SG11201907084VA - Pharmaceutical compositions for combination therapy - Google Patents

Pharmaceutical compositions for combination therapy

Info

Publication number
SG11201907084VA
SG11201907084VA SG11201907084VA SG11201907084VA SG11201907084VA SG 11201907084V A SG11201907084V A SG 11201907084VA SG 11201907084V A SG11201907084V A SG 11201907084VA SG 11201907084V A SG11201907084V A SG 11201907084VA SG 11201907084V A SG11201907084V A SG 11201907084VA
Authority
SG
Singapore
Prior art keywords
international
loos
pct
danel
leonard
Prior art date
Application number
SG11201907084VA
Inventor
Emeline Descamps
Robert Walczak
Carole Belanger
Benoît Noel
Original Assignee
Genfit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genfit filed Critical Genfit
Publication of SG11201907084VA publication Critical patent/SG11201907084VA/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41781,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

WO 18/ 15408 1 Al (12) INTERNATIONAL APPLICATION PUBLISHED UNDER THE PATENT COOPERATION TREATY (PCT) (19) World Intellectual Property Organization International Bureau (43) International Publication Date 30 August 2018 (30.08.2018) WIP0 I PCT ill mu °mons °nolo OH 100 Ho oinio oimIE (10) International Publication Number WO 2018/154081 Al (51) International Patent Classification: A61K 31/41 78 (2006.01) A61K 31/192 (2006.01) A61K 45/06 (2006.01) (21) International Application Number: PCT/EP2018/054588 (22) International Filing Date: 23 February 2018 (23.02.2018) (25) Filing Language: English (26) Publication Language: English (30) Priority Data: 17305213.5 24 February 2017 (24.02.2017) EP (71) Applicant: GENFIT [FR/FR]; 885 avenue Eugene Avinee, 59120 LOOS (FR). (72) Inventors: DESCAMPS, Emeline; 9 me Leonard Danel, 59120 LOOS (FR). WALCZAK, Robert; Residence Parc d'Isly, 13B me Delezenne, 59000 LILLE (FR). BE- LANGER, Carole; 3 Allee du Verger, 59910 BONDUES (FR). NOEL, Benoit; 9 me Leonard Danel, 59120 Loos (FR). (74) Agent: CABINET BECKER ET ASSOCIES; 25, rue Louis le Grand, 75002 PARIS (FR). (81) Designated States (unless otherwise indicated, for every kind of national protection available): AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BN, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DJ, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IR, IS, JO, JP, KE, KG, KH, KN, KP, KR, KW, KZ, LA, LC, LK, LR, LS, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PA, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SA, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW. (84) Designated States (unless otherwise indicated, for every kind of regional protection available): ARIPO (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, ST, SZ, TZ, UG, ZM, ZW), Eurasian (AM, AZ, BY, KG, KZ, RU, TJ, TM), European (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR), OAPI (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, KM, ML, MR, NE, SN, TD, TG). Published: with international search report (Art. 21(3)) with sequence listing part of description (Rule 5.2(a)) (54) Title: PHARMACEUTICAL COMPOSITIONS FOR COMBINATION THERAPY (57) : The present invention relates to a combination of active ingredients for use in the treatment of diseases.
SG11201907084VA 2017-02-24 2018-02-23 Pharmaceutical compositions for combination therapy SG11201907084VA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP17305213 2017-02-24
PCT/EP2018/054588 WO2018154081A1 (en) 2017-02-24 2018-02-23 Pharmaceutical compositions for combination therapy

Publications (1)

Publication Number Publication Date
SG11201907084VA true SG11201907084VA (en) 2019-09-27

Family

ID=58231557

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201907084VA SG11201907084VA (en) 2017-02-24 2018-02-23 Pharmaceutical compositions for combination therapy

Country Status (14)

Country Link
US (1) US11590108B2 (en)
EP (1) EP3585384A1 (en)
JP (1) JP2020510651A (en)
KR (1) KR102633249B1 (en)
CN (1) CN110418641A (en)
AU (1) AU2018223976B2 (en)
BR (1) BR112019017314A2 (en)
CA (1) CA3051977A1 (en)
EA (1) EA201991990A1 (en)
IL (1) IL268708B (en)
MX (1) MX2019009909A (en)
PH (1) PH12019501820A1 (en)
SG (1) SG11201907084VA (en)
WO (1) WO2018154081A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4233910A3 (en) * 2016-03-31 2024-01-17 Genfit Methods of treatment of cholestatic diseases
US12053445B2 (en) * 2016-03-31 2024-08-06 Genfit Methods of treatment of cholestatic diseases

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2206702T3 (en) 2001-08-08 2012-02-13 Tobira Therapeutics Inc Bicyclic compound, preparation and use thereof
FR2841900B1 (en) 2002-07-08 2007-03-02 Genfit S A NOVEL SUBSTITUTED 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES, PREPARATION AND USES
KR101962209B1 (en) * 2009-11-26 2019-03-26 장피트 Use of 1,3-diphenylprop-2-en-1-one derivatives for treating liver disorders
JP6217938B2 (en) * 2011-10-28 2017-10-25 ルメナ ファーマシューティカルズ エルエルシー Bile acid recirculation inhibitors for the treatment of cholestatic liver disease in children
SG11201607859SA (en) * 2014-03-21 2016-10-28 Tobira Therapeutics Inc Cenicriviroc for the treatment of fibrosis
RU2723559C2 (en) * 2014-09-12 2020-06-16 Тобира Терапьютикс, Инк. Combined therapy with application of cenicriviroc for fibrosis treatment
JP2018532720A (en) 2015-09-16 2018-11-08 トビラ セラピューティクス, インコーポレイテッド Senicribiroc combination therapy for the treatment of fibrosis
EP4233910A3 (en) 2016-03-31 2024-01-17 Genfit Methods of treatment of cholestatic diseases
CN109152760B (en) 2016-04-11 2022-09-23 基恩菲特公司 Methods of treating cholestatic and fibrotic diseases
JOP20190040A1 (en) * 2016-09-14 2019-03-10 Novartis Ag Combination of fxr agonists
SG11201906041QA (en) 2017-01-27 2019-08-27 Genfit Pharmaceutical compositions for combination therapy

Also Published As

Publication number Publication date
MX2019009909A (en) 2019-10-14
KR20190119097A (en) 2019-10-21
AU2018223976B2 (en) 2023-08-17
CN110418641A (en) 2019-11-05
EP3585384A1 (en) 2020-01-01
US11590108B2 (en) 2023-02-28
CA3051977A1 (en) 2018-08-30
AU2018223976A1 (en) 2019-09-05
IL268708A (en) 2019-10-31
IL268708B (en) 2022-05-01
PH12019501820A1 (en) 2020-09-14
US20190388394A1 (en) 2019-12-26
BR112019017314A2 (en) 2020-04-14
WO2018154081A1 (en) 2018-08-30
JP2020510651A (en) 2020-04-09
EA201991990A1 (en) 2020-04-07
KR102633249B1 (en) 2024-02-02

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