscopy Download PDF

Info

Publication number
AU2019412791A1
AU2019412791A1 AU2019412791A AU2019412791A AU2019412791A1 AU 2019412791 A1 AU2019412791 A1 AU 2019412791A1 AU 2019412791 A AU2019412791 A AU 2019412791A AU 2019412791 A AU2019412791 A AU 2019412791A AU 2019412791 A1 AU2019412791 A1 AU 2019412791A1
Authority
AU
Australia
Prior art keywords
sample
wavenumber ranges
wavenumber
vip
viral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2019412791A
Other languages
English (en)
Inventor
Marc Olivier BARADEZ
John CHURCHWELL
Damian Marshall
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cell Therapy Catapult Ltd
Original Assignee
Cell Therapy Catapult Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cell Therapy Catapult Ltd filed Critical Cell Therapy Catapult Ltd
Publication of AU2019412791A1 publication Critical patent/AU2019412791A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/65—Raman scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F17/00—Digital computing or data processing equipment or methods, specially adapted for specific functions
    • G06F17/10—Complex mathematical operations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1293—Using chemometrical methods resolving multicomponent spectra
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/12—Circuits of general importance; Signal processing
    • G01N2201/129—Using chemometrical methods
    • G01N2201/1296—Using chemometrical methods using neural networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses

Landscapes

  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Mathematical Physics (AREA)
  • Hematology (AREA)
  • Theoretical Computer Science (AREA)
  • Virology (AREA)
  • Data Mining & Analysis (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pure & Applied Mathematics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Software Systems (AREA)
  • Databases & Information Systems (AREA)
  • Mathematical Optimization (AREA)
  • Mathematical Analysis (AREA)
  • Computational Mathematics (AREA)
  • Algebra (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2019412791A 2018-12-24 2019-12-23 Methods for determining viral titre using Raman spectroscopy Abandoned AU2019412791A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1821206.8 2018-12-24
GB1821206.8A GB2580186B (en) 2018-12-24 2018-12-24 Monitoring viral titre using Raman Spectroscopy
PCT/GB2019/053695 WO2020136376A1 (en) 2018-12-24 2019-12-23 Methods for determining viral titre using raman spectroscopy

Publications (1)

Publication Number Publication Date
AU2019412791A1 true AU2019412791A1 (en) 2021-07-08

Family

ID=65364508

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2019412791A Abandoned AU2019412791A1 (en) 2018-12-24 2019-12-23 Methods for determining viral titre using Raman spectroscopy

Country Status (10)

Country Link
US (2) US11703455B2 (https=)
EP (1) EP3903096A1 (https=)
JP (1) JP7522114B2 (https=)
KR (1) KR20210104887A (https=)
CN (1) CN113490843B (https=)
AU (1) AU2019412791A1 (https=)
CA (1) CA3123168A1 (https=)
GB (1) GB2580186B (https=)
IL (1) IL284283B2 (https=)
WO (1) WO2020136376A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110609030B (zh) * 2019-10-22 2022-02-25 上海海关动植物与食品检验检疫技术中心 一种基于检出概率模型的拉曼快检性能综合评价方法
GB202010104D0 (en) * 2020-07-01 2020-08-12 Cell Therapy Catapult Ltd Method
EP4083852A1 (en) * 2021-04-30 2022-11-02 Universidad de Sevilla Virus detection and quantification method in fluid samples by digital processing diffuse optical reflectance hyperspectral images obtained in the visible and near infrared ranges
US12422367B2 (en) 2021-11-19 2025-09-23 Janssen Biotech, Inc. Methods for determination of virus titer in a sample using Raman spectroscopy
CN114628037A (zh) * 2022-02-25 2022-06-14 上海应用技术大学 一种基于深度学习卷积神经网络的新冠病毒识别预测模型
CN119256220A (zh) 2022-05-23 2025-01-03 豪夫迈·罗氏有限公司 用于区分aav颗粒血清型和aav颗粒荷载状态的基于拉曼的方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1242937A (zh) * 1998-07-28 2000-02-02 中国科学院生物物理研究所 多环醌类化合物的光敏作用杀灭血制品中艾滋病毒的方法
US20070134733A1 (en) * 2003-07-10 2007-06-14 Parallax Biosystems, Inc. Raman signature probes and their use in the detection and imaging of molecular processes and structures
US7583379B2 (en) 2005-07-28 2009-09-01 University Of Georgia Research Foundation Surface enhanced raman spectroscopy (SERS) systems and methods of use thereof
JPWO2006051847A1 (ja) * 2004-11-12 2008-05-29 財団法人新産業創造研究機構 Ｈｉｖ等のウイルス感染の有無、又はプリオン感染の有無を近赤外線分光法により検査・判定する方法、及び同方法に使用する装置
JP2005140794A (ja) * 2005-01-13 2005-06-02 E Graw An 化学物質および微生物の検出のためのラマンオプトロードプロセスおよび装置
US7889334B2 (en) * 2005-03-15 2011-02-15 University Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of bacteria and methods of use thereof
US7940387B2 (en) * 2005-03-15 2011-05-10 Univeristy Of Georgia Research Foundation, Inc. Surface enhanced Raman spectroscopy (SERS) systems for the detection of viruses and methods of use thereof
US20100279886A1 (en) * 2007-04-03 2010-11-04 University Of Rochester Two-dimensional photonic bandgap structures for ultrahigh-sensitivity biosensing
DE102008047240B4 (de) * 2008-09-11 2016-03-31 Friedrich-Schiller-Universität Jena Verfahren zur Identifikation von Einzelviren in einer Probe
US9662047B2 (en) * 2010-08-05 2017-05-30 Massachusetts Institute Of Technology Portable raman diagnostic system
TWI487910B (zh) * 2010-09-07 2015-06-11 國立成功大學 倒多角錐陣列型免標定病毒檢測基板、系統及方法
US20120316446A1 (en) * 2011-06-07 2012-12-13 Sinisa Vukelic Raman spectral analysis for disease detection and monitoring
KR101523337B1 (ko) 2012-09-20 2015-05-28 주식회사 바이오센 라만 분광법 및 케모메트릭스를 이용한 식물의 바이러스 감염에 대한 분석방법
ES2877351T3 (es) * 2013-08-07 2021-11-16 Univ Wayne State Instrumento de detección portátil basado en micro-raman y método de detección
KR20150025220A (ko) * 2013-08-28 2015-03-10 고려대학교 산학협력단 표면 증폭 라만 산란 신호를 이용한 인플루엔자 바이러스 검출 방법
JP6375509B2 (ja) * 2013-12-17 2018-08-22 パナソニックＩｐマネジメント株式会社 報知装置、空気清浄機、および、報知方法
CN105630743B (zh) * 2015-12-24 2018-05-01 浙江大学 一种光谱波数的选择方法
CN105603125B (zh) * 2016-03-09 2019-07-12 华南农业大学 一种快速检测禽病病毒的检测试剂盒及其检测方法
CN108088834B (zh) * 2017-09-13 2020-04-28 新疆大学 基于优化反向传播神经网络的包虫病血清拉曼光谱诊断仪
CN107937957B (zh) * 2017-11-23 2020-05-26 华中农业大学 表面增强拉曼基底的制备方法及该基底用于检测动物病毒

Also Published As

Publication number Publication date
US12135289B2 (en) 2024-11-05
US20230384228A1 (en) 2023-11-30
JP7522114B2 (ja) 2024-07-24
GB201821206D0 (en) 2019-02-06
EP3903096A1 (en) 2021-11-03
US11703455B2 (en) 2023-07-18
CN113490843B (zh) 2024-08-09
IL284283A (en) 2021-08-31
CA3123168A1 (en) 2020-07-02
IL284283B1 (en) 2024-03-01
GB2580186A (en) 2020-07-15
IL284283B2 (en) 2024-07-01
GB2580186B (en) 2021-09-15
CN113490843A (zh) 2021-10-08
KR20210104887A (ko) 2021-08-25
JP2022515417A (ja) 2022-02-18
WO2020136376A1 (en) 2020-07-02
US20220018782A1 (en) 2022-01-20

Similar Documents

Publication Publication Date Title
US12135289B2 (en) Methods for determining viral titre using raman spectroscopy
US20230236128A1 (en) Methods for analysing viruses using raman spectroscopy
Rohleder et al. Quantitative analysis of serum and serum ultrafiltrate by means of Raman spectroscopy
Mistek et al. Race differentiation by Raman spectroscopy of a bloodstain for forensic purposes
Driskell et al. Rapid and sensitive detection of rotavirus molecular signatures using surface enhanced Raman spectroscopy
Alexander Development of methodology based on commercialized SERS-active substrates for rapid discrimination of Poxviridae virions
JP6196220B2 (ja) 生体試料分析のための核磁気共鳴および近赤外線の使用
CN106574892A (zh) 用于确定蛋的受精和/或性别的非侵入性装置，以及相应的方法
KR20150090152A (ko) 의학적 측정 곡선들을 평가하기 위한 방법
Khristoforova et al. Combination of Raman spectroscopy and chemometrics: A review of recent studies published in the Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy Journal
Bergholt et al. Quantification of C-Reactive protein in human blood plasma using near-infrared Raman spectroscopy
Zhu et al. Raman spectroscopic measurement of relative concentrations in mixtures of oral bacteria
JP4863595B2 (ja) 混合物の分析方法
Magalhães et al. Saccharomyces cerevisiae as a Model to Confirm the Ability of FTIR to Evaluate the Presence of Protein Aggregates
Matroodi et al. Revealing acid-induced enamel damage: Deep UV Raman and multivariate analysis of hydroxyapatite loss
US12422367B2 (en) Methods for determination of virus titer in a sample using Raman spectroscopy
Kuzmanovic et al. A novel application of small-angle scattering techniques: Quality assurance testing of virus quantification technology
Grósz et al. Comparative Study of Laboratory Based Chlorophyll-A Determination Methods
Song et al. Rapid Classification of Respiratory Syncytial Virus and Sendai Virus by a Low-cost and Portable Near-infrared Spectrometer
Portable Early and Sensitive Detection of Pathogens for Public Health and Biosafety: An Example of Surveillance and Genotyping of SARS-CoV-2 in Sewage Water by Cas12a-Facilitated Portable Plasmonic Biosensor
Gao et al. Prediction of glucose concentration in a glucose-lactose mixture based on the reflective optical power at dual probe wavelengths
Chen et al. Glucose and Lactate Sensing Using Raman Spectroscopy Based Upon Iterative Pls Machine Learning
McCain et al. Large-Aperture Raman Spectroscopy for Quantitative Chemometrics
Petrich Biomedical Vibrational Spectroscopy
Eliasson et al. Rapid non-invasive quantitative assessment of pharmaceutical capsules using transmission Raman spectroscopy

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted