AU2018346531A1 - Production of polyhydroxybutyrate in Wood-Ljungdahl microorganisms - Google Patents

Production of polyhydroxybutyrate in Wood-Ljungdahl microorganisms Download PDF

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Publication number
AU2018346531A1
AU2018346531A1 AU2018346531A AU2018346531A AU2018346531A1 AU 2018346531 A1 AU2018346531 A1 AU 2018346531A1 AU 2018346531 A AU2018346531 A AU 2018346531A AU 2018346531 A AU2018346531 A AU 2018346531A AU 2018346531 A1 AU2018346531 A1 AU 2018346531A1
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AU
Australia
Prior art keywords
microorganism
clostridium
coa
pseudomonas
phb
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
AU2018346531A
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English (en)
Inventor
James Bruce Yarnton Haycock BEHRENDORFF
Michael Koepke
Renato de Souza Pinto LEMGRUBER
Esteban Marcellin
Lars Nielsen
Ryan Christopher TAPPEL
Kaspar VALGEPEA
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Lanzatech Inc
Original Assignee
Lanzatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lanzatech Inc filed Critical Lanzatech Inc
Publication of AU2018346531A1 publication Critical patent/AU2018346531A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01036—Acetoacetyl-CoA reductase (1.1.1.36)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01157—3-Hydroxybutyryl-CoA dehydrogenase (1.1.1.157)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/01—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01009—Acetyl-CoA C-acetyltransferase (2.3.1.9)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AU2018346531A 2017-10-04 2018-10-04 Production of polyhydroxybutyrate in Wood-Ljungdahl microorganisms Pending AU2018346531A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762568127P 2017-10-04 2017-10-04
US62/568,127 2017-10-04
PCT/US2018/054473 WO2019071052A2 (en) 2017-10-04 2018-10-04 PRODUCTION OF POLYHYDROXYBUTYRATE IN WOOD-LJUNGDAHL MICROORGANISMS

Publications (1)

Publication Number Publication Date
AU2018346531A1 true AU2018346531A1 (en) 2020-03-19

Family

ID=65995341

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2018346531A Pending AU2018346531A1 (en) 2017-10-04 2018-10-04 Production of polyhydroxybutyrate in Wood-Ljungdahl microorganisms

Country Status (15)

Country Link
US (1) US11306333B2 (es)
EP (1) EP3692155B1 (es)
JP (2) JP7399082B2 (es)
KR (1) KR20200052377A (es)
CN (1) CN111148839B (es)
AU (1) AU2018346531A1 (es)
BR (1) BR112020006120A2 (es)
CA (1) CA3078228C (es)
DK (1) DK3692155T3 (es)
EA (1) EA202090887A1 (es)
ES (1) ES2928891T3 (es)
PL (1) PL3692155T3 (es)
PT (1) PT3692155T (es)
WO (1) WO2019071052A2 (es)
ZA (1) ZA202002296B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110317755B (zh) * 2019-06-28 2020-10-16 北京大学 一株耐低温解纤维素孟氏假单胞菌及其应用
US20220042025A1 (en) * 2020-08-06 2022-02-10 University Of Virginia Patent Foundation Compositions and methods for converting styrene to biodegradable alternatives
AU2022218205A1 (en) * 2021-02-08 2023-05-25 Lanzatech, Inc. Recombinant microorganisms and uses therefor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
KR100656529B1 (ko) * 2004-04-08 2006-12-13 한국원자력연구소 재조합 대장균 및 상기 대장균을 이용한 폴리하이드록시부티레이트의 대량 생산방법
US7803589B2 (en) * 2008-01-22 2010-09-28 Genomatica, Inc. Methods and organisms for utilizing synthesis gas or other gaseous carbon sources and methanol
WO2011043829A2 (en) 2009-10-08 2011-04-14 The Board Of Trustees Of The Leland Stanford Junior University High solids fermentation for synthesis of polyhydroxyalkanoates from gas substrates
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
WO2012149162A2 (en) * 2011-04-29 2012-11-01 Metabolix, Inc. Green process for producing polyhydroxyalkanoates and chemicals using a renewable feedstock
RU2014127528A (ru) 2012-01-06 2016-01-27 Фирмениш Са Генетически сконструированные дрожжевые клетки
JP2015000033A (ja) * 2013-06-14 2015-01-05 国立大学法人東京工業大学 ポリヒドロキシアルカン酸共重合体の製造法
EP3013966A2 (en) * 2013-06-28 2016-05-04 Metabolix, Inc. Genetically engineered methylotrophs for the production of pha biopolymers and c3, c4, and c5 biochemicals from methanol or methane as sole carbon feedstock
WO2015083769A1 (ja) 2013-12-04 2015-06-11 国立研究開発法人理化学研究所 光合成のみによるポリヒドロキシアルカン酸の生産

Also Published As

Publication number Publication date
DK3692155T3 (da) 2022-10-24
ES2928891T3 (es) 2022-11-23
CN111148839B (zh) 2024-01-30
KR20200052377A (ko) 2020-05-14
EA202090887A1 (ru) 2020-07-03
ZA202002296B (en) 2022-12-21
EP3692155A4 (en) 2021-06-30
US11306333B2 (en) 2022-04-19
EP3692155A2 (en) 2020-08-12
EP3692155B1 (en) 2022-08-17
JP7399082B2 (ja) 2023-12-15
JP2024009798A (ja) 2024-01-23
WO2019071052A3 (en) 2019-05-31
PT3692155T (pt) 2022-11-03
BR112020006120A2 (pt) 2020-11-17
PL3692155T3 (pl) 2023-05-02
CN111148839A (zh) 2020-05-12
JP2020536520A (ja) 2020-12-17
US20190119706A1 (en) 2019-04-25
CA3078228A1 (en) 2019-04-11
CA3078228C (en) 2021-04-20
WO2019071052A2 (en) 2019-04-11

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