AU2018351475A1 - Novel mek-inhibitor for the treatment of viral and bacterial infections - Google Patents
Novel mek-inhibitor for the treatment of viral and bacterial infections Download PDFInfo
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- AU2018351475A1 AU2018351475A1 AU2018351475A AU2018351475A AU2018351475A1 AU 2018351475 A1 AU2018351475 A1 AU 2018351475A1 AU 2018351475 A AU2018351475 A AU 2018351475A AU 2018351475 A AU2018351475 A AU 2018351475A AU 2018351475 A1 AU2018351475 A1 AU 2018351475A1
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- virus
- infection
- pharmaceutically acceptable
- acceptable salt
- bacterial
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2024205853A AU2024205853A1 (en) | 2017-10-17 | 2024-08-16 | Novel MEK-inhibitor for the treatment of viral and bacterial infections |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LULU100487 | 2017-10-17 | ||
| LU100487 | 2017-10-17 | ||
| PCT/EP2018/078335 WO2019076947A1 (en) | 2017-10-17 | 2018-10-17 | NEW MEK INHIBITOR FOR THE TREATMENT OF VIRAL AND BACTERIAL INFECTIONS |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2024205853A Division AU2024205853A1 (en) | 2017-10-17 | 2024-08-16 | Novel MEK-inhibitor for the treatment of viral and bacterial infections |
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| EP (2) | EP3973960B1 (https=) |
| JP (3) | JP7227967B2 (https=) |
| KR (1) | KR102848960B1 (https=) |
| CN (2) | CN111479566B (https=) |
| AU (2) | AU2018351475A1 (https=) |
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| ES (2) | ES3041322T3 (https=) |
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| SI (1) | SI3697405T1 (https=) |
| WO (1) | WO2019076947A1 (https=) |
| ZA (1) | ZA202002069B (https=) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US11903917B2 (en) * | 2017-10-17 | 2024-02-20 | Atriva Therapeutics Gmbh | MEK-inhibitor for the treatment of viral and bacterial infections |
| LU101183B1 (en) * | 2019-04-16 | 2020-10-16 | Atriva Therapeutics Gmbh | Novel mek-inhibitor for the treatment of viral and bacterial infections |
| WO2021037956A1 (en) | 2019-08-27 | 2021-03-04 | Atriva Therapeutics Gmbh | Combinations of mek inhibitors with cap-dependent endonuclease inhibitors |
| EP4041212B1 (en) * | 2019-10-08 | 2025-07-23 | Atriva Therapeutics GmbH | Mek inhibitors for the treatment of hantavirus infections |
| ES2995196T3 (en) * | 2020-05-20 | 2025-02-07 | Atriva Therapeutics Gmbh | Pd-0184264 for the treatment of coronavirus infections and/or covid-19 cytokine storm |
| CN112957361B (zh) * | 2021-03-24 | 2022-07-29 | 中国科学院武汉病毒研究所 | 曲美替尼在制备抗沙粒病毒的抗病毒制剂中的应用 |
| AU2024265078A1 (en) | 2023-05-04 | 2025-12-11 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| IL326136A (en) | 2023-08-07 | 2026-03-01 | Revolution Medicines Inc | RMC-6291 for use in the treatment of a disease or disorder associated with the RAS protein |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025240847A1 (en) | 2024-05-17 | 2025-11-20 | Revolution Medicines, Inc. | Ras inhibitors |
| US20250375445A1 (en) | 2024-06-07 | 2025-12-11 | Revolution Medicines, Inc. | Methods of treating a ras protein-related disease or disorder |
| WO2025265060A1 (en) | 2024-06-21 | 2025-12-26 | Revolution Medicines, Inc. | Therapeutic compositions and methods for managing treatment-related effects |
| WO2026006747A1 (en) | 2024-06-28 | 2026-01-02 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026015825A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Use of ras inhibitor for treating pancreatic cancer |
| WO2026015796A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015790A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026015801A1 (en) | 2024-07-12 | 2026-01-15 | Revolution Medicines, Inc. | Methods of treating a ras related disease or disorder |
| WO2026050446A1 (en) | 2024-08-29 | 2026-03-05 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2026072904A2 (en) | 2024-09-26 | 2026-04-02 | Revolution Medicines, Inc. | Compositions and methods for treating lung cancer |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US6310060B1 (en) * | 1998-06-24 | 2001-10-30 | Warner-Lambert Company | 2-(4-bromo or 4-iodo phenylamino) benzoic acid derivatives and their use as MEK inhibitors |
| AU2203800A (en) * | 1999-01-07 | 2000-07-24 | Warner-Lambert Company | Antiviral method using mek inhibitors |
| JP2003504400A (ja) | 1999-07-16 | 2003-02-04 | ワーナー−ランバート・カンパニー | Ｍｅｋ阻害剤を用いた慢性痛の治療方法 |
| DE10017480A1 (de) | 2000-04-07 | 2001-10-11 | Transmit Technologietransfer | Verwendung von Substanzen, die als MEK Inhibitor wirken, zur Herstellung eines Arneimittels gegen DNA- und RNA-Viren |
| EP1467968A1 (en) | 2002-01-23 | 2004-10-20 | Warner-Lambert Company LLC | N-(4-substituted phenyl)-anthranilic acid hydroxamate esters |
| DE10300222A1 (de) * | 2003-01-03 | 2004-07-15 | MedInnova Gesellschaft für medizinische Innovationen aus akademischer Forschung mbH | Verwendung von Wirksubstanzen zur Prophylaxe und/oder Therapie von Viruserkrankungen |
| JP2007055983A (ja) * | 2005-08-26 | 2007-03-08 | Tokyo Univ Of Science | 細胞内に侵入した病原性細菌に起因する疾患の予防・改善剤 |
| EP2600862B1 (en) * | 2010-08-05 | 2016-04-20 | Case Western Reserve University | Inhibitors of erk for developmental disorders of neuronal connectivity |
| BR112015007616B1 (pt) * | 2012-10-08 | 2022-08-09 | Atriva Therapeutics Gmbh | Uso de inibidores de mek em combinação com oseltamivir, e composição farmacêutica e seu uso |
| EA039897B1 (ru) * | 2014-05-16 | 2022-03-24 | Атрива Терепьютикс Гмбх | Применение ингибитора мек для лечения коинфекции, включающей бактериальную инфекцию и инфекцию, вызванную вирусом гриппа |
| US11903917B2 (en) * | 2017-10-17 | 2024-02-20 | Atriva Therapeutics Gmbh | MEK-inhibitor for the treatment of viral and bacterial infections |
| EP4041212B1 (en) | 2019-10-08 | 2025-07-23 | Atriva Therapeutics GmbH | Mek inhibitors for the treatment of hantavirus infections |
| ES2995196T3 (en) | 2020-05-20 | 2025-02-07 | Atriva Therapeutics Gmbh | Pd-0184264 for the treatment of coronavirus infections and/or covid-19 cytokine storm |
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2018
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- 2018-10-17 LT LTEPPCT/EP2018/078335T patent/LT3697405T/lt unknown
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- 2018-10-17 AU AU2018351475A patent/AU2018351475A1/en not_active Abandoned
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- 2018-10-17 EP EP21185183.7A patent/EP3973960B1/en active Active
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- 2018-10-17 SI SI201830351T patent/SI3697405T1/sl unknown
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2020
- 2020-05-04 ZA ZA2020/02069A patent/ZA202002069B/en unknown
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2021
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2023
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2024
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- 2024-08-16 AU AU2024205853A patent/AU2024205853A1/en active Pending
- 2024-12-25 JP JP2024228526A patent/JP2025031917A/ja active Pending
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