AU2018331467A1 - Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (RSV) infections - Google Patents
Vaccines and methods of making and using vaccines for prevention of respiratory syncytial virus (RSV) infections Download PDFInfo
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- A61K2039/6043—Heat shock proteins
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- C—CHEMISTRY; METALLURGY
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- C12N2760/18534—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/18511—Pneumovirus, e.g. human respiratory syncytial virus
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
- C12N2760/20241—Use of virus, viral particle or viral elements as a vector
- C12N2760/20243—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
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- C12N2760/20271—Demonstrated in vivo effect
Landscapes
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- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
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| US201762559167P | 2017-09-15 | 2017-09-15 | |
| US62/559,167 | 2017-09-15 | ||
| PCT/US2018/051054 WO2019055768A1 (en) | 2017-09-15 | 2018-09-14 | VACCINES AND METHODS OF MAKING AND USING VACCINES FOR THE PREVENTION OF SYNCYTIAL RESPIRATORY VIRUS (RSV) INFECTIONS |
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| EP3946446A1 (en) * | 2019-04-02 | 2022-02-09 | Sanofi | Antigenic multimeric respiratory syncytial virus polypeptides |
| CN112226450B (zh) * | 2020-08-25 | 2022-10-14 | 北京交通大学 | 一种共表达呼吸道合胞病毒融合前蛋白和黏附糖蛋白的复制缺陷型腺病毒载体疫苗 |
| US20250127872A1 (en) * | 2021-09-29 | 2025-04-24 | Sk Bioscience Co., Ltd. | Recombinant live attenuated rsv vaccine strain and production method therefor |
| KR102806300B1 (ko) * | 2023-01-13 | 2025-05-14 | 클립스비엔씨 주식회사 | 호흡기 신시치아 바이러스 변이체를 포함하는 호흡기 신시치아 바이러스 백신용 융합단백질 및 이의 제조방법 |
| CN118930654A (zh) * | 2023-05-12 | 2024-11-12 | 中国科学院微生物研究所 | 一种呼吸道合胞病毒抗原制备方法和应用 |
| CN117720628A (zh) * | 2023-10-12 | 2024-03-19 | 中国科学院微生物研究所 | 一种呼吸道合胞病毒二价抗原制备方法和应用 |
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| CN1224462A (zh) * | 1996-07-15 | 1999-07-28 | 美国政府健康及人类服务部 | 从克隆的核苷酸序列制备减毒呼吸道合胞病毒疫苗的方法 |
| BR0011159A (pt) * | 1999-04-13 | 2002-07-23 | Government Of The Us Dept Of H | Método para produzir vacinas de vìrus rna de fita negativa atenuado a partir de sequências de nucleotìdeos clonados |
| AU2001264824A1 (en) * | 2000-06-01 | 2001-12-11 | St. Jude Children's Research Hospital | Vaccine and gene therapy vector and methods of use thereof |
| AU2002327755A1 (en) * | 2001-09-28 | 2003-04-14 | Rush-Presbyterian-St. Luke's Medical Center | Paramyxoviruses as gene transfer vectors to lung cells |
| CA2477235A1 (en) * | 2002-02-21 | 2003-09-04 | Medimmune Vaccines, Inc. | Recombinant parainfluenza virus expression systems and vaccines comprising heterologous antigens derived from metapneumovirus |
| DE60330966D1 (de) * | 2002-07-26 | 2010-03-04 | Canada Natural Resources | Rekombinante vesicular stomatitis viren als impstoff gegen virale hämorrhagische fieber |
| KR100999316B1 (ko) * | 2003-06-09 | 2010-12-10 | 와이어쓰 엘엘씨 | ｃＤＮＡ로부터의 비분절 네가티브 쇄 ＲＮＡ 바이러스의회수를 위한 개선된 방법 |
| ATE555208T1 (de) * | 2003-06-13 | 2012-05-15 | Apath Llc | Replikon eines negativsträngigen rna-virus |
| US8287878B2 (en) * | 2004-04-09 | 2012-10-16 | Wyeth Llc | Synergistic attenuation of vesicular stomatitis virus, vectors thereof and immunogenic compositions thereof |
| WO2008133663A2 (en) * | 2006-11-30 | 2008-11-06 | Government Of The United States Of America, As Represented By The Secretary, | Codon modified immunogenic compositions and methods of use |
| WO2009025770A2 (en) * | 2007-08-17 | 2009-02-26 | Wyeth | A heterologous prime-boost immunization regimen |
| US20090162321A1 (en) * | 2007-12-20 | 2009-06-25 | Wyeth | Methods for packaging propagation-defective vesicular stomatitis virus vectors using a stable cell line that expresses g protein |
| RU2011122615A (ru) * | 2008-11-05 | 2012-12-20 | Мерк Шарп Энд Домэ Корп. | Живой аттенуированный респираторно-синцитиальный вирус |
| KR102416194B1 (ko) * | 2014-03-01 | 2022-07-04 | 프로펙츄스 바이오사이언스, 인크. | 재조합 이스파한 바이러스 벡터 |
| CN106659777A (zh) * | 2014-06-13 | 2017-05-10 | 葛兰素史密丝克莱恩生物有限公司 | 免疫原性组合产品 |
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| WO2019055768A1 (en) | 2019-03-21 |
| KR20200096904A (ko) | 2020-08-14 |
| CA3075990A1 (en) | 2019-03-21 |
| EP3681523A1 (en) | 2020-07-22 |
| JP2020534284A (ja) | 2020-11-26 |
| US20200276297A1 (en) | 2020-09-03 |
| EP3681523A4 (en) | 2021-12-29 |
| CN111344008A (zh) | 2020-06-26 |
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