AU2019221691B2 - Charge-tagged nucleotides and methods of use thereof - Google Patents
Charge-tagged nucleotides and methods of use thereof Download PDFInfo
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- AU2019221691B2 AU2019221691B2 AU2019221691A AU2019221691A AU2019221691B2 AU 2019221691 B2 AU2019221691 B2 AU 2019221691B2 AU 2019221691 A AU2019221691 A AU 2019221691A AU 2019221691 A AU2019221691 A AU 2019221691A AU 2019221691 B2 AU2019221691 B2 AU 2019221691B2
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2521/00—Reaction characterised by the enzymatic activity
- C12Q2521/50—Other enzymatic activities
- C12Q2521/543—Immobilised enzyme(s)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/101—Modifications characterised by incorporating non-naturally occurring nucleotides, e.g. inosine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2535/00—Reactions characterised by the assay type for determining the identity of a nucleotide base or a sequence of oligonucleotides
- C12Q2535/122—Massive parallel sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/113—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being electroactive, e.g. redox labels
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B70/00—Tags or labels specially adapted for combinatorial chemistry or libraries, e.g. fluorescent tags or bar codes
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (1)
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| AU2022202417A AU2022202417A1 (en) | 2018-02-16 | 2022-04-12 | Charge-Tagged Nucleotides and Methods of Use Thereof |
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| US62/710,461 | 2018-02-16 | ||
| PCT/US2019/018565 WO2019161381A1 (en) | 2018-02-16 | 2019-02-19 | Charge-tagged nucleotides and methods of use thereof |
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| EP (1) | EP3752631A4 (de) |
| JP (2) | JP6938690B2 (de) |
| KR (2) | KR102330071B1 (de) |
| CN (1) | CN111164222A (de) |
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| ZA (1) | ZA201908276B (de) |
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| CA3067433C (en) * | 2018-02-16 | 2022-11-22 | Illumina, Inc. | Charge-tagged nucleotides and methods of use thereof |
| KR102429576B1 (ko) * | 2020-04-29 | 2022-08-03 | 경희대학교 산학협력단 | 전도성 태그를 이용한 dna 염기서열을 식별하는 방법 및 장치 |
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| CA2044616A1 (en) | 1989-10-26 | 1991-04-27 | Roger Y. Tsien | Dna sequencing |
| US7057026B2 (en) | 2001-12-04 | 2006-06-06 | Solexa Limited | Labelled nucleotides |
| US7414116B2 (en) | 2002-08-23 | 2008-08-19 | Illumina Cambridge Limited | Labelled nucleotides |
| US20090186343A1 (en) | 2003-01-28 | 2009-07-23 | Visigen Biotechnologies, Inc. | Methods for preparing modified biomolecules, modified biomolecules and methods for using same |
| US8637650B2 (en) | 2003-11-05 | 2014-01-28 | Genovoxx Gmbh | Macromolecular nucleotide compounds and methods for using the same |
| CA2648149A1 (en) | 2006-03-31 | 2007-11-01 | Solexa, Inc. | Systems and devices for sequence by synthesis analysis |
| AU2009251883B2 (en) | 2008-03-31 | 2014-09-11 | Pacific Biosciences Of California, Inc. | Generation of modified polymerases for improved accuracy in single molecule sequencing |
| EP2346889B1 (de) | 2008-09-03 | 2015-11-11 | Quantumdx Group Limited | Design, synthese und verwendung von synthetischen nukleotiden mit ionischen reportergruppen |
| US20100311144A1 (en) | 2009-06-05 | 2010-12-09 | Life Technologies Corporation | Mutant dna polymerases |
| WO2012009206A2 (en) | 2010-07-12 | 2012-01-19 | Pacific Biosciences Of California, Inc. | Sequencing reactions with alkali metal cations for pulse width control |
| US9164053B2 (en) | 2011-09-26 | 2015-10-20 | The Regents Of The University Of California | Electronic device for monitoring single molecule dynamics |
| JP5970049B2 (ja) * | 2013-11-28 | 2016-08-17 | 日本特殊陶業株式会社 | スパークプラグおよびその製造方法 |
| DK3460075T3 (da) * | 2014-07-15 | 2021-02-01 | Illumina Inc | Biokemisk aktiveret elektronisk anordning |
| IL255446B2 (en) | 2015-05-12 | 2024-01-01 | Illumina Inc | Field effect device and method for sequencing amino acids |
| EP3332033B1 (de) * | 2015-08-06 | 2021-04-21 | Pacific Biosciences of California, Inc. | Systeme und verfahren zur einzelmolekül-nanofet-sequenzierung |
| CN108350017B (zh) * | 2015-09-10 | 2022-03-15 | 豪夫迈·罗氏有限公司 | 多肽标记的核苷酸及其在通过纳米孔检测的核酸测序中的用途 |
| WO2017087974A1 (en) * | 2015-11-20 | 2017-05-26 | Pacific Biosciences Of California, Inc. | Protected dye-labeled reagents |
| US11225687B2 (en) * | 2016-04-04 | 2022-01-18 | The Trustees Of Columbia University In The City Of New York | DNA sequencing by synthesis with nucleotide analogues and Raman detection |
| AU2017254688B2 (en) | 2016-04-22 | 2020-05-14 | Pacific Biosciences Of California, Inc. | Nucleic acid sequencing method and system employing enhanced detection of nucleotide-specific ternary complex formation |
| EP3449011B1 (de) | 2016-04-29 | 2020-11-04 | Omniome, Inc. | Verfahren zur nukleinsäuresequenzbestimmung |
| US10655174B2 (en) * | 2016-05-27 | 2020-05-19 | Roche Sequencing Solutions, Inc. | Tagged multi-nucleotides useful for nucleic acid sequencing |
| JP6833079B2 (ja) | 2017-08-01 | 2021-02-24 | イラミーナ インコーポレーテッド | 電界効果センサ |
| CA3067433C (en) | 2018-02-16 | 2022-11-22 | Illumina, Inc. | Charge-tagged nucleotides and methods of use thereof |
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| WO2015148402A1 (en) * | 2014-03-24 | 2015-10-01 | The Trustees Of Columbia Univeristy In The City Of New York | Chemical methods for producing tagged nucleotides |
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| SA519410901B1 (ar) | 2022-07-17 |
| AU2019221691A1 (en) | 2020-01-16 |
| EP3752631A1 (de) | 2020-12-23 |
| US20200123193A1 (en) | 2020-04-23 |
| CA3067433C (en) | 2022-11-22 |
| AU2022202417A1 (en) | 2022-05-05 |
| CA3067433A1 (en) | 2019-08-22 |
| BR112019027628A2 (pt) | 2020-08-25 |
| US20210179657A1 (en) | 2021-06-17 |
| JP2020534790A (ja) | 2020-12-03 |
| RU2019141361A (ru) | 2021-06-15 |
| EP3752631A4 (de) | 2021-11-10 |
| KR20210138136A (ko) | 2021-11-18 |
| JP6938690B2 (ja) | 2021-09-22 |
| RU2751359C2 (ru) | 2021-07-13 |
| WO2019161381A1 (en) | 2019-08-22 |
| US10851131B2 (en) | 2020-12-01 |
| KR20200028344A (ko) | 2020-03-16 |
| JP2022000029A (ja) | 2022-01-04 |
| SG11201912273WA (en) | 2020-01-30 |
| WO2019161381A9 (en) | 2019-11-28 |
| IL271303A (en) | 2020-01-30 |
| MX2019015011A (es) | 2021-01-08 |
| US11578094B2 (en) | 2023-02-14 |
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