AU2018223976B2 - Pharmaceutical compositions for combination therapy - Google Patents
Pharmaceutical compositions for combination therapy Download PDFInfo
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- AU2018223976B2 AU2018223976B2 AU2018223976A AU2018223976A AU2018223976B2 AU 2018223976 B2 AU2018223976 B2 AU 2018223976B2 AU 2018223976 A AU2018223976 A AU 2018223976A AU 2018223976 A AU2018223976 A AU 2018223976A AU 2018223976 B2 AU2018223976 B2 AU 2018223976B2
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- fibrosis
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- liver
- diseases
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- A61K31/4164—1,3-Diazoles
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
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- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P3/00—Drugs for disorders of the metabolism
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
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- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
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EP17305213 | 2017-02-24 | ||
PCT/EP2018/054588 WO2018154081A1 (en) | 2017-02-24 | 2018-02-23 | Pharmaceutical compositions for combination therapy |
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AU2018223976A1 AU2018223976A1 (en) | 2019-09-05 |
AU2018223976B2 true AU2018223976B2 (en) | 2023-08-17 |
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EP (1) | EP3585384A1 (ru) |
JP (1) | JP2020510651A (ru) |
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CN (1) | CN110418641A (ru) |
AU (1) | AU2018223976B2 (ru) |
BR (1) | BR112019017314A2 (ru) |
CA (1) | CA3051977A1 (ru) |
EA (1) | EA201991990A1 (ru) |
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PH (1) | PH12019501820A1 (ru) |
SG (1) | SG11201907084VA (ru) |
WO (1) | WO2018154081A1 (ru) |
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US20220133666A1 (en) * | 2016-03-31 | 2022-05-05 | Genfit | Methods of treatment of cholestatic diseases |
CA3018132C (en) * | 2016-03-31 | 2024-02-13 | Genfit | Use of elafibranor in the treatment of a cholestatic disease |
Citations (3)
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WO2011064350A1 (en) * | 2009-11-26 | 2011-06-03 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
WO2016040860A1 (en) * | 2014-09-12 | 2016-03-17 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
WO2017048322A1 (en) * | 2015-09-16 | 2017-03-23 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
Family Cites Families (8)
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PE20030329A1 (es) | 2001-08-08 | 2003-05-12 | Takeda Chemical Industries Ltd | Compuesto biciclico con actividad antagonista de ccr5 y produccion del mismo |
FR2841900B1 (fr) | 2002-07-08 | 2007-03-02 | Genfit S A | Nouveaux derives de 1,3-diphenylprop-2-en-1-one substitues, preparation et utilisations |
ES2633766T3 (es) * | 2011-10-28 | 2017-09-25 | Lumena Pharmaceuticals Llc | Inhibidores de reciclaje de ácido biliar para el tratamiento de enfermedades de hígado colestático pediátrico |
KR20160132489A (ko) * | 2014-03-21 | 2016-11-18 | 토비라 쎄라퓨틱스, 인크. | 섬유증 치료용 세니크리바이록 |
CA3018132C (en) * | 2016-03-31 | 2024-02-13 | Genfit | Use of elafibranor in the treatment of a cholestatic disease |
MX2018012285A (es) * | 2016-04-11 | 2019-02-07 | Genfit | Metodos de tratamiento para enfermedades colestasicas y fibroticas. |
JOP20190040A1 (ar) * | 2016-09-14 | 2019-03-10 | Novartis Ag | توليفة من ناهضات fxr |
SG11201906041QA (en) * | 2017-01-27 | 2019-08-27 | Genfit | Pharmaceutical compositions for combination therapy |
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Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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WO2011064350A1 (en) * | 2009-11-26 | 2011-06-03 | Genfit | Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders |
WO2016040860A1 (en) * | 2014-09-12 | 2016-03-17 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
WO2017048322A1 (en) * | 2015-09-16 | 2017-03-23 | Tobira Therapeutics, Inc. | Cenicriviroc combination therapy for the treatment of fibrosis |
Also Published As
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US20190388394A1 (en) | 2019-12-26 |
MX2019009909A (es) | 2019-10-14 |
CA3051977A1 (en) | 2018-08-30 |
IL268708A (en) | 2019-10-31 |
WO2018154081A1 (en) | 2018-08-30 |
JP2020510651A (ja) | 2020-04-09 |
SG11201907084VA (en) | 2019-09-27 |
BR112019017314A2 (pt) | 2020-04-14 |
KR20190119097A (ko) | 2019-10-21 |
CN110418641A (zh) | 2019-11-05 |
US11590108B2 (en) | 2023-02-28 |
AU2018223976A1 (en) | 2019-09-05 |
KR102633249B1 (ko) | 2024-02-02 |
EA201991990A1 (ru) | 2020-04-07 |
PH12019501820A1 (en) | 2020-09-14 |
IL268708B (en) | 2022-05-01 |
EP3585384A1 (en) | 2020-01-01 |
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