AU2016255573A1 - Multiplexed optimized mismatch amplification (MOMA)-real time PCR for assessing cell-free DNA - Google Patents
Multiplexed optimized mismatch amplification (MOMA)-real time PCR for assessing cell-free DNA Download PDFInfo
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- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
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- C12Q1/6844—Nucleic acid amplification reactions
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- C12Q1/6858—Allele-specific amplification
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| US11111543B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US9424392B2 (en) | 2005-11-26 | 2016-08-23 | Natera, Inc. | System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals |
| US11111544B2 (en) | 2005-07-29 | 2021-09-07 | Natera, Inc. | System and method for cleaning noisy genetic data and determining chromosome copy number |
| US12152275B2 (en) | 2010-05-18 | 2024-11-26 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11332793B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11408031B2 (en) | 2010-05-18 | 2022-08-09 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| US11332785B2 (en) | 2010-05-18 | 2022-05-17 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US11339429B2 (en) | 2010-05-18 | 2022-05-24 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| EP2572003A4 (en) | 2010-05-18 | 2016-01-13 | Natera Inc | METHOD FOR NONINVASIVE PRANATAL PLOIDIE ASSIGNMENT |
| US20190010543A1 (en) | 2010-05-18 | 2019-01-10 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10316362B2 (en) | 2010-05-18 | 2019-06-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11326208B2 (en) | 2010-05-18 | 2022-05-10 | Natera, Inc. | Methods for nested PCR amplification of cell-free DNA |
| US9677118B2 (en) | 2014-04-21 | 2017-06-13 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US11322224B2 (en) | 2010-05-18 | 2022-05-03 | Natera, Inc. | Methods for non-invasive prenatal ploidy calling |
| US12221653B2 (en) | 2010-05-18 | 2025-02-11 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| WO2012088456A2 (en) | 2010-12-22 | 2012-06-28 | Natera, Inc. | Methods for non-invasive prenatal paternity testing |
| AU2011358564B9 (en) | 2011-02-09 | 2017-07-13 | Natera, Inc | Methods for non-invasive prenatal ploidy calling |
| AU2013249012B2 (en) | 2012-04-19 | 2019-03-28 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| US20140100126A1 (en) | 2012-08-17 | 2014-04-10 | Natera, Inc. | Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data |
| EP3957749A1 (en) | 2014-04-21 | 2022-02-23 | Natera, Inc. | Detecting tumour specific mutations in biopsies with whole exome sequencing and in cell-free samples |
| US20180173845A1 (en) | 2014-06-05 | 2018-06-21 | Natera, Inc. | Systems and Methods for Detection of Aneuploidy |
| US20180142296A1 (en) * | 2015-04-30 | 2018-05-24 | Medical College Of Wisconsin, Inc. | Multiplexed optimized mismatch amplification (moma)-real time pcr for assessing cell-free dna |
| WO2016183106A1 (en) | 2015-05-11 | 2016-11-17 | Natera, Inc. | Methods and compositions for determining ploidy |
| WO2017181202A2 (en) | 2016-04-15 | 2017-10-19 | Natera, Inc. | Methods for lung cancer detection |
| BR112018072196A2 (pt) * | 2016-04-29 | 2019-02-12 | Medical College Wisconsin Inc | amplificação de incompatibilidade otimizada multiplexadas (moma) - número do alvo |
| EP3449018A4 (en) * | 2016-04-29 | 2019-11-06 | The Medical College of Wisconsin, Inc. | REAL-TIME PCR WITH MULTIPLEXED OPTIMIZED MISMATCH AMPLIFICATION (MOMA) FOR THE EVALUATION OF FETAL WELL-BEING |
| JP2019518437A (ja) * | 2016-04-29 | 2019-07-04 | ザ メディカル カレッジ オブ ウィスコンシン インクＴｈｅ Ｍｅｄｉｃａｌ Ｃｏｌｌｅｇｅ Ｏｆ Ｗｉｓｃｏｎｓｉｎ， Ｉｎｃ． | 多重／最適化ミスマッチ増幅（ｍｏｍａ）−がんの評価のためのリアルタイムｐｃｒ |
| US11485996B2 (en) | 2016-10-04 | 2022-11-01 | Natera, Inc. | Methods for characterizing copy number variation using proximity-litigation sequencing |
| CN110114477A (zh) * | 2016-11-02 | 2019-08-09 | 威斯康星州立大学医学院 | 用于使用总的和特异性无细胞dna评估风险的方法 |
| CA3042722A1 (en) * | 2016-11-02 | 2018-05-11 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using mismatch amplification and statistical methods |
| GB201618485D0 (en) | 2016-11-02 | 2016-12-14 | Ucl Business Plc | Method of detecting tumour recurrence |
| US10011870B2 (en) | 2016-12-07 | 2018-07-03 | Natera, Inc. | Compositions and methods for identifying nucleic acid molecules |
| AU2018288835A1 (en) | 2017-06-20 | 2020-01-16 | The Medical College Of Wisconsin, Inc. | Assessing conditions in transplant subjects using donor-specific cell-free DNA |
| CA3067635A1 (en) * | 2017-06-20 | 2018-12-27 | The Medical College Of Wisconsin, Inc. | Transplant patient monitoring with cell-free dna |
| AU2018288832B2 (en) | 2017-06-20 | 2025-03-06 | The Medical College Of Wisconsin, Inc. | Assessing transplant complication risk with total cell-free DNA |
| JP2020531050A (ja) * | 2017-08-17 | 2020-11-05 | ティーエーアイ ダイアグノスティックス インコーポレイテッドＴａｉ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | ドナー遺伝子型なしでドナー無細胞ｄｎａを決定する方法 |
| JP2021506342A (ja) | 2017-12-14 | 2021-02-22 | ティーエーアイ ダイアグノスティックス インコーポレイテッドＴａｉ Ｄｉａｇｎｏｓｔｉｃｓ，Ｉｎｃ． | 移植のための移植片適合性の評価 |
| SG11202005474RA (en) * | 2017-12-15 | 2020-07-29 | Acrannolife Genomics Pvt Ltd | A non-invasive method for monitoring transplanted organ status in organ-transplant recipients |
| CA3090426A1 (en) | 2018-04-14 | 2019-10-17 | Natera, Inc. | Methods for cancer detection and monitoring by means of personalized detection of circulating tumor dna |
| US12234509B2 (en) | 2018-07-03 | 2025-02-25 | Natera, Inc. | Methods for detection of donor-derived cell-free DNA |
| EP3899033A4 (en) * | 2018-12-17 | 2022-10-19 | The Medical College of Wisconsin, Inc. | Assessing risk with total cell-free dna |
| WO2020206290A1 (en) * | 2019-04-03 | 2020-10-08 | The Medical College Of Wisconsin, Inc. | Methods for assessing risk using total cell-free dna |
| US11931674B2 (en) | 2019-04-04 | 2024-03-19 | Natera, Inc. | Materials and methods for processing blood samples |
| EP3980559A1 (en) | 2019-06-06 | 2022-04-13 | Natera, Inc. | Methods for detecting immune cell dna and monitoring immune system |
| WO2021236962A1 (en) | 2020-05-20 | 2021-11-25 | The Medical College Of Wisconsin, Inc. | Compositions and methods for inhibiting cytokine-release syndrome |
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| EP1325963B1 (en) * | 2001-12-24 | 2006-09-27 | Wolfgang Prof. Holzgreve | Method for non-invasive diagnosis of transplantations and transfusions |
| HUE052213T2 (hu) * | 2009-11-06 | 2021-04-28 | Univ Leland Stanford Junior | Grafitkilökõdés nem invazív diagnosztizálása szervátültetett betegekben |
| US20130143219A1 (en) * | 2010-01-28 | 2013-06-06 | Medical College of Wisconsin Inc. | Methods and compositions for high yield, specific amplification |
| CN102892901B (zh) * | 2010-03-24 | 2015-11-25 | 凸版印刷株式会社 | 利用竞争性引物的目标碱基序列的检测方法 |
| AU2013249012B2 (en) * | 2012-04-19 | 2019-03-28 | The Medical College Of Wisconsin, Inc. | Highly sensitive surveillance using detection of cell free DNA |
| CN105339507A (zh) * | 2013-02-21 | 2016-02-17 | 托马生物科学公司 | 用于核酸分析的方法、组合物和试剂盒 |
| DK3004388T4 (da) * | 2013-05-29 | 2023-08-28 | Chronix Biomedical | Påvisning og kvantificering af cellefrit dna fra donor i kredsløbet hos organtransplantatmodtagere |
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2017
- 2017-10-29 IL IL255301A patent/IL255301B/en unknown
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2021
- 2021-08-03 JP JP2021127555A patent/JP2022002508A/ja active Pending
- 2021-12-26 IL IL289404A patent/IL289404A/en unknown
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2022
- 2022-05-23 AU AU2022203482A patent/AU2022203482A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP3289102A1 (en) | 2018-03-07 |
| IL255301B (en) | 2022-02-01 |
| CN107849604A (zh) | 2018-03-27 |
| IL255301A0 (en) | 2017-12-31 |
| IL289404A (en) | 2022-02-01 |
| BR112017023232A2 (pt) | 2018-08-07 |
| HK1252152A1 (zh) | 2019-05-17 |
| WO2016176662A1 (en) | 2016-11-03 |
| JP2022002508A (ja) | 2022-01-11 |
| AU2022203482A1 (en) | 2022-06-09 |
| JP2018514219A (ja) | 2018-06-07 |
| MX2017013878A (es) | 2018-06-22 |
| US20180142296A1 (en) | 2018-05-24 |
| CA2984352A1 (en) | 2016-11-03 |
| EA201792389A1 (ru) | 2018-05-31 |
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