AU2017277626A1 - A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof - Google Patents

A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof Download PDF

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Publication number
AU2017277626A1
AU2017277626A1 AU2017277626A AU2017277626A AU2017277626A1 AU 2017277626 A1 AU2017277626 A1 AU 2017277626A1 AU 2017277626 A AU2017277626 A AU 2017277626A AU 2017277626 A AU2017277626 A AU 2017277626A AU 2017277626 A1 AU2017277626 A1 AU 2017277626A1
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AU
Australia
Prior art keywords
blood sample
post
stabilizing composition
analyte
stabilizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2017277626A
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English (en)
Inventor
M. Rohan Fernando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cf Genome LLC
Original Assignee
Cf Genome LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cf Genome LLC filed Critical Cf Genome LLC
Publication of AU2017277626A1 publication Critical patent/AU2017277626A1/en
Abandoned legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0226Physiologically active agents, i.e. substances affecting physiological processes of cells and tissue to be preserved, e.g. anti-oxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40Concentrating samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Physiology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AU2017277626A 2016-06-08 2017-06-07 A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof Abandoned AU2017277626A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662347441P 2016-06-08 2016-06-08
US62/347,441 2016-06-08
PCT/US2017/036413 WO2017214310A1 (en) 2016-06-08 2017-06-07 A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof

Publications (1)

Publication Number Publication Date
AU2017277626A1 true AU2017277626A1 (en) 2019-01-24

Family

ID=60578993

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017277626A Abandoned AU2017277626A1 (en) 2016-06-08 2017-06-07 A chemical composition to stabilize extracellular vesicles in a blood sample and method of use thereof

Country Status (6)

Country Link
US (1) US20190254273A1 (ja)
EP (1) EP3468361A4 (ja)
JP (1) JP2019527363A (ja)
AU (1) AU2017277626A1 (ja)
CA (1) CA3024996A1 (ja)
WO (1) WO2017214310A1 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3124698A1 (en) * 2018-12-27 2020-07-02 Streck, Inc. Methods of preparing samples for proteomic analysis
WO2022006260A1 (en) * 2020-07-01 2022-01-06 Streck, Inc. Methods of preparing samples for proteomic analysis
CN114107005A (zh) * 2020-12-08 2022-03-01 河南驼人医疗器械研究院有限公司 一种含有游离脱氧核糖核酸稳定剂的采血管
CN115702637B (zh) * 2021-08-13 2024-01-30 郑州安图生物工程股份有限公司 一种胃泌素17血液样本的保护剂

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5008202A (en) * 1988-11-29 1991-04-16 Sequoia Turner Corporation Blood diluent for red blood cell analysis
US5281700A (en) * 1992-08-11 1994-01-25 The Regents Of The University Of California Method of recovering endothelial membrane from tissue and applications thereof
FR2777782B1 (fr) * 1998-04-22 2001-05-18 Alexandre Marti Solution pour la preparation d'une substance pharmaceutique pour le diagnostic et/ou le traitement de lesions tissulaires
US6139878A (en) * 1998-04-27 2000-10-31 Aventis Behring, Llc Method for preparing a diafiltered stabilized blood product
US6913932B2 (en) * 2002-08-23 2005-07-05 Beckman Coulter, Inc. Formaldehyde-ammonium salt complexes for the stabilization of blood cells
GB0808413D0 (en) * 2008-05-09 2008-06-18 Univ Nottingham Stabilisation of blood cell conjugates
EP3103883A1 (en) * 2009-11-09 2016-12-14 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
US20150225712A1 (en) * 2012-08-21 2015-08-13 Qiagen Gmbh Method for isolating nucleic acids from a formaldehyde releaser stabilized sample
US10091984B2 (en) * 2013-07-24 2018-10-09 Streck, Inc. Compositions and methods for stabilizing circulating tumor cells
WO2015048566A1 (en) * 2013-09-26 2015-04-02 The General Hospital Corporation Methods of isolating extracellular vesicles

Also Published As

Publication number Publication date
WO2017214310A1 (en) 2017-12-14
US20190254273A1 (en) 2019-08-22
EP3468361A4 (en) 2020-02-19
JP2019527363A (ja) 2019-09-26
WO2017214310A9 (en) 2018-03-01
EP3468361A1 (en) 2019-04-17
CA3024996A1 (en) 2017-12-14

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Date Code Title Description
MK1 Application lapsed section 142(2)(a) - no request for examination in relevant period