AU2017295038B2 - 5-hydroxytryptamine 1B receptor-stimulating agent for skin and/or hair repair - Google Patents
5-hydroxytryptamine 1B receptor-stimulating agent for skin and/or hair repair Download PDFInfo
- Publication number
- AU2017295038B2 AU2017295038B2 AU2017295038A AU2017295038A AU2017295038B2 AU 2017295038 B2 AU2017295038 B2 AU 2017295038B2 AU 2017295038 A AU2017295038 A AU 2017295038A AU 2017295038 A AU2017295038 A AU 2017295038A AU 2017295038 B2 AU2017295038 B2 AU 2017295038B2
- Authority
- AU
- Australia
- Prior art keywords
- skin
- hair
- vortioxetine
- receptor
- hydroxytryptamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/145—Amines having sulfur, e.g. thiurams (>N—C(S)—S—C(S)—N< and >N—C(S)—S—S—C(S)—N<), Sulfinylamines (—N=SO), Sulfonylamines (—N=SO2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4933—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having sulfur as an exocyclic substituent, e.g. pyridinethione
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/002—Preparations for repairing the hair, e.g. hair cure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
- A61K2800/884—Sequential application
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Birds (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IB2016001136 | 2016-07-15 | ||
| IBPCT/IB2016/001136 | 2016-07-15 | ||
| PCT/EP2017/067791 WO2018011382A1 (en) | 2016-07-15 | 2017-07-13 | 5-hydroxytryptamine 1b receptor-stimulating agent for skin and/or hair repair |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2017295038A1 AU2017295038A1 (en) | 2019-01-24 |
| AU2017295038B2 true AU2017295038B2 (en) | 2022-09-22 |
Family
ID=56787641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2017295038A Expired - Fee Related AU2017295038B2 (en) | 2016-07-15 | 2017-07-13 | 5-hydroxytryptamine 1B receptor-stimulating agent for skin and/or hair repair |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20190290641A1 (https=) |
| EP (1) | EP3484462B1 (https=) |
| JP (1) | JP2019524723A (https=) |
| KR (1) | KR20190038840A (https=) |
| CN (1) | CN110022869A (https=) |
| AU (1) | AU2017295038B2 (https=) |
| BR (1) | BR112019000706A8 (https=) |
| CA (1) | CA3030054A1 (https=) |
| MX (1) | MX386989B (https=) |
| WO (1) | WO2018011382A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX386470B (es) | 2015-07-17 | 2025-03-18 | Pasteur Institut | Agente estimulador del receptor 5-hidroxi triptamina 1b para usarse como un promotor de la autorrenovación y/o diferenciación de células satélite. |
| US11013830B2 (en) | 2015-11-20 | 2021-05-25 | Institut Pasteur | 5-hydroxytryptamine 1B receptor-stimulating agent for enhancing in vivo engraftment potential |
| CA3101420A1 (en) * | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| CN115919860B (zh) * | 2022-12-05 | 2023-11-10 | 中国药科大学 | 氟班色林在制备治疗雄激素脱发药物中的用途 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003029232A1 (en) * | 2001-10-04 | 2003-04-10 | H. Lundbeck A/S | Phenyl-piperazine derivatives as serotonin reuptake inhibitors |
| WO2007148341A2 (en) * | 2006-06-22 | 2007-12-27 | Ramot At Tel Aviv University Ltd. | Novel serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| WO2008078353A1 (en) * | 2006-12-22 | 2008-07-03 | Medestea Internazionale S.P.A. | A novel use of antidepressant compounds and related compositions |
| WO2011048496A1 (en) * | 2009-10-23 | 2011-04-28 | Fortuderm, Ltd. | Triptans for the treatment of psoriasis |
| WO2014190063A1 (en) * | 2013-05-21 | 2014-11-27 | Wynberg Jason B | Methods for the treatment of premature ejaculation |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63203625A (ja) | 1987-02-19 | 1988-08-23 | Kao Corp | 5α−リダクタ−ゼ阻害剤 |
| FR2739553B1 (fr) | 1995-10-06 | 1998-01-02 | Oreal | Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
| FR2758263B1 (fr) * | 1997-01-16 | 1999-12-17 | Oreal | Utilisation d'un antagoniste ou d'un agoniste de serotonine specifiques respectivement du recepteur 5ht2 et 5ht1d dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue |
| FR2778558B1 (fr) | 1998-05-12 | 2001-02-16 | Oreal | Utilisation d'inhibiteur de metalloproteinases pour induire et/ou stimuler la croissance des cheveux ou des poils et/ou freiner leur chute |
| ES2147538B1 (es) | 1999-01-29 | 2001-04-01 | Revlon Consumer Prod Corp | Una locion capilar con propiedades mejoradas en su accion protectora del cabello y preventiva de su caida, y de reduccion de los efectos externos de la alopecia androgenetica y con ello de la caida del cabello. |
| JP3441665B2 (ja) | 1999-02-04 | 2003-09-02 | 株式会社資生堂 | (2−置換オキシフェニル)アルカンアミド誘導体及び養毛剤、皮膚外用剤 |
| US20060052405A1 (en) | 2000-07-19 | 2006-03-09 | Knowles W R | Hair loss prevention |
| FR2812192B1 (fr) | 2000-07-28 | 2003-01-31 | Oreal | Utilisation d'antagonistes de recepteur des prostaglandines ep-3 comme agent cosmetique permettant d'attenuer, de diminuer ou d'arreter la chute des cheveux et des poils |
| DE50012119D1 (de) * | 2000-09-22 | 2006-04-13 | Perlei Medical Producte Gmbh | Verwendung von Antifibrinolytika für die Präparation und Herstellung von Tupfern, Kompressen oder Pflaster |
| DK1262177T3 (da) | 2001-05-31 | 2006-11-20 | Pfizer Prod Inc | Medicinsk brug af thyromimetiske forbindelser til behandling af hårtab og kompositioner |
| EP1435899B1 (en) | 2001-09-28 | 2009-03-11 | LG Household & Health Care Ltd. | A composition for promoting hair growth |
| US6860042B2 (en) | 2002-07-19 | 2005-03-01 | Walker-Dawson Interests, Inc. | Excavation system employing a jet pump |
| US20070292461A1 (en) * | 2003-08-04 | 2007-12-20 | Foamix Ltd. | Oleaginous pharmaceutical and cosmetic foam |
| DE60323533D1 (de) | 2002-11-12 | 2008-10-23 | Warner Lambert Co | Methode zur stimulierung von haarwuchs auf der basis von benzopyranen |
| BRPI0406778A (pt) | 2003-01-17 | 2006-01-17 | Warner Lambert Co | Antagonistas de receptores de androgênio |
| PT1636236E (pt) | 2003-05-22 | 2013-12-16 | Nerviano Medical Sciences Srl | Derivados de pirazol-quinazolina, processo para sua preparação e sua utilização como inibidores de cinase |
| US20050118282A1 (en) | 2003-09-16 | 2005-06-02 | Aphios Corporation | Compositions and methods for inhibiting 5-alpha reductase |
| AR041407A1 (es) | 2003-09-26 | 2005-05-18 | Nestor Alberto Kerner | Oligonucleotidos antiandrogenos utilizables en el tratamiento de patologias dermatologicas relacionadas con el metabolismo de los androgenos, sus composiciones farmaceuticas y sus usos y metodos de tratamiento |
| US20060009430A1 (en) | 2004-07-01 | 2006-01-12 | Kelly Gregory J | Composition for the prevention and treatment of the detrimental effects of dihydrotestosterone |
| EP1781598A1 (en) | 2004-07-08 | 2007-05-09 | Warner-Lambert Company LLC | Androgen modulators |
| DE202006007482U1 (de) | 2006-05-10 | 2006-07-20 | Sentner, Thomas | Leuchtmöbel |
| EP2044043B2 (en) * | 2006-06-16 | 2021-03-03 | H. Lundbeck A/S | 1- ý[- (2, 4-dimethylphenylsulfanyl) -phenyl]piperazine hydrobromide as a compound with combined serotonin reuptake, 5-ht3 and 5-ht1a activity for the treatment of cognitive impairment |
| FR2903984B1 (fr) | 2006-07-24 | 2008-10-03 | Genfit Sa | Derives d'imidazolones substitues, preparation et utilisations |
| WO2008084286A2 (en) * | 2006-10-25 | 2008-07-17 | Arterial Remodeling Technologies, S.A. | Method for expansion and deployment of polymeric structures including stents |
| US7737149B2 (en) | 2006-12-21 | 2010-06-15 | Astrazeneca Ab | N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-4-(3,5-dimethylpiperazin-1-yl)benzamide and salts thereof |
| ITTO20060918A1 (it) * | 2006-12-22 | 2008-06-23 | Chiara Cesano | Composizione cosmetica e farmaceutica e mezzo di coltura per la rigenerazione del tessuto cutaneo, e relativi usi |
| PT2585470T (pt) | 2010-06-23 | 2017-03-06 | Hanmi Science Co Ltd | Novos derivados fundidos de pirimidina para inibição da actividade da tirosina cinase |
| AU2013305563B2 (en) * | 2012-08-24 | 2018-09-27 | Integurx Therapeutics, Llc | Chemical compositions and methods for enhancing transdermal delivery of therapeutic agents |
| US9399039B1 (en) * | 2015-06-30 | 2016-07-26 | University Of South Florida | Inhibitors of the FKBP51 protein from a high-throughput drug screen and methods of use |
-
2017
- 2017-07-13 BR BR112019000706A patent/BR112019000706A8/pt not_active IP Right Cessation
- 2017-07-13 AU AU2017295038A patent/AU2017295038B2/en not_active Expired - Fee Related
- 2017-07-13 US US16/316,557 patent/US20190290641A1/en not_active Abandoned
- 2017-07-13 JP JP2019501427A patent/JP2019524723A/ja active Pending
- 2017-07-13 WO PCT/EP2017/067791 patent/WO2018011382A1/en not_active Ceased
- 2017-07-13 KR KR1020197004019A patent/KR20190038840A/ko not_active Ceased
- 2017-07-13 MX MX2019000600A patent/MX386989B/es unknown
- 2017-07-13 EP EP17742997.4A patent/EP3484462B1/en active Active
- 2017-07-13 CN CN201780055993.4A patent/CN110022869A/zh active Pending
- 2017-07-13 CA CA3030054A patent/CA3030054A1/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003029232A1 (en) * | 2001-10-04 | 2003-04-10 | H. Lundbeck A/S | Phenyl-piperazine derivatives as serotonin reuptake inhibitors |
| WO2007148341A2 (en) * | 2006-06-22 | 2007-12-27 | Ramot At Tel Aviv University Ltd. | Novel serotonin reuptake inhibitors as drugs having peripheral-system-restricted activity |
| WO2008078353A1 (en) * | 2006-12-22 | 2008-07-03 | Medestea Internazionale S.P.A. | A novel use of antidepressant compounds and related compositions |
| WO2011048496A1 (en) * | 2009-10-23 | 2011-04-28 | Fortuderm, Ltd. | Triptans for the treatment of psoriasis |
| WO2014190063A1 (en) * | 2013-05-21 | 2014-11-27 | Wynberg Jason B | Methods for the treatment of premature ejaculation |
Non-Patent Citations (2)
| Title |
|---|
| ALEX MALININ, BENJAMIN OSHRINE, VICTOR SEREBRUANY: "Treatment with selective serotonin reuptake inhibitors for enhancing wound healing", MEDICAL HYPOTHESES, EDEN PRESS, PENRITH., US, vol. 63, no. 1, 1 January 2004 (2004-01-01), US , pages 103 - 109, XP055348687, ISSN: 0306-9877, DOI: 10.1016/j.mehy.2003.10.021 * |
| NGUYEN: JOURNAL OF INVESTIGATIVE DERMATOLOGY, S133 PUBLISHED IN ISSUE: MAY 2016, 1 May 2016 (2016-05-01), XP055348757, Retrieved from the Internet [retrieved on 20170222] * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018011382A1 (en) | 2018-01-18 |
| CN110022869A (zh) | 2019-07-16 |
| KR20190038840A (ko) | 2019-04-09 |
| EP3484462A1 (en) | 2019-05-22 |
| EP3484462B1 (en) | 2022-12-14 |
| US20190290641A1 (en) | 2019-09-26 |
| BR112019000706A2 (pt) | 2019-05-07 |
| MX2019000600A (es) | 2019-06-13 |
| JP2019524723A (ja) | 2019-09-05 |
| CA3030054A1 (en) | 2018-01-18 |
| MX386989B (es) | 2025-03-19 |
| AU2017295038A1 (en) | 2019-01-24 |
| BR112019000706A8 (pt) | 2022-12-06 |
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