AU2016258837B2 - Peptide compositions and methods of use - Google Patents

Peptide compositions and methods of use Download PDF

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Publication number
AU2016258837B2
AU2016258837B2 AU2016258837A AU2016258837A AU2016258837B2 AU 2016258837 B2 AU2016258837 B2 AU 2016258837B2 AU 2016258837 A AU2016258837 A AU 2016258837A AU 2016258837 A AU2016258837 A AU 2016258837A AU 2016258837 B2 AU2016258837 B2 AU 2016258837B2
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AU
Australia
Prior art keywords
compound
composition
retinal
administered
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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AU2016258837A
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English (en)
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AU2016258837A1 (en
Inventor
Cagri G. Besirli
Alexander J. Bridges
John K. Freshley
William A. Hunke
Linda L. Johnson
Francis X. Smith
Ethan SYLVAIN
David N. Zacks
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Michigan System
ONL Therapeutics Inc
Original Assignee
University of Michigan System
ONL Therapeutics Inc
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Publication date
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Publication of AU2016258837A1 publication Critical patent/AU2016258837A1/en
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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Agronomy & Crop Science (AREA)
  • Environmental Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
AU2016258837A 2015-05-01 2016-04-29 Peptide compositions and methods of use Active AU2016258837B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562155711P 2015-05-01 2015-05-01
US62/155,711 2015-05-01
PCT/US2016/030098 WO2016178993A1 (en) 2015-05-01 2016-04-29 Peptide compositions and methods of use

Publications (2)

Publication Number Publication Date
AU2016258837A1 AU2016258837A1 (en) 2017-11-09
AU2016258837B2 true AU2016258837B2 (en) 2020-12-03

Family

ID=57217771

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2016258837A Active AU2016258837B2 (en) 2015-05-01 2016-04-29 Peptide compositions and methods of use

Country Status (21)

Country Link
US (5) US10508134B2 (enExample)
EP (3) EP3288379B1 (enExample)
JP (2) JP6884755B2 (enExample)
KR (2) KR20240046280A (enExample)
CN (2) CN113651873B (enExample)
AU (1) AU2016258837B2 (enExample)
CA (1) CA2984154A1 (enExample)
CY (1) CY1124911T1 (enExample)
DK (1) DK3288379T3 (enExample)
EA (2) EA035293B1 (enExample)
ES (1) ES2906173T3 (enExample)
HR (1) HRP20220138T1 (enExample)
HU (1) HUE057883T2 (enExample)
LT (1) LT3288379T (enExample)
MX (1) MX387317B (enExample)
PL (1) PL3288379T3 (enExample)
PT (1) PT3288379T (enExample)
RS (1) RS62866B1 (enExample)
SI (1) SI3288379T1 (enExample)
SM (1) SMT202200069T1 (enExample)
WO (1) WO2016178993A1 (enExample)

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CN113651873B (zh) * 2015-05-01 2025-09-02 Onl医疗股份有限公司 肽组合物和使用方法
WO2019183246A1 (en) * 2018-03-20 2019-09-26 Onl Therapeutics, Inc. Compositions and methods of fas inhibition
US20210121534A1 (en) * 2018-06-19 2021-04-29 Cella Therapeutics, Llc Sustained-release drug delivery systems comprising an intraocular pressure lowering agent, a cnp compound, an npr-b compound, a tie-2 agonist, or neurotrophic agent for use for treating glaucoma or ocular hypertension
KR20220118499A (ko) * 2019-12-18 2022-08-25 셀라 테라퓨틱스, 엘엘씨 신경영양제, 세포자멸 신호전달 단편 억제제(FAS) 또는 FAS 리간드(FASL) 억제제, 종양 괴사 인자-α(TNF-α) 또는 TNF 수용체 억제제, 미토콘드리아 펩티드, 올리고뉴클레오티드, 케모카인 억제제 또는 시스테인-아스파틱 프로테아제 억제제를 포함하는 약물 전달 시스템
EP4355349A4 (en) * 2021-06-15 2025-04-16 ONL Therapeutics, Inc. Methods and compositions for treating eye diseases and disorders
JP2024525805A (ja) * 2021-07-13 2024-07-12 オーエヌエル セラピューティクス，インク． 眼の疾患および障害における視機能を改善するための方法および組成物
US20250163131A1 (en) * 2021-12-27 2025-05-22 Onl Therapeutics, Inc. Sfasl for inhibiting rpe cell death and associated disorders
EP4565595A2 (en) * 2022-08-05 2025-06-11 ONL Therapeutics, Inc. Peptide compositions and methods of use
EP4565596A1 (en) * 2022-08-05 2025-06-11 ONL Therapeutics, Inc. Peptide compositions and methods of use
WO2024220669A1 (en) * 2023-04-19 2024-10-24 Onl Therapeutics, Inc. Methods and compositions for treating rnfl thinning

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US20100226878A1 (en) * 2009-03-03 2010-09-09 The Regents Of The University Of Michigan Methods of inhibiting photoreceptor apoptosis
US20140371161A1 (en) * 2012-01-18 2014-12-18 Governing Council Of The University Of Toronto Novel peptides and methods and uses thereof for preventing retinal disorders

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Also Published As

Publication number Publication date
HUE057883T2 (hu) 2022-06-28
WO2016178993A1 (en) 2016-11-10
AU2016258837A1 (en) 2017-11-09
PT3288379T (pt) 2022-02-08
KR102652804B1 (ko) 2024-04-01
US20180291062A1 (en) 2018-10-11
CA2984154A1 (en) 2016-11-10
CN107708416A (zh) 2018-02-16
CY1124911T1 (el) 2023-01-05
JP2021120400A (ja) 2021-08-19
HRP20220138T1 (hr) 2022-05-27
EP3997981A1 (en) 2022-05-18
BR112017023479A2 (pt) 2018-07-24
CN113651873B (zh) 2025-09-02
US11597749B2 (en) 2023-03-07
US20250346631A1 (en) 2025-11-13
EP3288379A4 (en) 2018-10-24
US20230287052A1 (en) 2023-09-14
US10508134B2 (en) 2019-12-17
EA202090184A2 (ru) 2020-05-31
ES2906173T3 (es) 2022-04-13
US20210094985A1 (en) 2021-04-01
EA202090184A3 (ru) 2020-07-31
LT3288379T (lt) 2022-02-25
SMT202200069T1 (it) 2022-03-21
EA035293B1 (ru) 2020-05-26
MX387317B (es) 2025-03-18
MX2017014075A (es) 2018-07-06
EP3288379A1 (en) 2018-03-07
RS62866B1 (sr) 2022-02-28
EP4623925A2 (en) 2025-10-01
KR20170140383A (ko) 2017-12-20
JP6884755B2 (ja) 2021-06-09
US20200123201A1 (en) 2020-04-23
PL3288379T3 (pl) 2022-03-07
SI3288379T1 (sl) 2022-06-30
KR20240046280A (ko) 2024-04-08
CN113651873A (zh) 2021-11-16
DK3288379T3 (da) 2022-02-07
US12258425B2 (en) 2025-03-25
HK1251979A1 (zh) 2019-05-10
EA201792399A1 (ru) 2018-05-31
CN107708416B (zh) 2021-06-29
JP2018514590A (ja) 2018-06-07
US10829518B2 (en) 2020-11-10
EP3288379B1 (en) 2021-11-03

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