AU2018236651B2 - Liquid formulation of anti-TNF alpha antibody - Google Patents
Liquid formulation of anti-TNF alpha antibody Download PDFInfo
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- AU2018236651B2 AU2018236651B2 AU2018236651A AU2018236651A AU2018236651B2 AU 2018236651 B2 AU2018236651 B2 AU 2018236651B2 AU 2018236651 A AU2018236651 A AU 2018236651A AU 2018236651 A AU2018236651 A AU 2018236651A AU 2018236651 B2 AU2018236651 B2 AU 2018236651B2
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- Prior art keywords
- formulation
- adalimumab
- arginine
- formulations
- liquid formulation
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
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Landscapes
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| PCT/KR2018/003097 WO2018169348A1 (ko) | 2017-03-16 | 2018-03-16 | 항-tnf 알파 항체의 액상 제제 |
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| TW202102260A (zh) * | 2019-03-21 | 2021-01-16 | 美商再生元醫藥公司 | 含有抗ｉｌ－３３抗體之穩定調配物 |
| WO2021164717A1 (zh) * | 2020-02-20 | 2021-08-26 | 百奥泰生物制药股份有限公司 | 抗TNF-α的抗体制剂及其制备方法和用途 |
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| WO2015151115A1 (en) * | 2014-04-02 | 2015-10-08 | Intas Pharmaceuticals Limited | Liquid pharmaceutical composition of adalimumab |
| WO2016066688A1 (en) * | 2014-10-28 | 2016-05-06 | Richter Gedeon Nyrt. | Pharmaceutical anti-tnf-alpha antibody formulation |
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| US20140186361A1 (en) * | 2012-09-07 | 2014-07-03 | Coherus Biosciences, Inc. | Stable Aqueous Formulations of Adalimumab |
| TWI603739B (zh) * | 2010-11-11 | 2017-11-01 | 艾伯維生物技術有限責任公司 | 具有增進高濃度之抗－ＴＮＦα抗體之液體調配物 |
| UY34105A (es) * | 2011-06-03 | 2012-07-31 | Lg Life Sciences Ltd | Formulación líquida estable de etanercept |
| MX363700B (es) * | 2012-03-07 | 2019-03-29 | Cadila Healthcare Ltd | Formulaciones farmaceuticas de anticuerpos tnf-alfa. |
| BR112015017619A2 (pt) * | 2013-01-24 | 2017-11-21 | Glaxosmithkline Ip Dev Ltd | formulação líquida, uso de uma formulação, e, kit |
| JP2016515515A (ja) * | 2013-03-15 | 2016-05-30 | バイエル・ヘルスケア・エルエルシーＢａｙｅｒ ＨｅａｌｔｈＣａｒｅ ＬＬＣ | 抗プロラクチン受容体抗体製剤 |
| WO2015134406A1 (en) * | 2014-03-03 | 2015-09-11 | La Jolla Biologics, Inc. | Stable aqueous recombinant protein formulations |
| PT2946765T (pt) * | 2014-05-23 | 2016-11-10 | Ares Trading Sa | Composição farmacêutica líquida |
| US9821059B2 (en) * | 2014-10-17 | 2017-11-21 | Alteogen Inc. | Composition for stabilizing protein and pharmaceutical formulation comprising the same |
| UY36542A (es) * | 2015-01-28 | 2016-08-31 | Mabxience S A | Formulaciones farmacéuticas para anticuerpos anti-tnf-alfa |
| WO2016162819A1 (en) * | 2015-04-07 | 2016-10-13 | Lupin Limited | Stable aqueous pharmaceutical composition of anti-tnf alpha antibody |
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| WO2015151115A1 (en) * | 2014-04-02 | 2015-10-08 | Intas Pharmaceuticals Limited | Liquid pharmaceutical composition of adalimumab |
| WO2016066688A1 (en) * | 2014-10-28 | 2016-05-06 | Richter Gedeon Nyrt. | Pharmaceutical anti-tnf-alpha antibody formulation |
Also Published As
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| ZA201906696B (en) | 2020-08-26 |
| UA123847C2 (uk) | 2021-06-09 |
| JP2020510079A (ja) | 2020-04-02 |
| KR102342292B1 (ko) | 2021-12-24 |
| RU2756619C2 (ru) | 2021-10-04 |
| WO2018169348A1 (ko) | 2018-09-20 |
| JP2022097600A (ja) | 2022-06-30 |
| NZ757965A (en) | 2022-07-01 |
| PH12019502075A1 (en) | 2020-09-14 |
| CN110621303A (zh) | 2019-12-27 |
| JP7109849B2 (ja) | 2022-08-01 |
| RU2019130728A3 (uk) | 2021-04-16 |
| CO2019010860A2 (es) | 2020-01-17 |
| RU2019130728A (ru) | 2021-04-16 |
| MX2019010895A (es) | 2019-11-05 |
| MY197202A (en) | 2023-05-31 |
| KR20180106974A (ko) | 2018-10-01 |
| BR112019019162A2 (pt) | 2020-04-14 |
| KR20200096472A (ko) | 2020-08-12 |
| MA46988A1 (fr) | 2020-06-30 |
| AU2018236651A1 (en) | 2019-10-31 |
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