AU2017339577B2 - Immunogenic compounds for cancer therapy - Google Patents

Immunogenic compounds for cancer therapy Download PDF

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Publication number
AU2017339577B2
AU2017339577B2 AU2017339577A AU2017339577A AU2017339577B2 AU 2017339577 B2 AU2017339577 B2 AU 2017339577B2 AU 2017339577 A AU2017339577 A AU 2017339577A AU 2017339577 A AU2017339577 A AU 2017339577A AU 2017339577 B2 AU2017339577 B2 AU 2017339577B2
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AU
Australia
Prior art keywords
peptide
present
antigenic
cancer
seq
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AU2017339577A
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AU2017339577A1 (en
Inventor
Laurent Chene
Alban MATHIEU
Matthieu PICHAUD
Francesco STROZZI
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Enterome SA
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Enterome SA
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Publication of AU2017339577A1 publication Critical patent/AU2017339577A1/en
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Publication of AU2017339577B2 publication Critical patent/AU2017339577B2/en
Priority to AU2022200872A priority Critical patent/AU2022200872B2/en
Priority to AU2023222999A priority patent/AU2023222999B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0011—Cancer antigens
    • A61K39/001102—Receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AU2017339577A 2016-10-07 2017-10-09 Immunogenic compounds for cancer therapy Active AU2017339577B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2022200872A AU2022200872B2 (en) 2016-10-07 2022-02-10 Immunogenic compounds for cancer therapy
AU2023222999A AU2023222999B2 (en) 2016-10-07 2023-09-01 Immunogenic compounds for cancer therapy

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16192948.4 2016-10-07
EP16192948 2016-10-07
PCT/EP2017/075673 WO2018065623A2 (en) 2016-10-07 2017-10-09 Immunogenic compounds for cancer therapy

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2022200872A Division AU2022200872B2 (en) 2016-10-07 2022-02-10 Immunogenic compounds for cancer therapy

Publications (2)

Publication Number Publication Date
AU2017339577A1 AU2017339577A1 (en) 2019-05-02
AU2017339577B2 true AU2017339577B2 (en) 2021-12-02

Family

ID=57123864

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2017339577A Active AU2017339577B2 (en) 2016-10-07 2017-10-09 Immunogenic compounds for cancer therapy
AU2022200872A Active AU2022200872B2 (en) 2016-10-07 2022-02-10 Immunogenic compounds for cancer therapy
AU2023222999A Active AU2023222999B2 (en) 2016-10-07 2023-09-01 Immunogenic compounds for cancer therapy

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2022200872A Active AU2022200872B2 (en) 2016-10-07 2022-02-10 Immunogenic compounds for cancer therapy
AU2023222999A Active AU2023222999B2 (en) 2016-10-07 2023-09-01 Immunogenic compounds for cancer therapy

Country Status (9)

Country Link
US (2) US11478537B2 (enExample)
EP (1) EP3522915A2 (enExample)
JP (3) JP7116278B2 (enExample)
KR (2) KR102622188B1 (enExample)
CN (2) CN110022893B (enExample)
AU (3) AU2017339577B2 (enExample)
CA (1) CA3039322A1 (enExample)
IL (3) IL302345B2 (enExample)
WO (1) WO2018065623A2 (enExample)

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IL302345B2 (en) 2016-10-07 2024-12-01 Enterome S A Immunogenic compounds for cancer therapy
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Also Published As

Publication number Publication date
JP7648311B2 (ja) 2025-03-18
CN110022893B (zh) 2023-12-29
JP2019534884A (ja) 2019-12-05
IL302345B2 (en) 2024-12-01
EP3522915A2 (en) 2019-08-14
WO2018065623A3 (en) 2018-05-31
IL296165B2 (en) 2023-10-01
WO2018065623A2 (en) 2018-04-12
US12263210B2 (en) 2025-04-01
US20230201322A1 (en) 2023-06-29
IL265751A (en) 2019-05-30
CA3039322A1 (en) 2018-04-12
CN110022893A (zh) 2019-07-16
IL265751B2 (en) 2023-02-01
CN117801066A (zh) 2024-04-02
KR20190066028A (ko) 2019-06-12
JP2023156414A (ja) 2023-10-24
IL302345A (en) 2023-06-01
IL296165A (en) 2022-11-01
AU2023222999B2 (en) 2025-07-24
JP2022120137A (ja) 2022-08-17
AU2023222999A1 (en) 2023-09-21
IL296165B1 (en) 2023-06-01
AU2017339577A1 (en) 2019-05-02
AU2022200872B2 (en) 2023-06-29
JP7116278B2 (ja) 2022-08-10
KR102622188B1 (ko) 2024-01-05
AU2022200872A1 (en) 2022-03-03
KR20240007316A (ko) 2024-01-16
IL302345B1 (en) 2024-08-01
US20200113983A1 (en) 2020-04-16
KR102686875B1 (ko) 2024-07-19
US11478537B2 (en) 2022-10-25
JP7331207B2 (ja) 2023-08-22
IL265751B (en) 2022-10-01

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