AU2017275184B2 - Fusion protein for improving protein expression from target mRNA - Google Patents

Fusion protein for improving protein expression from target mRNA Download PDF

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Publication number
AU2017275184B2
AU2017275184B2 AU2017275184A AU2017275184A AU2017275184B2 AU 2017275184 B2 AU2017275184 B2 AU 2017275184B2 AU 2017275184 A AU2017275184 A AU 2017275184A AU 2017275184 A AU2017275184 A AU 2017275184A AU 2017275184 B2 AU2017275184 B2 AU 2017275184B2
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AU2017275184A1 (en
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Takahiro Nakamura
Yusuke Yagi
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Kyushu University NUC
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Kyushu University NUC
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU2017275184A 2016-06-03 2017-05-30 Fusion protein for improving protein expression from target mRNA Active AU2017275184B2 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201662345252P 2016-06-03 2016-06-03
US62/345,252 2016-06-03
JP2016120524 2016-06-17
JP2016-120524 2016-06-17
PCT/JP2017/020076 WO2017209122A1 (ja) 2016-06-03 2017-05-30 標的ｍＲＮＡからのタンパク質発現量を向上させるための融合タンパク質

Publications (2)

Publication Number Publication Date
AU2017275184A1 AU2017275184A1 (en) 2018-12-13
AU2017275184B2 true AU2017275184B2 (en) 2021-05-06

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ID=60478518

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AU2017275184A Active AU2017275184B2 (en) 2016-06-03 2017-05-30 Fusion protein for improving protein expression from target mRNA

Country Status (5)

Country Link
KR (1) KR102407776B1 (ko)
AU (1) AU2017275184B2 (ko)
CA (1) CA3026340A1 (ko)
SG (1) SG11201810606TA (ko)
WO (1) WO2017209122A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114729017A (zh) 2019-05-29 2022-07-08 日商基因编辑力股份有限公司 Ppr蛋白的有效制作方法及其应用
BR112021023937A2 (pt) 2019-05-29 2022-04-19 Editforce Inc Motivo ppr, uso do motivo ppr, proteína capaz de se ligar a um ácido nucleico alvo, proteína de fusão, métodos para modificar uma proteína ppr contendo o motivo ppr, para manipular um ácido nucleico, para detectar um ácido nucleico e para produzir um organismo, ácido nucleico, vetor, e, célula

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006217871A (ja) * 2005-02-10 2006-08-24 Tokyo Univ Of Science 遺伝子の転写調節方法
JP2009544296A (ja) * 2006-07-21 2009-12-17 サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、（セーエヌエルエス） バイオリアクター生産性を向上させるポジティブサイトモジュリン
WO2013058404A1 (ja) * 2011-10-21 2013-04-25 国立大学法人九州大学 Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用
JP2016039810A (ja) * 2013-04-22 2016-03-24 国立大学法人九州大学 Ｐｐｒモチーフを利用したｄｎａ結合性タンパク質およびその利用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013128413A (ja) * 2010-03-11 2013-07-04 Kyushu Univ Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の改変方法
JP2015221026A (ja) * 2014-05-23 2015-12-10 公立大学法人名古屋市立大学 人工合成ｍＲＮＡの翻訳効率化方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006217871A (ja) * 2005-02-10 2006-08-24 Tokyo Univ Of Science 遺伝子の転写調節方法
JP2009544296A (ja) * 2006-07-21 2009-12-17 サントル、ナショナール、ド、ラ、ルシェルシュ、シアンティフィク、（セーエヌエルエス） バイオリアクター生産性を向上させるポジティブサイトモジュリン
WO2013058404A1 (ja) * 2011-10-21 2013-04-25 国立大学法人九州大学 Pprモチーフを利用したrna結合性蛋白質の設計方法及びその利用
JP2016039810A (ja) * 2013-04-22 2016-03-24 国立大学法人九州大学 Ｐｐｒモチーフを利用したｄｎａ結合性タンパク質およびその利用

Also Published As

Publication number Publication date
WO2017209122A1 (ja) 2017-12-07
KR20190015374A (ko) 2019-02-13
KR102407776B1 (ko) 2022-06-10
SG11201810606TA (en) 2018-12-28
CA3026340A1 (en) 2017-12-07
AU2017275184A1 (en) 2018-12-13

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