CA3026340A1 - Fusion protein for improving protein expression level from target mrna - Google Patents
Fusion protein for improving protein expression level from target mrna Download PDFInfo
- Publication number
- CA3026340A1 CA3026340A1 CA3026340A CA3026340A CA3026340A1 CA 3026340 A1 CA3026340 A1 CA 3026340A1 CA 3026340 A CA3026340 A CA 3026340A CA 3026340 A CA3026340 A CA 3026340A CA 3026340 A1 CA3026340 A1 CA 3026340A1
- Authority
- CA
- Canada
- Prior art keywords
- asparagine
- ppr
- aspartic acid
- binding
- mrna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Botany (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662345252P | 2016-06-03 | 2016-06-03 | |
| US62/345,252 | 2016-06-03 | ||
| JP2016-120524 | 2016-06-17 | ||
| JP2016120524 | 2016-06-17 | ||
| PCT/JP2017/020076 WO2017209122A1 (ja) | 2016-06-03 | 2017-05-30 | 標的ｍＲＮＡからのタンパク質発現量を向上させるための融合タンパク質 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA3026340A1 true CA3026340A1 (en) | 2017-12-07 |
Family
ID=60478518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA3026340A Pending CA3026340A1 (en) | 2016-06-03 | 2017-05-30 | Fusion protein for improving protein expression level from target mrna |
Country Status (5)
| Country | Link |
|---|---|
| KR (1) | KR102407776B1 (ko) |
| AU (1) | AU2017275184B2 (ko) |
| CA (1) | CA3026340A1 (ko) |
| SG (1) | SG11201810606TA (ko) |
| WO (1) | WO2017209122A1 (ko) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020241876A1 (ja) | 2019-05-29 | 2020-12-03 | エディットフォース株式会社 | 効率的なｐｐｒタンパク質の作製方法及びその利用 |
| CA3142303A1 (en) | 2019-05-29 | 2020-12-03 | Editforce, Inc. | Ppr protein causing less aggregation and use of the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4665190B2 (ja) * | 2005-02-10 | 2011-04-06 | 学校法人東京理科大学 | 遺伝子の転写調節方法 |
| EP2049565B1 (en) * | 2006-07-21 | 2015-01-28 | Centre National De La Recherche Scientifique (Cnrs) | Positive cytomodulines to improve bioreactor productivity. |
| JP2013128413A (ja) | 2010-03-11 | 2013-07-04 | Kyushu Univ | Ｐｐｒモチーフを利用したｒｎａ結合性蛋白質の改変方法 |
| EP2784157B1 (en) * | 2011-10-21 | 2019-09-18 | Kyushu University, National University Corporation | Design method for rna-binding protein using ppr motif, and use thereof |
| CA2910050A1 (en) | 2013-04-22 | 2014-10-30 | Kyushu University, National University Corporation | Dna-binding protein using ppr motif, and use thereof |
| JP2015221026A (ja) * | 2014-05-23 | 2015-12-10 | 公立大学法人名古屋市立大学 | 人工合成ｍＲＮＡの翻訳効率化方法 |
-
2017
- 2017-05-30 KR KR1020187037821A patent/KR102407776B1/ko active IP Right Grant
- 2017-05-30 AU AU2017275184A patent/AU2017275184B2/en active Active
- 2017-05-30 WO PCT/JP2017/020076 patent/WO2017209122A1/ja unknown
- 2017-05-30 CA CA3026340A patent/CA3026340A1/en active Pending
- 2017-05-30 SG SG11201810606TA patent/SG11201810606TA/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201810606TA (en) | 2018-12-28 |
| AU2017275184A1 (en) | 2018-12-13 |
| WO2017209122A1 (ja) | 2017-12-07 |
| KR20190015374A (ko) | 2019-02-13 |
| AU2017275184B2 (en) | 2021-05-06 |
| KR102407776B1 (ko) | 2022-06-10 |
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