AU2017268248A1 - Aqueous biomolecule coupling on CO2-plasma-activated surfaces - Google Patents

Aqueous biomolecule coupling on CO2-plasma-activated surfaces Download PDF

Info

Publication number
AU2017268248A1
AU2017268248A1 AU2017268248A AU2017268248A AU2017268248A1 AU 2017268248 A1 AU2017268248 A1 AU 2017268248A1 AU 2017268248 A AU2017268248 A AU 2017268248A AU 2017268248 A AU2017268248 A AU 2017268248A AU 2017268248 A1 AU2017268248 A1 AU 2017268248A1
Authority
AU
Australia
Prior art keywords
entity
substrate
ixlo
plasma
contacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2017268248A
Other languages
English (en)
Inventor
Thomas Doyle
Donald E. Ingber
Daniel Christopher Leslie
Melissa RODAS
Michael Super
Anna Waterhouse
Alexander L. Watters
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Harvard University
Original Assignee
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard University filed Critical Harvard University
Publication of AU2017268248A1 publication Critical patent/AU2017268248A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K17/00Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02Peptides being immobilised on, or in, an organic carrier
    • C07K17/08Peptides being immobilised on, or in, an organic carrier the carrier being a synthetic polymer
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726Lectins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L25/00Compositions of, homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring; Compositions of derivatives of such polymers
    • C08L25/02Homopolymers or copolymers of hydrocarbons
    • C08L25/04Homopolymers or copolymers of styrene
    • C08L25/06Polystyrene
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L83/00Compositions of macromolecular compounds obtained by reactions forming in the main chain of the macromolecule a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon only; Compositions of derivatives of such polymers
    • C08L83/04Polysiloxanes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/544Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
    • G01N33/545Synthetic resin
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
    • C08K5/04Oxygen-containing compounds
    • C08K5/05Alcohols; Metal alcoholates
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08LCOMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2203/00Applications
    • C08L2203/02Applications for biomedical use

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • External Artificial Organs (AREA)
AU2017268248A 2016-05-16 2017-05-16 Aqueous biomolecule coupling on CO2-plasma-activated surfaces Abandoned AU2017268248A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662336940P 2016-05-16 2016-05-16
US62/336,940 2016-05-16
PCT/US2017/032928 WO2017201064A1 (en) 2016-05-16 2017-05-16 Aqueous biomolecule coupling on co2-plasma-activated surfaces

Publications (1)

Publication Number Publication Date
AU2017268248A1 true AU2017268248A1 (en) 2018-12-13

Family

ID=59054182

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2017268248A Abandoned AU2017268248A1 (en) 2016-05-16 2017-05-16 Aqueous biomolecule coupling on CO2-plasma-activated surfaces

Country Status (9)

Country Link
US (1) US11919971B2 (https=)
EP (1) EP3458483A1 (https=)
JP (2) JP7163192B2 (https=)
KR (1) KR20190020668A (https=)
CN (1) CN109476764A (https=)
AU (1) AU2017268248A1 (https=)
CA (1) CA3024490A1 (https=)
IL (2) IL263017B (https=)
WO (1) WO2017201064A1 (https=)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014144325A1 (en) * 2013-03-15 2014-09-18 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
KR102257967B1 (ko) * 2017-12-11 2021-05-28 주식회사 엘지화학 내열 수지 조성물 및 이를 이용한 자동차용 스포일러
CN110082531B (zh) * 2019-04-11 2022-04-22 南方医科大学南方医院 一种肿瘤外泌体纳米荧光检测试剂盒及其应用
CN111855498B (zh) * 2020-06-24 2023-04-07 同济大学 一种基于表面能理论的沥青混合料拌和温度确定方法
US20240001019A1 (en) * 2020-07-31 2024-01-04 Miraki Innovation Think Tank Llc Mbl-coated substrates having anti-thrombogenic properties
CN112961246B (zh) * 2021-02-07 2023-04-07 西南大学 一种纳米微球抗生物膜肽cramp及其制备方法和应用
CN115300608B (zh) * 2021-05-06 2023-06-02 四川大学 一种利用甘露糖结合凝集素阻断新冠病毒感染的方法
CN114643050B (zh) * 2022-05-19 2022-08-23 浙江晟格生物科技有限公司 一种提高乳糖异构化产率的复合催化剂、制备方法及应用
CN116448996B (zh) * 2023-03-22 2023-11-21 卡秋(江苏)生物科技有限公司 一种串珠结构的多聚酶-抗体复合物的制备方法
CN120696139B (zh) * 2025-07-21 2026-04-17 广东韩研活性炭科技股份有限公司 一种表面改性的高效吸附ak活性炭及其应用

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5270199A (en) 1987-08-20 1993-12-14 The Children's Medical Center Corporation Human mannose-binding protein
US5132108A (en) 1990-11-08 1992-07-21 Cordis Corporation Radiofrequency plasma treated polymeric surfaces having immobilized anti-thrombogenic agents
DE60030173T2 (de) 1999-05-14 2007-08-23 Steffen Thiel Neue Indikationen für Mannan-binding Lectin (MBL) zur Behandlung von immungeschwächten Patienten
DE102007021386A1 (de) * 2007-05-04 2008-11-06 Christof-Herbert Diener Kurztaktniederdruckplasmaanlage
SG10201503351RA (en) 2010-01-19 2015-06-29 Harvard College Engineered Opsonin for Pathogen Detection and Treatment
CN103649240B (zh) 2011-01-19 2016-09-14 哈佛学院院长等 具有高压稳定性、光学透明性以及自修复特征的光滑表面
AU2012284097B2 (en) 2011-07-18 2017-08-03 President And Fellows Of Harvard College Engineered microbe-targeting molecules and uses thereof
US20150328062A9 (en) * 2011-11-10 2015-11-19 Covidien Lp Hydrophilic medical devices
CN104254579B (zh) 2012-01-10 2018-05-29 哈佛学院院长等 用于流体和固体排斥性的表面的改性
EP3327090A1 (en) * 2012-07-18 2018-05-30 President and Fellows of Harvard College Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
US20140100131A1 (en) * 2012-10-10 2014-04-10 Xiaohu Gao Methods and Reagents for Target Isolation from a Sample
WO2014144325A1 (en) 2013-03-15 2014-09-18 President And Fellows Of Harvard College Methods and compositions for improving detection and/or capture of a target entity
JP6649250B2 (ja) 2013-05-21 2020-02-19 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ 操作されたヘム結合性構成物およびその使用
US10513546B2 (en) 2013-12-18 2019-12-24 President And Fellows Of Harvard College CRP capture/detection of gram positive bacteria
EP3088451B1 (en) * 2015-04-30 2018-02-21 VITO NV (Vlaamse Instelling voor Technologisch Onderzoek NV) Plasma assisted hydrophilicity enhancement of polymer materials

Also Published As

Publication number Publication date
IL291447A (en) 2022-05-01
JP2022141661A (ja) 2022-09-29
US20190144567A1 (en) 2019-05-16
JP7163192B2 (ja) 2022-10-31
CA3024490A1 (en) 2017-11-23
US11919971B2 (en) 2024-03-05
JP2019522630A (ja) 2019-08-15
KR20190020668A (ko) 2019-03-04
IL263017A (en) 2018-12-31
IL263017B (en) 2022-04-01
EP3458483A1 (en) 2019-03-27
CN109476764A (zh) 2019-03-15
WO2017201064A1 (en) 2017-11-23

Similar Documents

Publication Publication Date Title
US11919971B2 (en) Aqueous biomolecule coupling on CO2-plasma-activated surfaces
EP2875078B1 (en) Modification of surfaces for simulataneous repellency and targeted binding of desired moieties
US10865235B2 (en) Engineered microbe-targeting molecules and uses thereof
US11807677B2 (en) Microbe-binding molecules and uses thereof
US20220195017A1 (en) Pathogen binding methods and compositions
AU2013225823A1 (en) Rapid antibiotic susceptibility testing
HK1230278B (en) Engineered microbe-targeting molecules and uses thereof
HK1230278A1 (en) Engineered microbe-targeting molecules and uses thereof

Legal Events

Date Code Title Description
MK5 Application lapsed section 142(2)(e) - patent request and compl. specification not accepted