AU2015349870B2 - Enzyme- and amplification-free sequencing - Google Patents
Enzyme- and amplification-free sequencing Download PDFInfo
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- AU2015349870B2 AU2015349870B2 AU2015349870A AU2015349870A AU2015349870B2 AU 2015349870 B2 AU2015349870 B2 AU 2015349870B2 AU 2015349870 A AU2015349870 A AU 2015349870A AU 2015349870 A AU2015349870 A AU 2015349870A AU 2015349870 B2 AU2015349870 B2 AU 2015349870B2
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- Prior art keywords
- nucleic acid
- detectable label
- acid molecule
- sequencing
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
- C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6869—Methods for sequencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/113—Modifications characterised by incorporating modified backbone
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2537/00—Reactions characterised by the reaction format or use of a specific feature
- C12Q2537/10—Reactions characterised by the reaction format or use of a specific feature the purpose or use of
- C12Q2537/149—Sequential reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2563/00—Nucleic acid detection characterized by the use of physical, structural and functional properties
- C12Q2563/179—Nucleic acid detection characterized by the use of physical, structural and functional properties the label being a nucleic acid
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2019275665A AU2019275665B2 (en) | 2014-11-21 | 2019-12-06 | Enzyme- and amplification-free sequencing |
| AU2022271472A AU2022271472B2 (en) | 2014-11-21 | 2022-11-18 | Enzyme- and amplification-free sequencing |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201462082883P | 2014-11-21 | 2014-11-21 | |
| US62/082,883 | 2014-11-21 | ||
| PCT/US2015/061615 WO2016081740A1 (en) | 2014-11-21 | 2015-11-19 | Enzyme- and amplification-free sequencing |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019275665A Division AU2019275665B2 (en) | 2014-11-21 | 2019-12-06 | Enzyme- and amplification-free sequencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| AU2015349870A1 AU2015349870A1 (en) | 2017-06-08 |
| AU2015349870B2 true AU2015349870B2 (en) | 2019-09-26 |
Family
ID=54705918
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2015349870A Active AU2015349870B2 (en) | 2014-11-21 | 2015-11-19 | Enzyme- and amplification-free sequencing |
| AU2019275665A Active AU2019275665B2 (en) | 2014-11-21 | 2019-12-06 | Enzyme- and amplification-free sequencing |
| AU2022271472A Active AU2022271472B2 (en) | 2014-11-21 | 2022-11-18 | Enzyme- and amplification-free sequencing |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2019275665A Active AU2019275665B2 (en) | 2014-11-21 | 2019-12-06 | Enzyme- and amplification-free sequencing |
| AU2022271472A Active AU2022271472B2 (en) | 2014-11-21 | 2022-11-18 | Enzyme- and amplification-free sequencing |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20160194701A1 (enExample) |
| EP (4) | EP4029952B1 (enExample) |
| JP (4) | JP6674951B2 (enExample) |
| KR (4) | KR102738175B1 (enExample) |
| CN (2) | CN113403373B (enExample) |
| AU (3) | AU2015349870B2 (enExample) |
| CA (1) | CA2968376C (enExample) |
| ES (2) | ES2770055T3 (enExample) |
| SG (1) | SG11201704098VA (enExample) |
| WO (1) | WO2016081740A1 (enExample) |
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| CA2850509C (en) | 2011-10-14 | 2023-08-01 | President And Fellows Of Harvard College | Sequencing by structure assembly |
| ES2952728T3 (es) | 2011-12-22 | 2023-11-03 | Harvard College | Métodos para la detección de analitos |
| WO2014163886A1 (en) | 2013-03-12 | 2014-10-09 | President And Fellows Of Harvard College | Method of generating a three-dimensional nucleic acid containing matrix |
| ES2991004T3 (es) | 2011-12-22 | 2024-12-02 | Harvard College | Métodos para la detección de analitos |
| US9914967B2 (en) | 2012-06-05 | 2018-03-13 | President And Fellows Of Harvard College | Spatial sequencing of nucleic acids using DNA origami probes |
| KR102884236B1 (ko) | 2013-06-04 | 2025-11-12 | 프레지던트 앤드 펠로우즈 오브 하바드 칼리지 | Rna-가이드된 전사 조절 |
| CN111500680B (zh) | 2013-06-25 | 2024-04-16 | 普罗格诺西斯生物科学公司 | 检测样品中生物靶标的空间分布的方法和系统 |
| WO2016007839A1 (en) | 2014-07-11 | 2016-01-14 | President And Fellows Of Harvard College | Methods for high-throughput labelling and detection of biological features in situ using microscopy |
| US10240146B2 (en) | 2014-07-30 | 2019-03-26 | President And Fellows Of Harvard College | Probe library construction |
| EP4321627A3 (en) | 2015-04-10 | 2024-04-17 | 10x Genomics Sweden AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| US10640816B2 (en) | 2015-07-17 | 2020-05-05 | Nanostring Technologies, Inc. | Simultaneous quantification of gene expression in a user-defined region of a cross-sectioned tissue |
| US10501777B2 (en) | 2015-07-17 | 2019-12-10 | Nanostring Technologies, Inc. | Simultaneous quantification of a plurality of proteins in a user-defined region of a cross-sectioned tissue |
| GB2559526B (en) | 2015-11-03 | 2021-02-17 | Harvard College | Method and apparatus for volumetric imaging of a three-dimensional nucleic acid containing matrix |
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